Gibson, Andrew W., PhD

Gibson_2012Assistant Professor of Medicine


Address: 
 

Shelby Bldg, Room 203
1825 University Blvd. 
35294

Telephone:(205) 975-6407

Fax:(205) 996-6734
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Education

 

BS (Biology), City University of New York, Brooklyn College, 1984
PhD (Genetics), City University of New York, Graduate School, 1995
MBA, American Intercontinental, Atlanta,GA, 2003
Postdoctoral Training, Cornell University Medical College/Hospital for Special Surgery, 1995-1996

Postdoctoral Training, University of Alabama at Birmingham, 1996-1999


Research Interests:


Molecular genetics and epigenetics of autoimmune diseases: Characterization of genetic variants on the SLE-linked q21-q42 region of chromosome 1; Structure and function of Fc gamma receptors in inflammation.

 

Selected Publications


Li X, Baskin JG, Mangan EK, Su K, Gibson AW, Ji C, Edberg JC, Kimberly RP. 2012. The unique cytoplasmic domain of human FcγRIIIA regulates receptor-mediated function. J Immunol. 189(9):4284-94. PMID:23024279 PMCID:PMC3478424

Gibson AW, Li X, Wu J, Baskin JG, Raman C, Edberg JC, Kimberly RP. 2012. Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G. J Leukoc Biol. 91(1):97-103. PMID:22003208. Free PMC Article

 

Gibson AW, Li FJ, Wu J, Edberg JC, Su K, Cafardi J, Wiener H, Tiwari H, Kimberly RP, Davis RS. 2009. The FCRL3 -169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+B cells. Arthritis Rheum. 60(11):3510-2.  PMID: 19877046

 

Qian K, Xie F, Gibson AW, Edberg JC, Kimberly RP, Wu J. 2008. Functional expression of IgA receptor FcalphaRI on human platelets. J Leukoc Biol. 84(6):1492-500. PMID: 18784345

 

Wu J, Ji C, Xie F, Langefeld CD, Qian K, Gibson AW, Edberg JC, Kimberly RP. 2007. FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA. J Immunol. 178(6):3973-82. PMID: 17339498

 

Su K, Yang H, Li X, Li X, Gibson AW, Cafardi JM, Zhou T, Edberg JC, Kimberly RP. 2007. Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol. 178(5):3272-80. PMID: 17312177

 

Qin H, Edberg JC, Gibson AW, Page GP, Teng L, Kimberly RP. 2004. Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain. J Immunol. 173(10):6211-9. PMID: 15528358

 

Wu J, Metz C, Xu X, Abe R, Gibson AW, Edberg JC, Cooke J, Xie F, Cooper GS, Kimberly RP. 2003. A novel polymorphic CAAT/enhancer-binding protein beta element in the FasL gene promoter alters Fas ligand expression: a candidate background gene in African American systemic lupus erythematosus patients. J Immunol. 170(1):132-8. PMID: 12496392

 

Davis RS, Dennis G Jr, Odom MR, Gibson AW, Kimberly RP, Burrows PD, Cooper MD. 2002. Fc receptor homologs: newest members of a remarkably diverse Fc receptor gene family. Immunol Rev. 190:123-36. PMID: 12493010

 

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