Clinical Trials
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Are you ages 40-80 and scheduled for a knee or hip replacement due to arthritis?

You may be eligible for the TWEAK Trial. A randomized clinical trial at UAB to determine if strength training rehabilitation improves recovery after joint replacement. Participants receive free health and functional status monitoring, free body composition and fitness testing, $500 for participation, and free personal exercise testing (half of the participants). Supervised exercise training program with certified trainers (half of participants): 3 days per week for 16 weeks at the Exercise Clinical Trials Facility at UAB. For more information, please call 205-934-6231.

Healthy volunteers needed for exercise, blood pressure study

Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians with no history of diabetes, heart problems or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.

Participants diagnosed with relapsing-remitting multiple sclerosis needed for research study focused on improving dietary habits

This study will utilize an online telehealth program to deliver diet and exercise recommendations. To participate in this study you must be ages 21-65, have a diagnosis of relapsing-remitting MS, have internet access and want to improve your diet. Participation is free, and compensation is provided. For more information, please call Alex Yates at 205-403-5525 or hbdlab@uabmc.edu

Simulated-altitude to optimize aerobic exercise among breast cancer survivors with limited mobility study

Are you a breast cancer survivor having difficulty walking? Do you have any lower-body pain that is restricting your mobility? If so, you may be interested in taking part in an exercise training intervention. UAB researchers are looking for overweight women  - age 18-70 with a body mass index between 30-45 kg/m2 - with a history of breast cancer to participate in a novel exercise training study. Volunteers will be asked to attend two assessment sessions: an initial assessment and after 8 weeks of exercise to collect information about your health status. Further eligibility screening will be conducted by telephone. Volunteers must reside in or near Jefferson County. The study will evaluate a novel exercise training strategy designed to mimic exercise at higher altitude to support improved health and mobility among breast cancer survivors. Contact Dr. Stephen J. Carter, 205-975-0269 or carters@uab.edu; or the UAB Exercise and Cancer Research Team, 205.934.5466 or moveforward@uab.edu; to learn more.

Volunteers diagnosed with a history of stroke needed for exercise study

This study will examine the effectiveness of a group exercise class on the health and function adults age 18-65 with a history of stroke. You will be randomly assigned to one of two groups; Movement2Music or a waitlist group who will complete a home-based exercise intervention. Email caseyh@lakeshore.org or call 205-313-7455 for more information. Participation is free, and compensation is provided.

Volunteers needed for exercise and blood pressure study

Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians and have no history of diabetes, heart problems, or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.

Want to get in better shape? Learn about the PHITE study

Are you ages 18–27, in good health and wish you had a personal trainer? You may qualify for the PHITE study. PHITE is a randomized exercise dose response trial to better understand how exercise induces health benefits. Visit www.uab.edu/PHITE-trial; participants receive supervised exercise training with certified trainers, valuable information about their health, and up to $1000 compensation for their time. Funded by the US Department of Defense.

research match

By taking part in a clinical trial at UAB, you can help generate knowledge that will change the world. Volunteers play a vital role in UAB's internationally renowned research enterprise.

You can also join ResearchMatch, a multi-institution project that pairs volunteers with researchers seeking study participants.

Trials currently available at UAB are listed above; click the tags to refine the list or search for a specific trial. To submit a trial for inclusion in this list, click here.