The Center for Structural Biology’s (CSB) mission is to support UAB faculty (currently across 8 schools), undergraduate, graduate and post-graduate students whose research will benefit from 1) the academic pursuit of structure/function relationships for biological macromolecules, 2) the utilization of structure-based methodologies for drug discovery initiatives 3) acquisition and/or development of new structural biology technologies and 4) coordination between the College of Arts and Sciences (CAS) and Graduate Biomedical Sciences (GBS) structural biology programs. The CSB will support collaborative extramural multi-investigator and individual research programs, provide student training in structural biology and engage in educational outreach initiatives.

The Center for Structural Biology Facility consists of multiple service centers:

  1. High throughput Nano-Crystallization Screening
  2. Self-Interaction Chromatography (SIC) Measurements
  3. Biomolecular Analysis (Differential Scanning Calorimetry and Isothermal Titration Calorimetry)
  4. Biacore
  5. X-Ray Crystallography (X-Ray Diffraction and 3D structure Determination)
  6. Cryo-Electron Microscopy
  7. Nuclear Magnetic Resonance
  8. SERCAT - Access to the Argonne National Laboratory, Synchrotron through SERCAT (Southeastern Collaborative Access Team)