NExTNet Vision
To transform biomedical research, clinical care and, ultimately, global health by providing the evidence base that will optimize exercise prescription and lifestyle intervention strategies in a disease-specific and population-specific manner.NExTNet Mission Statement
To achieve its vision, NExTNet will lead and facilitate rigorous, multi-institutional, trans-disciplinary research to address key knowledge gaps in:Exercise Biology
• Mechanisms driving dose-response relationships.• Genetic and phenotypic variations in responsiveness.
• Mechanisms by which physical inactivity fosters development and progression of CNCDs.
• Taking advantage of the potent exercise stimulus to discover new pathways and molecular targets.
Exercise-Drug/Device Interactions
• Differences in drug/device efficacy between active and inactive individuals.• Synergism, antagonism, drug metabolism.
• Drug re-purposing based on exercise responses.
