Cilia and Cystic Kidney Disease Related Cell Lines Available from Core B

Line Name

Gene

Tissue

Mouse Model

Status

Special Features

94DpcDNA, 94DBap737- Rescue 1 and 2)

IFT88 and Rescue

Kidney Collecting Duct

ORPK ImmortoMouse Kidney

Available

Mutant and Rescue

BY-176

Kif3a Conditional Mutant Collecting Duct

Kidney Collecting Duct

Kif3a Flox Cagg-CreER, ImmortoMouse

Available

Tamoxifen Inducible Cre 
(Cre leaky)

BY-2574

IFT88 Conditional Mutant

Kidney Collecting Duct

IFT88 Flox Cagg-CreER, ImmortoMouse

In Quality Control

Tamoxifen Inducible Cre 
(Cre leaky)

BY -8827

IFT88 Conditional Mutant

Kidney

IFT88Flox; ImmortaMouse,

In Quality Control

(No Cre)

BY-1106

IFT88 Flox 

Kidney Collecting Duct

IFT88 Flox ImmortoMouse

Available

Cre Inducible Mutant and Control Line

BY-2847

IFT88 Conditional Mutant Embryonic Fibroblast

Mouse embryo E14.5 Embryo

IFT88 Flox Cagg-CreER, ImmortoMouse

In Quality Control

Cre Inducible Mutant and Control Line 
(Cre leaky)

BY6358

IFT88 Conditional Mutant Embryonic Fibroblast

Mouse embryo E14.5 Embryo

IFT88 Flox ImmortoMouse

In Quality Control

(No Cre)

BY-4976

IFT88 Conditional Mutant

Renal epithelium

IFT88 Flox Cagg-CreER, ImmortoMouse

In Quality Control

Tamoxifen Inducible Cre 
(Cre leaky)

MKS6

MKS6 delta

MEF

Gene Trap

Available

Non ciliated

B9D1

B9D1  delta

MEF

Deleted line

Available

Non ciliated

Rabl5

Rabl5 delta

MEF

Deleted line

In Quality Control

Ciliated

Rabl4

Rabl4  delta

MEF

Deleted line

In Quality Control

Ciliated

Traf3ip

Traf3ip delta

MEF

Deleted line

In Quality Control

Non ciliated

GAS8

Gas8 delta

MEF

Deleted line

In Quality Control

Ciliated

IMCD-SSTR3-GFP

SSTR3GFP

IMCD

NA

Available

Cilia marker

SSTR3-GFP ES

Mouse ES cells 
SSTR3-GFP ES in ROSA Locus

Embryonic Stem Cell

NA

Available

Cre inducible cilia tag