HVTN 124 is a Phase 1 clinical trial to test the safety and immune response of 1 experimental vaccine and adjuvant (a substance to “alert” the immune system) in healthy, HIV-uninfected adults ages 18-50. The study is 14 months in length with 13 visits to our clinic for the duration of the study. Of those 13 visits, you will be vaccinated at 5 visits. Visits to our clinic range from 30-90 minutes and entail a brief physical exam, small blood draw, vaccinations, HIV counseling and testing, and completion of a diary. You are compensated for your time and travel at $75 for initial screening and for follow-up visits, and $100 for the vaccination visits.
The study will test the safety and acceptability of a new rectal gel, which is being developed to protect against HIV infection during anal sex. If you are HIV negative and have had receptive anal sex at least once in your life, you may be eligible to participate. The study involves 9 visits over a period of about 3-5 months. During this time, you will insert the gel, rectally, a total of 3 times. Rectal biopsies will be collected at 5 of the visits. Physical exams and HIV/STI testing will be provided at no cost, and you will be compensated up to $1,375 for your time. For more information, call (205) 996-4405.