Lab Resources
Our lab is situated in the Wallace Tumor Institute within the Division of Developmental and Clinical Immunology of the University of Alabama at Birmingham. The lab is well equipped for all kinds of tissue culture and hybridoma production. It also has the capabilities for protein expression (E. coli, Drosophila, Sf9 and mammalian cell culture, and protein purification (Pharmacia, AKTA FPLC).
The lab has state of the art flow cytometry equipment including a high-speed Mo-Flo cell sorter (Cytomation), FACS IV star cell sorter, and FACScan and FACScalibur flow cytometers (the latter is available for hands on use).
The imaging facility contains a Leica DMRB vertical research microscope equipped with a C5180 Hamamatsu Digital Camera and imaging software. We also have an automated Leica DMR IRBE inverted microscope equipped with fluorescence and phase contrast. Improvision Openlab control and analysis software for this microscope facilitates real time 4 color, deconvolution, confocal microscopy of live-cell culture and cellular interactions using Bioptics micro-environmentally controlled chambers.
There is a well-equipped histology laboratory with cryostat and paraffin embedding equipment.
We have a state of the art animal facility maintained by UAB Animal Resources for the production and support of normal and immunocompromised nude and scid mice and housing of transgenic mice.
There
are a large number of specialized
core facilities available on campus. These include a fully equipped
electron
microscope facility, nucleotide
sequencing core facility, media
preparation facility, and fermentation
facility. There is a transgenic
mouse facility to which we have ample access. Of particular
importance
is a new High
Resolution Imaging Core Facility which has three Leica TCS
NT confocal instruments equipped with an assortment of lasers and
equipped
for two photon microscopy.
Graduate
Education
The Department of
Microbiology along
with the Cell and
Molecular Biology Program at UAB offer a large number
of opportunities for graduate education. Please contact Debbie
Sirles via email (sirles@uab.edu) for more information.
Postdoctoral
Positions
Postdoctoral
positions are available
for all of the projects
described on this site.
UAB has recently instituted the Frederick Gardner Cottrell Postdoctoral
Enhancement Awards.
The purpose of these awards is to recruit postdoctoral fellows with
outstanding credentials and exceptional promise to UAB. Each awardee
will receive an annual stipend of at least $50,000 for two years and
$3,500 annually for travel and professional development. More
information
can be obtained by visiting the website http://www.postdocs.uab.edu/cottrell.htm.
Candidates should have experience in cell and/or molecular immunology.
More specific inquiries about the projects or applying for positions
can be done by email. Please send a CV and the names of three
references
to Dr. John
Kearney at John.Kearney@ccc.uab.edu.