Research - News
Researchers have been awarded a $2.6 million, four-year National Institutes of Health grant to evaluate a safer and more durable stent design, using techniques licensed through the UAB Harbert Institute for Innovation and Entrepreneurship by the UAB spinoff company Endomimetics LLC.
The monoclonal antibody cocktail is deliverable via a nasal dose, and it is also effective against SARS, MERS and several coronavirus cold viruses. The antibodies are engineered for long-acting effectiveness, potentially lasting a year or more when used in humans.
Reporting mental health records to national firearm background check system decreases suicide rates, according to research published by Collat School of Business professors.
The fields of neuroengineering and brain-computer interfaces could have a tremendous impact on a number of neurologic conditions, such as stroke, neurodegenerative disorders, Parkinson’s disease, dementia and other brain diseases.
Researchers hope to learn whether the immune system will respond to the experimental vaccines by making antibodies and T cells that could fight HIV if a person is ever exposed to the virus in the future.
Traditional markers of cardiometabolic health may be lower in Black individuals, but the development of diabetes is more common in those with African ancestry.
Benefits of the blood pressure medication verapamil include delayed disease progression, lowered insulin requirements and preservation of some beta cell function.
Student-led study shows that those with autism spectrum disorder present difficulties in time estimation abilities while driving.
More adolescents and young adults in the U.S. vape cannabis instead of nicotine, contradicting widely held beliefs of nicotine consumption in vaping.
The grant will fund research surrounding next-generation human models that could potentially aid in the development of treatment for glioblastoma.
As overall in-hospital cardiac arrest rates rise, overall survival rates are improving in tandem. But researchers say there is still room for improvement.
Blacks face much greater rates of heart disease than do whites. A wider study is needed to further investigate this racial difference and identify potential therapeutic targets.
UAB researchers are contributing to “Oral Health in America: Advances and Challenges,” a national publication aimed at exploring the nation’s oral health over two decades.
Anindya Dutta, M.D., Ph.D., and colleagues now have detailed the first structure-function study of this long non-coding RNA.
Although combination chemotherapy with radiation has been the standard of care for treating rectal cancer for more than 20 years, very little is known about why some tumors are more resistant to this treatment than others.
Southern Research has 400 full-time employees, brings in $80 million in revenue and has an annual economic impact of $150 million.
Throughout 2020, the decline in pediatric emergency department visits among Black and public or self-insured patients was consistently larger than other demographics.
UAB physicians are working on the next steps to begin compassionate or emergency use of the pig kidneys in living humans. Two major approvals will be required.
In response to a viral infection, intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling, leading to different fates for two subsets of those cells — the one producing IL-2 and the one not producing IL-2.
Consortium led by UAB researchers in the UAB Heersink School of Medicine and School of Public Health received additional funding to further study chronic hypertension and preeclampsia epigenetics participants enrolled in the CHAP trial.
A $200,000 grant for Magic City Data Collective will continue to build a diverse pipeline between students with data analysis skillets and local private-sector job opportunities.
Death or severe brain bleeding in the first week after birth dropped from 27.4 percent to 15 percent after introduction of a bundle of evidence-based, potentially better practices for preterm infants. Median weight of the 820 infants studied was 1 pound, 10 ounces.
The findings represent the first study to examine whether metabolic adaptation, at the level of Resting Metabolic Rate (RMR), is associated with time to reach weight-loss goals.
Early research internships allow students to discover careers of interest they may not otherwise experience, providing an effective way to set them up for success, study suggests.

A new study confirms that G207, a genetically engineered virus developed at UAB, may be a beneficial therapy for brain tumors.

Bibb has been studying neuroendocrine cancer for almost 10 years and has published several reports in high-impact scientific journals.
UAB is one of 14 institutions receiving funding for the Nutrition for Precision Health Study, part of the NIH’s All of Us Research Program.
The human preclinical model at UAB provides important knowledge before a Phase I clinical trial can begin for living human recipients. Decades of work by researchers across the world preceded UAB’s first clinical-grade pig kidney xenotransplant.

A detailed mechanistic study unravels how the bacterial endotoxin LPS prevents or promotes allergic disease.

UAB researcher explains why retailers prefer customers to keep purchased items instead of returning.
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