Purdue University-University of Alabama at Birmingham

Botanicals Center for Dietary Supplements Research

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Joint Seminar on Chinese Medicine (Flyer)
UAB in cooperation with Samford University School of Medicine welcomes two distinguished scholars of Chinese Medicine to Birmingham. Read more.

Pilot Projects

Pilot grants funded in 2008:

Pilot study : Polyphenols from botanicalson the activity of the Sir2 family of evolutionarily conserved NAD+ dependent deacetylases (Ann Kirchmaier, Purdue)
Pilot study : Analysis of the actions of grape seed extract on neurogenesis in the yound adult rodent brain (Linda Wadiche, UAB)

Pilot grants funded in 2007:

Pilot study 1: The pharmacokinetics and bioavailability of herbal remedies used by rural African-Americans. (Glenda L. Smith, UAB)
Pilot study 2: Isoflavone dependent modulation of the vascular glycocalyx during inflammation. (Rakesh P. Patel, UAB)
Pilot study 3: Effects of mannan on body weight and body composition: a precursor to a longevity study. (David B. Allison, UAB)
Pilot study 4: Chemoprevention of colon carcinogenesis by dietary and medicinal mushrooms (David Sliva/Jiri Adamec, Purdue)

Pilot grants funded in 2006:

Pilot study 1: Gamma Tocopherol as a novel chemoprevention agent in azoxymethane-induced colon cancer model (Qing Jiang, Purdue)
Pilot study 2: Green Tea Formulations for Amelioration of Type 2 Diabetes in the Zucker Diabetic Rat Model with NMR Evaluation of Disease Progress (Elsa M. Janle, Purdue)
Pilot study 3: Efficacy of Grape Seed Extract in Protection Against Vascular Calcification in a Model of Uremia (K. Wilund, Purdue)

Pilot grants funded in 2005:

Pilot study 1: Digestive fate of tea catechins: impact of tea fromulation on catechin digestive recovery and human intestinal cell uptake (Mario Ferruzzi, Purdue)
Pilot study 2: Neuroprotective effect of blueberry extract on Parkinson Disease (Chris Rochet, Purdue)

Pilot grants funded in 2004:

Pilot study 1: Beneficial Effects of Soy Isoflavonoids on Prevention of Age-related Ocular Damage in Monkey (Chao-Chen Wang, UAB)
Pilot study 2: Interactions between green tea polyphenols and intestinal xenobiotic transporters (David Forster, IUPUI)
Pilot study 3: Chemo-preventive Effects of Cranberry Juice Concentrate on Urinary Bladder carcinogenesis (Clinton Grubbs, UAB)

Pilot grants funded in 2003:

Pilot study 1: Effect of green tea extract of alcohol-induced mitochondrial dysfunction: a proteomics approach (Shannon M. Bailey, UAB)
Pilot study 2: Genistein-mediated prostate cancer prevention through enhanced vitamin D signaling (Jim Fleet, Purdue)
Pilot study 3: Soy isoflavones in fat cell gene regulation (Young-Cheul Kim, Purdue)
Pilot study 4: Evaluation of telomerase mechanisms in human breast cancer cells after treatment with the polyphenol EGCG (Trygve Tollefsbol, UAB)

Pilot grants funded in 2002:

Pilot study 1: Pinitol Supplementation in humans: Effects on blood and urine inositol concentrations and whole body and muscle glucose metabolism (Wayne Campbell, Purdue ).
Pilot study 2: Oxidation of Kava by Human Cytochrome P450 2D6 Causes Hepatotoxicity
(Luke Lightning, Purdue ).
Pilot study 3: Bioavailability and molecular targets identification of Isoflavones from Kudzu dietary supplements (Jeevan Prasain, UAB ).
Pilot study 4: Do Phytochemicals used to promote Prostate Health have beneficial or detrimental effects on lethal cancer progression? (David Walters, Purdue )

Pilot grants funded in 2001:

Pilot study 1: Prevention of cutaneous photoageing by dietary botanical supplements
(Santosh Katiyar, UAB)
Pilot study 2: Grape seed extract efficacy in a model of hypertension (J. Michael Wyss, UAB)
Pilot study 3: Modulation of monocyte-endothelial cell interactions by polyphenols (Rakesh Patel, UAB)
Pilot study 4: Effect of green tea on glucose tolerance in rats and prevention of diabetes in Zucker diabetic rats: (Elsa Janle, Purdue)