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UAB researchers determine that using genes to guide medication regimens after getting a heart stent improves outcomes

A study conducted by UAB researchers found that using genetic information for choosing medical treatment after getting a heart stent reduces the risk of potentially fatal cardiovascular events.
A study conducted by UAB researchers found that using genetic information for choosing medical treatment after getting a heart stent reduces the risk of potentially fatal cardiovascular events.

Making the case to improve outcomes for sickle cell disease

UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.
UAB’s Julie Kanter, M.D., says statewide surveillance programs for sickle cell disease can help facilitate progress to improve outcomes.

Hypoxia imaging and combination therapy aid immunotherapy treatment of solid tumors

Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.
Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.

New research shows most people are honest — except for a few

New research shows most people are honest — except for a few
About three-quarters of people were consistently honest, telling between zero and two lies per day. By contrast, a small subset of people averaged more than six lies per day and accounted for a sizable proportion of the lies, says researcher Timothy Levine, Ph.D.

UAB investigator funded as part of innovative Parkinson’s disease research network

The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.
The grant links researchers from different disciplines, institutions and locations to study basic mechanisms that contribute to Parkinson’s disease.

RECOVER post-COVID study to enroll participants from the Deep South

The effort led by UAB is projected to receive $17 million from NIH to support up to four years of patient follow-up.
The effort led by UAB is projected to receive $17 million from NIH to support up to four years of patient follow-up.

New life sciences fund announced to spur UAB innovation commercialization

The life sciences fund will focus on development of early-stage UAB technologies and startup companies.
The life sciences fund will focus on development of early-stage UAB technologies and startup companies.

Slow release of a drug, TT-10, improves heart attack recovery in a mouse model

Slow release of a drug, TT-10, improves heart attack recovery in a mouse model

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

ZAMBAMA grant leverages “reverse innovation” to reduce unhealthy alcohol use and improve HIV outcomes

UAB’s Julie Kanter, Ph.D., says population-wide surveillance programs can help to facilitate progress in treatment of sickle cell disease.
The collaboration puts UAB experts on the ground in Zambia to strengthen research and public health capacity and address major global health challenges.

UAB researcher granted federal funding for psilocybin and smoking study

UAB researcher granted federal funding for psilocybin and smoking study
UAB researchers will study psilocybin, a psychedelic compound, on its effects on smoking cessation.

UAB launches research collaboration to reduce disparities in chronic diseases in the Deep South

The NIH grant creates Multiple Chronic Disease Centers around the nation to target chronic disease in minority populations.

The NIH grant creates Multiple Chronic Disease Centers around the nation to target chronic disease in minority populations.

UAB researchers are part of a $3 million award to learn how to better treat lupus in Black patients

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.

UAB joins research network dedicated to improving treatments for brain tumors

UAB joins research network dedicated to improving treatments for brain tumors
The new grant links UAB researchers with colleagues at two other institutions to search for ways to advance therapies from bench to bedside.

UAB researcher awarded NIH grant to research peer support for women living with hypertension and HIV

Kaylee Crockette, Ph.D. has been awarded an NIH Grant. The K23 research project focuses on the adaptation of a behavioral physical activity intervention with peer support for women with HIV and co-occurring hypertension.
The K23 research project focuses on the adaptation of a behavioral physical activity intervention with peer support for women with HIV and co-occurring hypertension. 

Delta variant increases risk of adverse outcomes in pregnant women, new UAB study shows

New study from UAB women’s health, infectious diseases and pediatric experts show increase in morbidity and adverse outcomes in pregnant patients caused by the Delta variant.
New study from UAB women’s health, infectious diseases and pediatric experts show increase in morbidity and adverse outcomes in pregnant patients caused by the Delta variant.

Breast Cancer Research Foundation of Alabama supports O’Neal Invests with $400,000 in awards

The O’Neal Invests program funds UAB investigators starting new cancer-related projects to initiate key, preliminary work needed to enable competitive R01 applications from the NIH.
The O’Neal Invests program funds UAB investigators starting new cancer-related projects to initiate key, preliminary work needed to enable competitive R01 applications from the NIH.

Vaping up, cigarettes down in adolescents, according to study

UAB public health researcher suggests new framework in tracking tobacco and nicotine use in adolescents in the United States.
UAB public health researcher suggests new framework in tracking tobacco and nicotine use in adolescents in the United States.

