AlarconJane Knight Lowe
Emeritus Professor of Medicine

 

Address: 

Faculty Office Towers, room 830
510 20th Street South
Birmingham, Alabama 35294-3408



Telephone:(205) 422-0983
Email: galarcon@uab.edu

 

Education


BS, Facultad de Ciencias, Universidad Nacional Mayor de San Marcos. Lima, Perú, 1961
MD, Facultad de Medicina, Universidad Peruana Cayetano Heredia. Lima, Perú, 1967
Fellowship (Clinical), Department of Medicine, Johns Hopkins University, School of Medicine. Baltimore City Hospitals, Baltimore, MD, 1969
Master in Public Health (M.P.H.), Johns Hopkins University, School of Hygiene and Public Health, Baltimore, MD, 1972
Doctor in Medicine, Universidad Peruana Cayetano Heredia. Lima, Perú, 1972
Fellowship (Research), Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, 1981

 

Selected Honors and Awards


1964, Diploma presented by the Peruvian Government recognizing voluntary work at the Sierra Indian Communities of Cuzco, Perú

1971-1972, Recipient of Merck, Sharp & Dohme Scholarship, Master of Public Health, Johns Hopkins University. Baltimore, MD

1980, American Rheumatism Association Senior Rheumatology Scholar Award

1988, Mexican Society of Rheumatology, Professor of the Year

1997, Virginia Engalichteff Award for Impact on Quality of Life, Arthritis Foundation. Denver, CO

2003, Outstanding Faculty-The University of Alabama at Birmingham Women's Center

2004, Pfizer Visiting Professor - Vanderbilt University- Nashville, TN

2006, Keynote Speaker,  Pan American League of Associations of Rheumatologists. Lima, Perú

2008, ACR Master, ACR Annual Scientifie Meeting, San Francisco, CA

2008, PANLAR Master, PANLAR Scientific Meeting, Guatemala City, Guatemala

2009, Dean's Award for Academic Execellence. The University of Alabama at Birmingham, Birmingham, Alabama

2000-2010, Visiting Professor, Argentinean Society of Rheumatology

2011, Mexican Society of Rheumatology: Honoring Latin American Masters of the American College of Rheumatology; Cancún, Mexico
         Speaker, Universidad Peruana Cayetano Heredia, 50th year Anniversary. Lima, Perú
         Evelyn Hess Award for Excellence in Lupus Research. Lupus Foundation of America. Chicago, IL

2012, Leader of Peruvian Rheumatology. Sociedad Peruana de Reumatología; Lima, Perú

2013, Visiting Professor. University of Washington; Seattle, WA.
          Dr. Honoris Causa. Universidad Nacional de Asunción; Asunción, Paraguay.
          Associate member, Peruvian Academy of Medicine

2014, Visiting Professor (38th Annual Michael Einbender Distinguished Lectureship. University Missouri; Columbus, MO
          American College of Rheumatology Distinguished Rheumatology Investigator Award, Boston, MA

2015, Peruvian College of Physicians: Recognition as Leader of Peruvian Rheumatology
         The Servicio de Inmuno-Reumatología, at Hospital Nacional Cayetano Heredia from Universidad Peruana Cayetano Heredia is named: Graciela S. Alarcón

2016, The University of Alabama at Birmingham establishes the Graciela S. Alarcón, MD, MPH Lupus Research Fund
          The Halsted R. Holman Award for Excellence on Clinical Research in Lupus. LUPUS 2016, Armonk, NY.
          Distinguished Service Award for promoting the goals of the Global Alliance for Musculoskeletal Health.

 

Clinical, Research and Education Interests


I joined the Faculty at UAB in 1981 after being a Research Fellow for about 18 months. I am currently Emeritus Professor and although not in Birmingham, I am still involved in mentoring fellows and collaborating with the LFA, LCTC, GLADEL as the need arises. During my stay at UAB and prior to that at my alma mater (Universidad Peruana Cayetano Heredia in Lima, Perú), I have been involved in the training of clinical and research fellows. In fact, after my US training (1968-1972), I started the first training program in Rheumatology and the first Rheumatology Unit in Perú. Whether in Perú or in the US, I have attended their clinics, have rounded with them, and foremost I have been stimulating them to always keep an open and inquisitive mind in dealing with their day-to-day activities being those in the clinic or in the research setting. I can say that over 60% of the fellows graduating from UAB between 1981 and the early 2000's, when I became more involved in the training of clinical research fellows (vide infra), have had the opportunity to publish their clinical experience under my mentorship and with my unconditional support. Of course, not all of them have become academicians or researchers in their own right, but I have been quick to point out to all of them that the proper appreciation of what research entails or the amount of work that goes into a published paper, can only come from personally going through the same experience.

