Research - News
Bacteria use molecular machines to move proteins, including toxins, across cell membranes. M. tuberculosis, which kills more than 1 million people a year, uses the ESX-4 type VII secretion system to transports its potent exotoxin.

Nearly 100,000 people in the United States have AE-IPF, and approximately 30,000 to 40,000 new cases are found each year.

Could superheroes make children participate in more dangerous play time? A UAB graduate research assistant is conducting a study to see whether superheroes could be related to adolescent injuries.

The study concluded that participants were hesitant to receive the COVID-19 vaccine due to mistrust, fear and lack of information.

The largest registry of U.S. children with cancer who were diagnosed with COVID-19 found an increased risk of having severe infection and having their cancer therapy modified because of COVID, underscoring the urgency of vaccinations for these children, the authors say.

The Hugh Kaul Precision Medicine Institute will help build the interface of the Biomedical Data Translator, a “virtual brain” that will host all biomedical data in the world. 

NIH selects UAB and UA as research sites for a longitudinal study on child development since pregnancy. 

The 10-week trial will include meals provided by study investigators.

Young cancer survivors are at higher risk of developing subsequent HPV-related cancers than the general population, but less likely to receive the HPV vaccine. Findings from the first clinical trial of its kind support making HPV vaccination a routine part of oncologic care for all young cancer survivors, researchers say.

A research grant provides opportunity to develop next-generation devices with application in quantum metrology, low-energy consumption spintronics and optoelectronic applications.
CORD will develop educational modules for students in grades 4 through 6 in Perry County, Alabama, to equip students and their families with accurate information about COVID vaccines.
The partnership between UAB and Tuskegee will build a community of scientists committed to inclusive excellence.
A study conducted by UAB researchers found that using genetic information for choosing medical treatment after getting a heart stent reduces the risk of potentially fatal cardiovascular events.
UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.
About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.
The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.
The effort led by UAB is projected to receive $17 million from NIH to support up to four years of patient follow-up.
The life sciences fund will focus on development of early-stage UAB technologies and startup companies.

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

The collaboration puts UAB experts on the ground in Zambia to strengthen research and public health capacity and address major global health challenges.
UAB researchers will study psilocybin, a psychedelic compound, on its effects on smoking cessation.     

The NIH grant creates Multiple Chronic Disease Centers around the nation to target chronic disease in minority populations.

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
The new grant links UAB researchers with colleagues at two other institutions to search for ways to advance therapies from bench to bedside.
The K23 research project focuses on the adaptation of a behavioral physical activity intervention with peer support for women with HIV and co-occurring hypertension. 
New study from UAB women’s health, infectious diseases and pediatric experts show increase in morbidity and adverse outcomes in pregnant patients caused by the Delta variant.
The O’Neal Invests program funds UAB investigators starting new cancer-related projects to initiate key, preliminary work needed to enable competitive R01 applications from the NIH.
UAB public health researcher suggests new framework in tracking tobacco and nicotine use in adolescents in the United States.

Fecal-dominant donor microbes in the recipient patients after fecal microbe transplantation did not correlate with response to anti-PD-1 therapy.

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