Instructor of Medicine

Division of Clinical Immunology and Rheumatology

Address:

Shelby Building, Room 277
1825 University Boulevard
Birmingham, AL 35294

Telephone: (205) 934-5095

Fax: (205) 934-0515

Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Education:

B.Sc (Biochemistry): Shandong University, Jinan, China, 1994
M.Sc. (Molecular Biology): Institute of Biophysics, Chinese Academy of Sciences, China, 1997
Ph.D. (Environmental Health Sciences): University of Alabama at Birmingham, 2006
Postdoctoral Fellow: Department of Pathology, University of Alabama at Birmingham, 2006-2011

Research Interests

Mechanisms by which Mycoplasma/Ureaplasma species interact with the host to avoid or subvert host defense.

Selected Publications

Xiao L, Crabb DM, Duffy LB, Paralanov V, Glass JI, Waites KB. 2012. Chromosomal mutations responsible for fluoroquinolone resistance in Ureaplasma species in the United States. Antimicrobial Agents and Chemotherapy. 56(5):2780-3. PMID:22371892

Paralanov V, Duffy LB, Crabb DM, Shrisastava S, Methe B, Inman J, Yooseph S, Xiao L, Lu J, Cassell GH, Waites KB, Glass JI. 2012. Comparative genome analysis of 19 Ureaplasma urealyticum and Ureaplasma parvum strains. BMC Microbiol. 12(1):88. PMID:22646228

Waites KB, Xiao L, Paralanov V, Viscardi RM, Glass JI. 2012. Molecular methods for the detection of Mycoplasma and Ureaplasma infections in human. The Journal of Molecular Diagnostics. 14(5):437-50. PMID:22819362

Xiao L, Crabb DM, Duffy LB, Paralanov V, Glass JI, Hamilos DL, Waites KB. 2011 Mutations in ribosomal proteins and ribosomal RNA confer macrolide resistance in human Ureaplasma species. Internat J Antimicrob Agents, 37(4):377-9. PMID:21353494

Xiao L, Paralanov V, Glass JI, Duffy LB, Robertson JA, Cassell GH, Chen Y, Waites KB. 2011 Extensive horizontal gene transfer in ureaplasmas from humans questions the utility of serotyping for diagnostic purposes. J Clin Microbiol. 49(8):2818-26. PMID: 21697330

Xiao L, Crabb DM, Moser SA, Duffy LB, Glass JI, Paralanov V, Waites KB. 2011 Genotypic characterization of Ureaplasma serovars from clinical isolates by pulsed-field gel electrophoresis. J Clin Microbiol. 49(9):3325-8. PMID: 21795510

Lu X, Xiao L, Wang L, Ruden DM. 2011. Hsp90 inhibitors and drug resistance in cancer: The potential benefits of combination therapies of Hsp90 inhibitors and other anti-cancer drugs. Biochem Pharmacol. 83(8):995-1004. PMID:22120678

Waites KB, Xiao L, Paralanov V, Glass JI. 2011 Ureaplasma. p. 469-487. In Liu D (ed.) Molecular detection of human bacterial pathogens. CRC Press, Boca Raton, FL, USA

Okogbule-Wonodi AC, Gross GW, Sun CC, Agthe AG, Xiao L, Waites KB, Viscardi RM. 2011. Necrotizing enterocolitis is associated with ureaplasma colonization in preterm infants. Pediatr Res. 69(5 Pt 1):442-7. PMID: 21258263

Xiao L, Glass JI, Paralanov V, Yooseph S, Cassell GH, Duffy LB, Waites KB. 2010. Detection and characterization of human Ureaplasma species and serovars by real-time PCR. J Clin Microbiol. 48(8):2715-23. PMID:20554828  PMCID:PMC2916572