August 10, 2017

Seeking healthy participants with no history or diagnosis of mental illness

Seeking healthy participants with no history or diagnosis of mental illness personally or in a first-degree relative — mom, dad, sibling. You must not require medication to treat an existing physical or mental illness/disorder. Individuals abusing alcohol or recreational drugs cannot participate as there will be intensive drug screening — both urine and blood. You must be ages 18-55 and weigh less than 190 lbs. Participants are needed to evaluate the effect of a drug called LY2150023 (Pomaglumetad or "POMA" for short) on a naturally occurring chemical called glutamate in the brain. We will also ask you to receive an intravenous infusion of a drug called ketamine. Study requirements: Screening (visit 1): determine your eligibility for the study, about 2 hours and includes drug testing, a complete medical and neurological check-up; Screening Ketamine MRI (visit 2): drug testing, MRI scan and ketamine infusion to determine study eligibility; Study Day 1 (visit 3): take study medicine in clinic, clinic evaluation, blood draw about 2 hours; Study Day 5 (visit 4): Clinical evaluation, blood draw and checkup about 2 hours; Study 10 (visit 5): Clinical evaluation, blood draw, drug testing, MRI scan and ketamine infusion about 5-6 hours. Three follow up phone calls. As a participant you will receive: $50 for visits 1, 3 and 4; $100 for visit 2; $300 for completion of visit 5 for a total of $600. For further information about the study and your eligibility, please contact Kristen at 996-9813.
UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of race, national origin, age, genetic or family medical history, gender, faith, gender identity and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.