Publications

2013

  1. Mestecky J, Raska M, Julian BA, Gharavi AG, Renfrow MB, Moldoveanu Z, Novak L, Matousovic K, Novak J.
    IgA nephropathy: molecular mechanisms of the disease.
    Annu Rev Pathol. 2013 Jan 24;8:217-40.

  2. Novak J, Renfrow MB, Gharavi AG, Julian BA.
    Pathogenesis of immunoglobulin A nephropathy.
    Curr Opin Nephrol Hypertens. 2013 Mar 18. [Epub ahead of print]

  3. Zhang Z, Jones A, Joo HY, Zhou D, Cao Y, Chen S, Erdjument-Bromage H, Renfrow M, He H, Tempst P, Townes TM, Giles KE, Ma L, Wang H.
    USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.
    Genes Dev. 2013 Jul 15;27(14):1581-95.

  4. Franc V, Rehulka P, Raus M, Stulík J, Novak J, Renfrow MB, Sebela M.
    Elucidating heterogeneity of IgA1 hinge-region O-glycosylation by use of MALDI-TOF/TOF mass spectrometry: Role of cysteine alkylation during sample processing.
    J Proteomics. 2013 Jul 24. [Epub ahead of print]

  5. Xu Y, Yang H, Joo HY, Yu JH, Smith AD 4th, Schneider D, Chow LT, Renfrow M, Wang H.
    Ubp-M serine 552 phosphorylation by cyclin-dependent kinase 1 regulates cell cycle progression.
    Cell Cycle. 2013 Sep 4;12(19). [Epub ahead of print]

  6. Jordan DS, Daubenspeck JM, Laube AH, Renfrow MB, Dybvig K.
    O-linked protein glycosylation in mycoplasma
    Mol. Microbiol. 2013 Oct 4. [Epub ahead of print]

  7. Hastings MC, Moldoveanu Z, Suzuki H, Berthoux F, Julian BA, Sanders JT, Renfrow MB, Novak J, Wyatt RJ.
    Biomarkers in IgA nephropathy: relationship to pathogenetic hits.
    Expert Opin Med Diagn. 2013 Nov;7(6):615-27.

  8. Boerma LJ, Xia G, Qui C, Cox BD, Chalmers MJ, Smith CD, Lobo-Ruppert S, Griffin P, Muccio DD, Renfrow MB.
    Defining the communication between agonist and coactivator binding in the retinoid X receptor ligand binding domain.
    J Biol Chem. 2013 Nov 1. [Epub ahead of print]

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2012

  1. Horynová M, Takahashi K, Hall S, Renfrow MB, Novak J, Raška M.
    Production of N-acetylgalactosaminyl-transferase 2 (GalNAc-T2) fused with secretory signal Igκ in insect cells.
    Protein Expr Purif. 2012 Feb;81(2):175-80.

  2. Takahashi K, Smith AD, Poulsen K, Kilian M, Julian BA, Mestecky J, Novak J, Renfrow MB.
    Naturally occurring structural isomers in serum IgA1 o-glycosylation.
    J Proteome Res. 2012 Feb 3;11(2):692-702.

  3. Lai YS, Chang CW, Pawlik KM, Zhou D, Renfrow MB, Townes TM.
    SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.
    Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3772-7.

  4. Novak J, Julian BA, Mestecky J, Renfrow MB.
    Glycosylation of IgA1 and pathogenesis of IgA nephropathy.
    Semin Immunopathol. 2012 May;34(3):365-82.

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2011

  1. Joo HY, Jones A, Yang C, Zhai L, Smith AD 4th, Zhang Z, Chandrasekharan MB, Sun ZW, Renfrow MB, Wang Y, Chang C, Wang H.
    Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.
    J Biol Chem. 2011 Mar 4;286(9):7190-201.

  2. Webber PJ, Smith AD, Sen S, Renfrow MB, Mobley JA, West AB.
    Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.
    J Mol Biol. 2011 Sep 9;412(1):94-110.

  3. Suzuki H, Kiryluk K, Novak J, Moldoveanu Z, Herr AB, Renfrow MB, Wyatt RJ, Scolari F, Mestecky J, Gharavi AG, Julian BA.
    The pathophysiology of IgA nephropathy.
    J Am Soc Nephrol. 2011 Oct;22(10):1795-803.

