Research & Innovation
Suzanne Judd, Ph.D., an epidemiologist at UAB, explains what will lead to herd immunity and why it is important to remain vigilant in reducing the spread of COVID-19.

Preclinical tests at UAB last year showed potent systemic and mucosal immune responses in mice after a single intranasal dose. The vaccine candidate was developed by Maryland-based Altimmune Inc.

To date, 33 percent of vaccine doses administered by UAB have gone to underrepresented communities, with almost 21 percent to Black Alabamians.
Innovation is widely regarded as one of the most important sources of sustainable competitive advantage in an increasingly changing environment.
Research found that gaining community members’ perspectives to identify barriers and facilitators to COVID-19, related to prevention, coping and testing, may potentially improve outcomes.
Altered epigenetic marks on ribosomal RNAs appear to create a pool of specialized ribosomes that can differentially regulate translation of specific messenger RNA.
In a new study from UAB, researchers found that eating grapes can protect skin from acute and chronic UV damage.
Ben McManus’ proposal to research the understudied relationship between resident well-being and work organization factors wins a distinguished NIOSH K01 grant.
PAGER-CoV offers a data-driven, precision medicine approach to help researchers around the world better understand COVID-19.
The 72-year-old patient was unable to mount her own immune defense against the SARS-CoV-2 virus because of chronic lymphocytic leukemia, which compromises normal immunity and immunoglobulin production.
If these hollow capsules are modified to target a solid tumor, PET imaging and therapeutic ultrasound can be used to rupture them and release an anticancer drug at ground zero.
The study highlights the common host genetic factors that influence the composition of the human gut microbiome, a major factor in human health.
Use of the diabetes drug metformin — before a diagnosis of COVID-19 — was associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes.
This special issue of the Journal of Neuroscience Research puts a spotlight on research by women neuroscientists and the challenges and hurdles they face.
In advance of public vaccination, a quick and accurate COVID-19 antibody test will help determine the presence of neutralizing antibodies, the molecules that aid in protection against the virus.
Observational clinical research of COVID-19 patients can help clinicians better understand how the previously unknown SARS-CoV-2 virus acts, and findings from this research can better inform treatment and vaccine design.
The challenge focuses on understanding the relationships between health conditions, health disparities and social determinants of health at the county level that may bring a higher burden of illness or mortality due to COVID-19.
This potential preventive treatment for Crohn’s disease was tested on a mouse model and on immune-reactive T cells from patients with Crohn’s disease.
Streptococcus pneumoniae is an opportunistic pathogen that commonly infects young children and the elderly. This atlas will help researchers better understand how to treat these infections.
Meier-Gorlin syndrome is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities.
To date, RPB has awarded UAB $5,245,000 in grants, which helped bolster the department’s research activities, including the purchase of equipment, lab supplies, and salaries for new and existing research faculty.
The study examined trends in mortality due to chronic lower respiratory disease and investigated disparities in deaths due to CLRD between rural and urban areas across the United States.
A study conducted by UAB investigators has outlined that deaths due to mitral regurgitation are increasing in the United States since 2012, after a continuous decline for 14 years.
Further understanding is needed of the redox change called reductive stress and its impact on the onset and progression of neurodegeneration.
A local early-stage startup has been approved for low-cost, low-risk, non-invasive procedures for patients with chronic liver disease.
A recent grant to UAB researchers from a national organization will yield insight into telehealth and potentially increase patient access to rheumatic care.
Mutations in CHD7 cause severe birth defects known as CHARGE syndrome cases, which include severe and life-threatening heart malformations.
Maryland-based Altimmune Inc. has submitted an Investigational New Drug application to the U.S. Food and Drug Administration to commence a Phase 1 clinical study of its single-dose intranasal candidate.
The OHDRC Pilot Program facilitates emerging research ideas, explores new methodologies and approaches and facilitates transdisciplinary research as it relates to obesity-related health disparities.
The RADx-UP program is focused on addressing disparities in COVID-19 response in underserved and vulnerable populations.
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