chattopadhyay


Debasish Chattopadhyay, Ph.D.
Professor, School of Medicine

Areas of focus: Protein Structure Based Drug Discovery, Host Pathogen Interaction, Vaccine Design

Publications


Visit Debasish's Lab
 


Research interests

My research is devoted to develop an understanding of how various pathogens infect their hosts and cause diseases. Using a variety of biochemical and biophysical tools including single crystal X-ray crystallography we analyze the molecular mechanisms involved in infection and invasion of the host by the pathogen and survival and growth of the pathogen within the host. A thorough understanding of these mechanisms may have direct impact on the development of therapeutic strategies, therapeutic and diagnostic tools. Current research projects in the lab target the following pathogens: Plasmodium, the malaria parasites; Trypanosoma cruzi, the parasite which causes Chagas’ disease; gram positive bacterium Streptococcus pneumonia and Streptococcus agalactiae; smallpox virus (Vaccinia).