May 22, 2014

IL-1 the Culprit in Juvenile Arthritis?

"Systemic JIA is likely best classified as an autoinflammatory disease, based upon the robust clinical response to IL-1 inhibition and the absence of known autoantibodies, autoreactive T-cells, or association with HLA genotypes," explained Timothy Beukelman, MD, of the University of Alabama at Birmingham, who was a co-author of the updated ACR guidelines.

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