Gibson_2012Assistant Professor of Medicine



Shelby Bldg, Room 203
1825 University Blvd.

Telephone:(205) 975-6407

Fax:(205) 996-6734



BS (Biology), City University of New York, Brooklyn College, 1984
PhD (Genetics), City University of New York, Graduate School, 1995
MBA, American Intercontinental, Atlanta,GA, 2003
Postdoctoral Training, Cornell University Medical College/Hospital for Special Surgery, 1995-1996
Postdoctoral Training, University of Alabama at Birmingham, 1996-1999


Research Interests:

Molecular genetics and epigenetics of autoimmune diseases: Characterization of genetic variants on the SLE-linked q21-q42 region of chromosome 1; Structure and function of Fc gamma receptors in inflammation.



Click here for a more complete list of publications. Below are a few selected papers.

Shah S, Gibson AW, Ji C, Darrington E, Mobley J, Kojima K, Edberg JC, Kimberly RP. 2016. Regulation of FcRγ function by site-specific serine phosphorylation. J Leukoc Biol. 101(2):421-428. PMID: 27630214 PMCID: PMC5235907

Li X, Gibson AW, Kimberly RP. 2014. Human FcR polymorphism and disease. Curr Top Microbiol Immunol. 382:275-302. PMID: 25116105.

Absher DM, Li X, Waite LL, Gibson A, Roberts K, Edberg J, Chatham WW, Kimberly RP. 2013. Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 9(8):e1003678. PMID: 23950730 PMCID: PMC3738443

Li X, Baskin JG, Mangan EK, Su K, Gibson AW, Ji C, Edberg JC, Kimberly RP. 2012. The unique cytoplasmic domain of human FcγRIIIA regulates receptor-mediated function. J Immunol. 189(9):4284-94. PMID:23024279 PMCID:PMC3478424

Gibson AW, Li X, Wu J, Baskin JG, Raman C, Edberg JC, Kimberly RP. 2012. Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G. J Leukoc Biol. 91(1):97-103. PMID:22003208. Free PMC Article


Gibson AW, Li FJ, Wu J, Edberg JC, Su K, Cafardi J, Wiener H, Tiwari H, Kimberly RP, Davis RS. 2009. The FCRL3 -169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+B cells. Arthritis Rheum. 60(11):3510-2.  PMID: 19877046


Qian K, Xie F, Gibson AW, Edberg JC, Kimberly RP, Wu J. 2008. Functional expression of IgA receptor FcalphaRI on human platelets. J Leukoc Biol. 84(6):1492-500. PMID: 18784345


Wu J, Ji C, Xie F, Langefeld CD, Qian K, Gibson AW, Edberg JC, Kimberly RP. 2007. FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA. J Immunol. 178(6):3973-82. PMID: 17339498


Su K, Yang H, Li X, Li X, Gibson AW, Cafardi JM, Zhou T, Edberg JC, Kimberly RP. 2007. Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol. 178(5):3272-80. PMID: 17312177


Qin H, Edberg JC, Gibson AW, Page GP, Teng L, Kimberly RP. 2004. Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain. J Immunol. 173(10):6211-9. PMID: 15528358


Wu J, Metz C, Xu X, Abe R, Gibson AW, Edberg JC, Cooke J, Xie F, Cooper GS, Kimberly RP. 2003. A novel polymorphic CAAT/enhancer-binding protein beta element in the FasL gene promoter alters Fas ligand expression: a candidate background gene in African American systemic lupus erythematosus patients. J Immunol. 170(1):132-8. PMID: 12496392


Davis RS, Dennis G Jr, Odom MR, Gibson AW, Kimberly RP, Burrows PD, Cooper MD. 2002. Fc receptor homologs: newest members of a remarkably diverse Fc receptor gene family. Immunol Rev. 190:123-36. PMID: 12493010


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