The Lupus Research Alliance recently awarded UAB a one-year grant of $250,000 to investigate a new explanation for how lupus develops and the reason some people, particularly African-Americans, are at a greater risk for flare-ups and kidney disease.
Genetic changes that protected their ancestors against fly-borne parasites may partly explain why African-Americans with lupus are up to five times more likely to develop end-stage kidney disease than those of European descent. This was the conclusion of a study presented this week at the American College of Rheumatology Scientific Sessions in Washington, D.C.