Research - News
UAB researchers conducted a study in end-stage heart failure patients with cardiogenic shock that revealed that B-type natriuretic peptide levels were elevated in end-stage heart failure but did not predict clinical outcomes.
Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to future infections. They are key sentinels against subsequent viral variants.
The M.D./Ph.D. student has since moved on to clinical studies, but the research into possible drugs to treat Alzheimer’s disease continues.
The modified mRNA — delivered after experimental heart attacks — transiently allows heart muscle cells to proliferate, leading to reduced infarct size and improved heart performance compared to untreated animals.
While preventive treatment with vigabatrin delayed the onset and prevalence of infantile spasms in TSC infants, it had no impact on focal seizures, drug-resistant epilepsy, or improvement of cognitive and behavioral scores at 24 months.
UAB researchers make a case for utilizing telehealth technologies in the care of injured rural patients stating that teletrauma can improve access to trauma care for rural patients.
The study’s findings provide valuable insights into the role of diet composition in Type 2 diabetes management.
Rachel Smith, Ph.D., professor in the UAB School of Engineering and principal investigator in the Neural Signal Processing and Modeling lab, was recently awarded multiple grants to fund research in seizure onset localization.
Since 1985, the Coronary Artery Risk Development in Young Adults study has examined the factors that contribute to the development of cardiovascular disease to better understand the natural history of cardiovascular disease over the adult life course.
These results add an additional, mechanistic aspect to further explain how the decades-old blood pressure medication verapamil can preserve beta cell function in Type 1 diabetes patients by affecting the hormone insulin-like growth factor 1.
This is the first direct evidence that resident microbiota can have a significant impact on the establishment and pathology of infection by two different human-specific pathogens.
TCE is a known environmental risk factor for parkinsonism. UAB researchers will evaluate whether T cell activation caused by TCE exposure leads to cognitive decline.
Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells.
The new technology will allow for non-invasive assessments for dry eye disease and inform the development of new treatments.
Periodontal disease is one of the leading causes of tooth loss in adults and may be a risk factor in the development of Alzheimer’s disease.
In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative disease.
$46 million awarded by NIH to UAB and partners allows researchers to continue following participants enrolled in the national Multicenter Osteoarthritis Study.
The newly introduced kidney function equation has value in predicting heart failure comparable to the old equation but may reduce racial disparities by improving access to heart failure therapy among Black heart failure patients.
UAB is one of the seven institutions receiving multimillion renewal funding to advance its Cyber Corps program. The grant will support an integrated curriculum for training master’s students in both cybersecurity and artificial intelligence.
New research from UAB shows a possible link between poverty and a child’s possibility of having a relapse in their acute lymphoblastic leukemia.
Published results from two UAB studies found the duration of intermittent hypoxemia events and the presence and persistence of a patent ductus arteriosus after birth are two novel risk factors of BPD-PH in preterm infants.
The UAB study revealed that specific linguistic styles within influencer posts can enhance or diminish engagement with the content.
Earlier research suggests that the use of low-dose atropine drops plays a role in slowing the progression of myopia in children. However, new research co-led by experts in the UAB School of Optometry shows that may not be the case.
The University of Alabama at Birmingham has been awarded $456,786 from the National Science Foundation to fund the development of a 3D-printed high-entropy alloy superconductor.
Despite fewer drivers on the roads and fewer injuries per accident, fatal crashes in Alabama increased by 26 percent over the three years from 2020 through 2022.
Because hypertension and uncontrolled blood pressure are major risk factors for heart disease and stroke, achieving equity in heart and brain health in the United States cannot be reached without paying attention to social determinants of health, a study shows.
These nanowires, which can transport electrons to help a microbe make energy, were first described in a Geobacter bacteria; but now nanowires appear to be widespread in both bacteria and archaea prokaryotes.
This funding will be used to research multiple health conditions, including alcohol-related liver disease, Alzheimer’s disease, breast cancer, heart failure, inflammatory bowel disease and Zhu-Tokita-Takenouchi-Kim syndrome.
UAB researchers conducted a nationwide population-level study to assess the cardiovascular health in Asian American adults. Results revealed that cardiovascular health declined in foreign-born Asian Americans by 28 percent from 2011-2020.
Researchers used a mouse model and cutting-edge neurobiological techniques to show how psychological stress during adolescence alters neuronal functions in the brain, resulting in altered postpartum social behavior.
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