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Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization

Lipid signaling from beta cells can potentiate an inflammatory macrophage polarization
This suggests the possibility of cross-talk that heightens pathogenesis in Type 1 diabetes.

Spending childhood, early adulthood in Stroke Belt increases risk of developing cognitive impairment later in life

Spending childhood, early adulthood in Stroke Belt increases risk of developing cognitive impairment later in life
People who spent their childhood or early adulthood in the Stroke Belt are more likely to develop cognitive impairment later, even if they have moved away.

Study shows new surgical protective gear does not reduce surgical site infections

Study shows new surgical protective gear does not reduce surgical site infections
New guidelines for operating room attire to prevent surgical site infections may be ineffective.

New pathogenic mechanism for influenza NS1 protein found

New pathogenic mechanism for influenza NS1 protein found
Influenza NS1 can bind with the cell’s RIG-I protein, blocking the innate immune response

New study calculates damage of food and lifestyle choices on inflammation

New study calculates damage of food and lifestyle choices on inflammation
A study of ice and fire: Research by UAB nutritional epidemiologist Suzanne Judd, Ph.D., and colleagues identified 19 foods and four lifestyle elements that raise or lower inflammation.

UAB injury study charts the unknown: Ultimate Frisbee

UAB injury study charts the unknown: Ultimate Frisbee
A UAB study of injury rates sustained by professional Ultimate players lays the groundwork for better understanding of injury risk as well as prevention strategies for the sport.

Holistic benefits of play in the classroom article among the journal’s best in 2019

Holistic benefits of play in the classroom article among the journal’s best in 2019

An article highlighting the importance of play in a child’s education and development selected as the 2019 Most Outstanding Article by journal.

How a community’s built environment impacts physical, mental health

How a community’s built environment impacts physical, mental health
Students are examining 60 variables, including sidewalk conditions, crosswalks, blighted properties and advertisements in four Birmingham communities.

Link between chronic kidney disease and heart failure is identified in patients

Link between chronic kidney disease and heart failure is identified in patients
Coronary microvascular dysfunction is a precursor to later heart disease, heart failure and possible death.

Study shows huge fluctuations in the cost of orthobiologics

Study shows huge fluctuations in the cost of orthobiologics
UAB orthopaedic surgeons report that the cost of orthobiologics, promising but not fully proven therapies, can vary widely across the nation.

Unrecognized genetic variation in research mouse models can affect immune cells

Unrecognized genetic variation in research mouse models can affect immune cells
Unsuspected genetic variation among strains of mice can surreptitiously confound data results.

Human fetal lungs harbor a microbiome signature

Human fetal lungs harbor a microbiome signature
This microbiome signature suggests that bacteria, or bacterial products, colonize the lungs far before birth.

Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling

Pathogenic Alzheimer’s disease cascade is activated by faulty norepinephrine signaling

Study points to a potential immediate treatment for this devastating disease.

Persistence of gut microbial strains in twins, living apart after cohabitating for decades

Persistence of gut microbial strains in twins, living apart after cohabitating for decades
A genomics tool can determine whether twins maintained identical gut strains, even after living apart for years.

Privacy alert: Brainwave devices can leak sensitive medical conditions and personal information

Privacy alert: Brainwave devices can leak sensitive medical conditions and personal information
Research results show that brain-computer interfaces is one source of caused leaked medical and personal information among particular individuals.

Cancer therapy may be aided by induced macropinocytosis, a rarely reported form of cell death

Cancer therapy may be aided by induced macropinocytosis, a rarely reported form of cell death

In preclinical experiments, a metabolic inhibitor killed a variety of human cancer cells of the skin, breast, lung, cervix and soft tissues.

75 million-year-old sea turtle fossil discovery is a new genus and species that sheds light on the evolution of its modern relatives

75 million-year-old sea turtle fossil discovery is a new genus and species that sheds light on the evolution of its modern relatives
Scientists are racing to determine which genealogy most accurately represents the evolutionary history of sea turtles — a challenging proposition.

Pediatric brain tumor treatment at UAB awarded FDA grant for first-in-human study

Pediatric brain tumor treatment at UAB awarded FDA grant for first-in-human study

A UAB pediatric oncologist will conduct a first-in-human immunovirotherapy study of an oncolytic herpes virus inoculated in the cerebellum.

Study yields new information about dementia’s genetic risk factors

Study yields new information about dementia’s genetic risk factors
Genome sequencing leads to new understanding of genetic risk factors that might play a role in the risk of dementia.

Undergraduate researchers win big for innovative ideas at research expo

Undergraduate researchers win big for innovative ideas at research expo
Alabama Power recognizes innovative student research with two $5,000 grants.

The smart-dumb question, a key to writing about — and understanding — immunology

The smart-dumb question, a key to writing about — and understanding — immunology
The UAB freshman immunology honors seminar recently held a Q&A with Pulitzer Prize-winning newspaper reporter Matt Richtel.

Novel sickle cell medication to help reduce pain crises, related hospitalizations

Novel sickle cell medication to help reduce pain crises, related hospitalizations

A UAB researcher’s involvement in clinical trials helped approve a first-of-its-kind targeted medication to reduce pain crisis for individuals with sickle cell disease.

Community members train doctors on culturally appropriate palliative care

Community members train doctors on culturally appropriate palliative care
Community members from Beaufort, South Carolina, trained palliative care physicians on how to have culturally appropriate conversations with their patients based on their backgrounds and ethnicities.

Novel bioprinter shows potential to speed tissue engineering

Novel bioprinter shows potential to speed tissue engineering

Engineered tissue from a bioprinter has promise for organ regeneration or replacement.

Nearly one-third of participants drop out of psychosocial substance use disorder treatments

Nearly one-third of participants drop out of psychosocial substance use disorder treatments
Researchers examined 50 years’ worth of data from studies that analyzed substance use disorder treatments.

Model probes possible treatments for neonatal infection, a common cause of infant death

Model probes possible treatments for neonatal infection, a common cause of infant death
Researchers found they could prevent deadly infections by giving the newborn mice specific protective bacteria.

Entrepreneurial student teams compete and solve real-world problems

Entrepreneurial student teams compete and solve real-world problems
Real-world problems are solved through a two-month entrepreneurship educational experience for students across UAB’s campus.

Study: Medical and surgical residents’ lack of sleep recovery leads to persistent fatigue

Study: Medical and surgical residents’ lack of sleep recovery leads to persistent fatigue

A new study shows the quality of sleep medical and surgical residents receive is poor and causes persistent fatigue throughout residency.   

A super cover illustration highlights superconductivity research

A super cover illustration highlights superconductivity research
Ilias Perakis commissioned an image to convey his terahertz-driven superconductivity.

Germ-free lungs of newborn mice are partially protected against hyperoxia

Germ-free lungs of newborn mice are partially protected against hyperoxia
A first-of-its-kind newborn mouse model will permit study of how to protect extremely low birth-weight infants from bronchopulmonary dysplasia, or BPD.  
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