Pilot Projects
Pilot grants funded in 2008:
| Pilot study : |
Polyphenols from botanicalson the activity of the Sir2 family of evolutionarily conserved NAD+ dependent deacetylases
(Ann Kirchmaier, Purdue) |
| Pilot study : |
Analysis of the actions of grape seed extract on neurogenesis in the yound adult rodent brain
(Linda Wadiche, UAB) |
Pilot grants funded in 2007:
| Pilot study 1: |
The pharmacokinetics and bioavailability of herbal remedies used by rural
African-Americans. (Glenda L. Smith, UAB) |
| Pilot study 2: |
Isoflavone dependent modulation of the vascular glycocalyx during inflammation.
(Rakesh P. Patel, UAB) |
| Pilot study 3: |
Effects of mannan on body weight and body composition: a precursor to
a longevity study. (David
B. Allison, UAB) |
| Pilot study 4: |
Chemoprevention of colon carcinogenesis by dietary and medicinal mushrooms
(David Sliva/Jiri Adamec, Purdue) |
Pilot grants funded in 2006:
| Pilot study 1: |
Gamma Tocopherol as a novel chemoprevention agent in azoxymethane-induced
colon cancer model (Qing Jiang, Purdue) |
| Pilot study 2: |
Green Tea Formulations for Amelioration of Type 2 Diabetes in the Zucker
Diabetic Rat Model with NMR Evaluation of Disease Progress (Elsa
M. Janle, Purdue) |
| Pilot study 3: |
Efficacy of Grape Seed Extract in Protection Against Vascular Calcification
in a Model of Uremia (K. Wilund, Purdue) |
Pilot grants funded in 2005:
| Pilot study 1: |
Digestive fate of tea catechins: impact of tea fromulation on catechin
digestive recovery and human intestinal cell uptake (Mario
Ferruzzi, Purdue)
|
| Pilot study 2: |
Neuroprotective effect of blueberry extract on Parkinson Disease
(Chris Rochet, Purdue)
|
Pilot grants funded in 2004:
| Pilot study 1: |
Beneficial
Effects of Soy Isoflavonoids on Prevention of Age-related Ocular Damage
in Monkey (Chao-Chen
Wang, UAB)
|
| Pilot study 2: |
Interactions between green tea polyphenols and intestinal
xenobiotic transporters (David Forster, IUPUI)
|
| Pilot study 3: |
Chemo-preventive Effects of Cranberry Juice Concentrate
on Urinary Bladder carcinogenesis (Clinton Grubbs,
UAB) |
Pilot grants funded in 2003:
| Pilot study 1: |
Effect of green tea extract of alcohol-induced mitochondrial
dysfunction: a proteomics approach (Shannon M. Bailey, UAB)
|
| Pilot study 2: |
Genistein-mediated prostate cancer prevention through enhanced
vitamin D signaling (Jim
Fleet, Purdue) |
| Pilot study 3: |
Soy isoflavones in fat cell gene regulation (Young-Cheul
Kim, Purdue) |
| Pilot study 4: |
Evaluation of telomerase mechanisms in human breast cancer cells after
treatment with the polyphenol EGCG (Trygve
Tollefsbol, UAB) |
Pilot grants funded in 2002:
| Pilot study 1: |
Pinitol Supplementation in humans: Effects on blood and
urine inositol concentrations and whole body and muscle glucose metabolism
(Wayne
Campbell, Purdue ). |
| Pilot study 2: |
Oxidation of Kava by Human Cytochrome P450 2D6 Causes Hepatotoxicity
(Luke Lightning, Purdue ). |
| Pilot study 3: |
Bioavailability and molecular targets identification of
Isoflavones from Kudzu dietary supplements (Jeevan
Prasain, UAB ). |
| Pilot study 4: |
Do Phytochemicals used to promote Prostate Health have
beneficial or detrimental effects on lethal cancer progression? (David
Walters, Purdue ) |
Pilot grants funded in 2001:
| Pilot study 1: |
Prevention of cutaneous photoageing by dietary botanical
supplements
(Santosh Katiyar, UAB) |
| Pilot study 2: |
Grape seed extract efficacy in a model of hypertension
(J.
Michael Wyss, UAB) |
| Pilot study 3: |
Modulation of monocyte-endothelial cell interactions by polyphenols
(Rakesh Patel, UAB) |
| Pilot study 4: |
Effect of green tea on glucose tolerance in rats and prevention
of diabetes in Zucker diabetic rats: (Elsa Janle, Purdue) |
|