Research & Innovation
Use of the diabetes drug metformin — before a diagnosis of COVID-19 — was associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes.
This special issue of the Journal of Neuroscience Research puts a spotlight on research by women neuroscientists and the challenges and hurdles they face.
In advance of public vaccination, a quick and accurate COVID-19 antibody test will help determine the presence of neutralizing antibodies, the molecules that aid in protection against the virus.
Observational clinical research of COVID-19 patients can help clinicians better understand how the previously unknown SARS-CoV-2 virus acts, and findings from this research can better inform treatment and vaccine design.
The challenge focuses on understanding the relationships between health conditions, health disparities and social determinants of health at the county level that may bring a higher burden of illness or mortality due to COVID-19.
This potential preventive treatment for Crohn’s disease was tested on a mouse model and on immune-reactive T cells from patients with Crohn’s disease.
Streptococcus pneumoniae is an opportunistic pathogen that commonly infects young children and the elderly. This atlas will help researchers better understand how to treat these infections.
Meier-Gorlin syndrome is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities.
To date, RPB has awarded UAB $5,245,000 in grants, which helped bolster the department’s research activities, including the purchase of equipment, lab supplies, and salaries for new and existing research faculty.
The study examined trends in mortality due to chronic lower respiratory disease and investigated disparities in deaths due to CLRD between rural and urban areas across the United States.
A study conducted by UAB investigators has outlined that deaths due to mitral regurgitation are increasing in the United States since 2012, after a continuous decline for 14 years.
Further understanding is needed of the redox change called reductive stress and its impact on the onset and progression of neurodegeneration.
A local early-stage startup has been approved for low-cost, low-risk, non-invasive procedures for patients with chronic liver disease.
A recent grant to UAB researchers from a national organization will yield insight into telehealth and potentially increase patient access to rheumatic care.
Mutations in CHD7 cause severe birth defects known as CHARGE syndrome cases, which include severe and life-threatening heart malformations.
Maryland-based Altimmune Inc. has submitted an Investigational New Drug application to the U.S. Food and Drug Administration to commence a Phase 1 clinical study of its single-dose intranasal candidate.
The OHDRC Pilot Program facilitates emerging research ideas, explores new methodologies and approaches and facilitates transdisciplinary research as it relates to obesity-related health disparities.
The RADx-UP program is focused on addressing disparities in COVID-19 response in underserved and vulnerable populations.
UAB researchers led a large multiple-country study and used advanced machine learning techniques for risk prediction of neonatal deaths. The study reveals that low weight among newborn infants is associated strongly to most deaths in underdeveloped settings and suggests how these deaths can be reduced.
Alabamians who download and use the GuideSafe™ app now have an added layer of information when traveling to help make smart, informed COVID-19 decisions.
A new multidisciplinary program within UAB Medicine will help evaluate patients who have recovered from COVID-19 but are still experiencing symptoms and link them to the specialized care they need.
The company will focus on the invention, creation and monetization of proprietary medical technologies to solve major health challenges.
This finding and further studies could help treat strabismus, a condition in which the eyes do not properly align with each other while looking at an object.

Investigators are developing a telemedicine program to reduce vaccine hesitancy related to HPV and the novel coronavirus for adolescents in rural Alabama.

To better understand how COVID-19 affects a pregnant woman and her baby, researchers at UAB are enrolling patients in two studies to determine the short- and long-term impacts.
A study conducted by UAB investigators has outlined that deaths due to acute respiratory failure are increasing in the United States, and this disproportionately impacts Southern states and racial minorities.
Funding from the American Heart Association will help promote preventive attitudes regarding cardiovascular health through a virtual campaign.
As the country has grappled with an opioid crisis and with COVID-19, a third crisis has brewed. Suicide is now the 10th leading cause of death in the United States.
The train-the-trainers approach to moving scientific discovery to the marketplace adds 13 more training sites.
One participant said, “It seems like we’ve done 10 years of work in seven months!”
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