Individual donor strains do not show link between fecal microbe transplantation and successful melanoma immunotherapy

Fecal-dominant donor microbes in the recipient patients after fecal microbe transplantation did not correlate with response to anti-PD-1 therapy.

Fecal-dominant donor microbes in the recipient patients after fecal microbe transplantation did not correlate with response to anti-PD-1 therapy.

Learning magic tricks can help self-esteem of kids with ADHD

Learning magic tricks can help self-esteem of kids with ADHD
The study, from UAB’s Institute for Arts in Medicine, shows that learning tricks in a magic camp can boost feelings of self-esteem and confidence in children and adolescents with disabilities.

Life expectancy, outcomes improving after BMT but still behind general population, study finds

Blood and marrow transplantation strategies have changed significantly over the past four decades; but recipients still experience excess mortality that translates into 8.7 years of life lost, according to researchers in UAB’s Institute for Cancer Outcomes and Survivorship.

Blood and marrow transplantation strategies have changed significantly over the past four decades; but recipients still experience excess mortality that translates into 8.7 years of life lost, according to researchers in UAB’s Institute for Cancer Outcomes and Survivorship.

$25 million grant renewal promotes access to health and wellness programs for those with disabilities nationwide

NCHPAD will utilize the grant, the largest in the history of the UAB School of Health Professions, to expand its role as a knowledge translation and implementation science/evaluation center to promote access to health and wellness programs for people with disabilities across the nation.
NCHPAD will utilize the grant, the largest in the history of the UAB School of Health Professions, to expand its role as a knowledge translation and implementation science/evaluation center to promote access to health and wellness programs for people with disabilities across the nation.

UAB trial studying diet composition — with no weight loss — to treat Type 2 diabetes

UAB trial studying diet composition — with no weight loss — to treat Type 2 diabetes

The study, led by Barbara Gower, Ph.D., is the first randomized clinical trial of a hypothesis that reducing fat stored around organs, through diet alone, can rescue beta-cell function.

Novel small molecule potently attenuates neuroinflammation in brain and glial cells

Limiting neuroinflammation may represent a promising new approach to treat neurological diseases driven by neuroinflammation, such as stroke, spinal cord injury and neuropathic pain.
Limiting neuroinflammation may represent a promising new approach to treat neurological diseases driven by neuroinflammation, such as stroke, spinal cord injury and neuropathic pain.

Should you skip breakfast? Eat dinner early? Is intermittent fasting good for you? Two UAB studies look for volunteers

Researchers are looking for people who either have Type 2 diabetes or are overweight to participate in the studies.
Researchers are looking for people who either have Type 2 diabetes or are overweight to participate in the studies.

UAB researchers find that 40 percent of young American adults have insulin resistance and cardiovascular risk factors

A study conducted by UAB researchers found that insulin resistance, a precursor to fatal cardiovascular events, is common among young adults.
A study conducted by UAB researchers found that insulin resistance, a precursor to fatal cardiovascular events, is common among young adults.

UAB’s Technology Innovation Center celebrates ribbon cutting, building opening

UAB’s Technology Innovation Center celebrates ribbon cutting, building opening
UAB’s Technology Innovation Center houses a state-of-the-art data center, the fastest university internet connectivity in the state, expandable technology infrastructure, and colocation for UAB’s partners in distributed IT.  

UAB awarded NIH telehealth grant to fight diabetes in the Deep South

The grant will explore ways to employ artificial intelligence with telehealth in rural, underserved areas of the South.
The grant will explore ways to employ artificial intelligence with telehealth in rural, underserved areas of the South.

The COVID-19 virus rapidly evolves to higher infectivity during in vitro growth, which may be a step toward lower virulence

The higher infectivity correlates with mutations that increase viral binding to a cell surface glucosaminoglycan, heparan sulfate.

The higher infectivity correlates with mutations that increase viral binding to a cell surface glucosaminoglycan, heparan sulfate.

Using translational pharmacogenomics to boost race-conscious medicine

Pharmacogenomics has become a valuable tool for optimizing treatments and is poised to play an increasing role in clinical care.

Pharmacogenomics has become a valuable tool for optimizing treatments and is poised to play an increasing role in clinical care.

Memory killer T cells are primed in the spleen during influenza infection

This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

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