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2010

  1. Xia G, Boerma LJ, Cox BD, Qiu C, Kang S, Smith CD, Renfrow MB, Muccio DD.
    Structure, Energetics, and Dynamics of Binding Coactivator Peptide to the Human Retinoid X Receptor α Ligand Binding Domain Complex with 9-cis-Retinoic Acid.
    Biochemistry. 2010 Dec 8. [Epub ahead of print]

  2. Takahashi, K., Wall, S.B., Suzuki, H., Hall, S. Smith, A.D.,IV, Poulsen, K., Kilian, M., Julian, B.A., Mestecky, J., Novak, J., Renfrow, M.B.,
    "Clustered O-glycans of IgA1: Defining macro- and micro- heterogeneity by use of electron capture/transfer dissociation"
    Mol. Cell. Proteomics Epub Sep 7. 2010

  3. Raska, M., Takahashi, K., Hall, S., Moldoveanu, Z., Elliot, Wilson, L., Brown, R., Barnes, S., Tomana, M., Smith, Mestecky, J., Renfrow, M.B., Novak, J.
    Glycosylation pattern of HIV-1 gp120 is cell specific and affects binding of neutralizing antibodies.
    J. Biol. Chem. Epub May 3, 2010

  4. Stella, D.R., Floyd, K.A., Grey, A.C., Renfrow, M.B., Schey, K.L., and Barnes S.
    Tissue localization and biophysical properties of α-crystallin and its numerous truncation products in the cataractous ICR/f rat lens.
    Invest. Ophthalmol Vis Sci. Epub Apr 30, 2010

  5. Zhang, Y., Smith, A.D., IV, Renfrow M.B., Schneider, D.A.
    The Paf1 complex directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.
    J. Biol. Chem. Epub ahead of print Mar 18, 2010

  6. Wada, Y., Dell, A., Haslam, S.M., Tissot, B., Canis, K., Azadi, P., Backstrom, M., Costello, C.E., Hansson, G.C., Hiki, Y., ishihara, M., Ito, H., Kakehi, K., Karlsson, N., Koichi, K., Kawasaki, N., Khoo, K.-H., Kobayashi, K., Kolarich, D., Kondo, A., Lebrilla, C., Nakano, M., narimatsu, H., Novak, J., Novotny, M.V., Packer, N.H., Renfrow, M.B., Tajiri, M., Thomsson, K.A., Yu, S.-Y., Taniguchi, N.
    Comparison of methods for profiling O-glycosylation: HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study of IgA1.
    Mol Cell. Proteomics. Apr 9(4):719-27, 2010

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2009

  1. Huijbregts RP, Svitin A, Stinnett MW, Renfrow MB, Chesnokov I.
    Drosophila Orc6 Facilitates GTPase Activity and Filament Formation of the Septin Complex.
    Molecular Biology of the Cell. 20(1):270-81, 2009

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2008

  1. Gomes MM, Wall SB, Takahashi K, Novak J, Renfrow MB, Herr AB.
    Analysis of IgA1 N-glycosylation and its contribution to FcalphaRI binding.
    Biochemistry. 28;47(43):11285-99, 2008

  2. Barnes S, Shonsey EM, Eliuk SM, Stella D, Barrett K, Srivastava OP, Kim H, Renfrow MB.
    High-resolution mass spectrometry analysis of protein oxidations and resultant loss of function.
    Biochemical Society Transactions. 36:1037-44, 2008

  3. Kang S, Poliakov A, Sexton J, Renfrow MB, Prevelige PE Jr.
    Probing conserved helical modules of portal complexes by mass spectrometry-based hydrogen/deuterium exchange.
    Journal of Molecular Biology. 381(3):772-84, 2008

  4. Isbell TS, Sun CW, Wu LC, Teng X, Vitturi DA, Branch BG, Kevil CG, Peng N, Wyss JM, Ambalavanan N, Schwiebert L, Ren J, Pawlik KM, Renfrow MB, Patel RP, Townes TM.
    SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.
    Nature Medicine, 14(7):773-7, 2008

  5. Mestecky J, Tomana M, Moldoveanu Z, Julian BA, Suzuki H, Matousovic K, Renfrow MB, Novak L, Wyatt RJ, Novak J.
    Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy. Kidney Blood Press Res. 31:29-37, 2008

  6. Peng, L., Wang, D., Lucas, J., Oparil, S., Xing, D., Cau, X., Novak, L., Renfrow, M.B., Chen, Y.-F.
    Atrial Natriuretic Peptide Inhibits Transforming Growth Factor β-Induced Smad Signaling and Myofibroblast Transformation in Mouse Cardiac Fibroblasts
    Circulation Research, 102:185-192, 2008.