Although I have been involved in mentoring Junior Faculty and clinical research fellows in the past, it has been only since 2002 that I have had the opportunity to LUMINAcollaboratorshave the funding to support them for the conduct of research in lupus. These fellows have used the very rich database from LUMINA, a multi-ethnic cohort of lupus patients established in collaboration with Drs. John Reveille (UT-Houston, TX) and Luis Vilá (U- Puerto Rico, San Juan, PR) in the early 1990's. Participating in the training of these young physicians while continuing to mentor Junior Faculty and clinical fellows, as time permits, has been, and continues to be, one of the most rewording but also challenging experiences of my academic life as a rheumatologist. For the most part, these trainees have come with limited research experience; despite that, they have performed spectacularly well. In addition to participating in data collection on patients from the cohort, they have generated their own sub-projects and taken them to completion including the Gladel 2publication of their findings in prestigious rheumatology journals. The fruits of LUMINA have been summarized in a special article published in the Journal Lupus in 2008. Moreover, the salient finding from the LUMINA study were highlighted in an article published in The Rheumatologist in the Spring of 2011. At the present time, I continue to be involved in the work of the fellows that trained with me over the last few years (Drs. Durán-Barragán, González, Pons-Estel and Burgos) who are conducting research in lupus in their country of origin. In parallel I am assisting the LCTC in the establishment of a national registry of lupus patients (US and Canada). Finally, over the last few years I have developed a very close relationship with GLADEL (for Grupo Latinoamericano de Estudio de Lupus or Latin American Group for the Study of Lupus), assisting them in the utilization of their rich database. This group with the support of PANLAR is now developing the Latin American treatment guidelines for lupus, effort in which I am quite involved.

 

Publications


Click here for a more complete list of publications. Below are selected papers


Ugarte-Gil MF, Pons-Estel GJ, Molineros J, Wojdyla D, McGwin G Jr, Nath SK, Pons-Estel BA, Alarcón-Riquelme M, Alarcón GS. 2016. Disease features and outcomes in United States lupus patients of Hispanic origin and their Mestizo counterparts in Latin America: A commentary. Rheumatology (Oxford). 55: 436-40. PMID: 26412809; PMC5009444


Petri M, Orbai AM, Alarcón GS, Gordon C, Merrill JT, Fortin PR, Bruce IN, Isenberg D, Wallace DJ, Nived O, Sturfelt G, Ramsey-Goldman R, Bae SC, Hanly JG, Sánchez-Guerrero J, Clarke A, Aranow C, Manzi S, Urowitz M, Gladman D, Kalunian K, Costner M, Werth VP, Zoma A, Bernatsky S, Ruiz-Irastorza G, Khamashta MA, Jacobsen S, Buyon JP, Maddison P, Dooley MA, van Vollenhoven RF, Ginzler E, Stoll T, Peschken C, Jorizzo JL, Callen JP, Lim SS, Fessler BJ, Inanc M, Kamen DL, Rahman A, Steinsson K, Franks AG Jr, Sigler L, Hameed S, Fang H, Pham N, Brey R, Weisman MH, McGwin G Jr, Magder LS. 2012. Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus. Arthritis Rheum 64: 2677-86. PMID: 22553077; PMC3409311


Shinjo SK, Bonfá E, Wojdyla D, Borba EF, Ramirez LA, Scherbarth HR, Brenol JC, Chacón-Diaz R, Neira OJ, Berbotto GA, De La Torre IG, Acevedo-Vázquez EM, Massardo L, Barile-Fabris LA, Caeiro F, Silveira LH, Sato EI, Buliubasich S, Alarcón GS, Pons-Estel BA; Grupo Latino Americano de Estudio del Lupus Eritematoso (Gladel). 2010. Antimalarial treatment may have a time-dependent effect on lupus survival: data from a multinational Latin American inception cohort. Arthritis Rheum. 62(3):855-62. PMID: 20131238


Burgos PI, Perkins EL, Pons-Estel GJ, Kendrick SA, Liu JM, Kendrick WT, Cook WJ, Julian BA, Alarcón GS, Kew II CE. 2009. Risk Factors and Impact of Recurrent Lupus Nephritis in Transplanted Patients with Systemic Lupus Erythematosus: Data from a Single US Institution. Arthritis Rheum 60:2757-66. PMID: 19714623; PMC2771574


Alarcón GS, McGwin G, Jr., Bertoli AM, Fessler BJ, Calvo-Alén J, Bastian HM, Vilá LM, Reveille JD, for the LUMINA Study Group. 2007. Effect of hydroxychloroquine in the survival of patients with systemic lupus erythematosus. Data from LUMINA, a multiethnic US cohort (LUMINA L). Ann Rheum Dis 66:1168-72. PMID: 17389655; PMC1955128

 

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