Yuhua Song, Ph.D.

Research Description

My research group is currently using integrated multi-scale computational modeling and biochemical and biological experimental approaches to investigate the fundamental structural and functional mechanisms of the biomolecular interactions underlying the apoptosis and cell adhesion signaling pathways, and to identify and develop cancer chemotherapic agents to regulate the apoptosis signaling pathway. We also investigate the molecular mechanisms of the cytotoxicity resulting from the alterations of biomembrane mechanics and electrostatics by biomaterials and small molecules. This will facilitate the design of optimal biomaterials and small molecules with minimal toxicity for cell-based therapeutics. Methodology development for multiscale modeling to study complex biological systems also continues to be a focus of my research group.

Email:  yhsong@uab.edu