  7. Shonsey, E.M., Eliuk, S.M., Kirk, M.C. Barnes, S., Falany, C.N., Renfrow, M.B.
    Inactivation of Human Liver Bile Acid CoA:Amino Acid N-acyltransferase by the Reactive Aldehyde, 4-Hhydroxynonenal.
    Journal of Lipid Research, 49:282-294, 2008.

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2007

  1. Novak, J., Moldoveanu, Z., Renfrow, M.B, Yanagihara, T., Suzuki, H., Raska, M., Hall, S., Brown, R., Huang, W.-Q., Goepfert, A., Kilian, M., Poulsen, K., Tomana, M., Wyatt, R.J., Julian, B.A., Mestecky, J.
    IgA Nephropathy and Henoch-Schoenlein Purpura Nephritis: Aberrant Glycosylation of IgA1, Formation of IgA1-Containing Immune Complexes, and Activation of Mesangial Cells.
    Contrib Nephrol. 157:134-8, 2007.

  2. Renfrow, M.B., Mackay, C.L., Chalmers, M.J., Julian, B.A., Mestecky, J., Kilian, M., Poulsen, K., Emmett, M.R., Marshall, A.G., Novak, J.
    Analysis of O-glycan Heterogeneity in IgA1 Myeloma Proteins by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry: Implications for IgA Nephropathy.
    Anal. Bioanal. Chem. 389:1397-407, 2007.

  3. Eliuk SM, Renfrow MB, Shonsey EM, Barnes S, Kim H.
    Active Site Modifications of the Brain Isoform of Creatine Kinase by 4-Hydroxy-2-nonenal Correlate with Reduced Enzyme Activity: Mapping of Modified Sites by Fourier Transform-Ion Cyclotron Resonance Mass Spectrometry.
    Chem Res Toxicol. Sep;20(9):1260-8, 2007.

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2006

  1. Zürbig, P., Renfrow, M. B., Schiffer,E., Novak J., Walden M., Wittke, S., Matthias Pelzing, M., Neusüβ, C., Theodorescu, D., Root, K.E., Ross, M.M., Mischak, H.
    Biomarker discovery by CE-MS enables sequence analysis via MS/MS with platform-independent separation.
    Electrophoresis. June;27, 2111-25, 2006.

  2. Renfrow MB, Cooper HJ, Tomana M, Kulhavy R, Hiki Y, Toma K, Emmett MR, Mestecky J, Marshall AG, Novak J.
    Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation fourier transform-ion cyclotron resonance mass spectrometry.
    J Biol Chem. 280:19136-19145, 2005.

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2005

  1. Kang S, Prevelige PE Jr.
    Domain study of bacteriophage p22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange.
    J Mol Biol. 347:935-948, 2005.

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2004

  1. Lanman J, Lam TT, Emmett MR, Marshall AG, Sakalian M, Prevelige PE Jr.
    Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange.
    Nat Struct Mol Biol. 11: 676-677, 2004.

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2003

  1. Lanman, J, Lam, TT, Barnes, S, Sakalian, M, Emmett, MR, Marshall, AG, Prevelige Jr., P.E.
    Identification of Novel Interactions in HIV-1 Capsid Protein Assembly by High-resolution Mass Spectrometry.
    J. Mol. Biol. 325:759, 2003.

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2002

  1. Lam, T., Lanman, J.K., Emmett, M.E., Hendrickson, C.L., Marshall, A.G., Prevelige Jr. P.E.
    Mapping of protein:protein contact surfaces by hydrogen/deuterium exchange, followed by on-line high-performance liquid chromatography-electrospray ionization Fourier-transform ion-cyclotron-resonance mass analysis.
    J Chromatogr A. Dec 20;982(1):85-95, 2002.