Jeff Hansen
| This email address is being protected from spambots. You need JavaScript enabled to view it.Research Editor
jeffhans@uab.edu • (205) 209-2355Communicates UAB research discoveries and initiatives from across the university for a variety of audiences.
Specific beats include: biochemistry; cell, developmental and integrated biology; microbiology; molecular genetics; neurobiology; pathology; pharmacology and tocixology; Alabama Drug Discovery Alliance; Bill L. Harbert Institute for Innovation and Entrepreneurship.
UAB researchers discover a new protein interaction from the 1918 flu strain that may help influenza circumvent the host immune response that would fight viral infection.
Famed neuroscientist Roger Nicoll, Ph.D., recently came to UAB to explain how he prevailed over great challenges in his life. Grad students in UAB’s Neuroscience Roadmap Scholars Program appreciated that, because they face challenges too. Learn about Nicoll’s tear-inducing speech, and the groundbreaking Roadmap program for underrepresented students, in The Mix.
An Arizona drug company will patent the small peptide drug.
Until now, no toxin had been found in 132 years of study for the deadly pathogen Mycobacterium tuberculosis, which infects 9 million people a year and kills more than 1 million. The novel toxin induces necrotic cell death of macrophages to help the tuberculosis pathogen escape and spread to other cells.
The challenge is to stifle the binding of inhibitory antibodies but retain activity of a blood enzyme.
The mimicry of bone cells by multiple myeloma is driven by overexpression of Runx2, the master regulator of bone formation.
The drug inhibits the activity of a kinase enzyme called LRRK2, and it showed no pathology in rat lungs, kidneys or livers.
The intensive intervention was four hours a day, five days a week, for a total of 200 hours of face-to-face instruction, and neuroimaging revealed brain connectivity changes. 
Macrophage cells require agility to scavenge and digest dead cells and prevent an immune response to self. In lupus, the macrophages lose that agility.
This improvement in cognition persists despite a high-glycemic-index diet, a possible risk factor for Alzheimer’s.