Research - News
UAB and Polish researchers propose that the COVID-19 virus acts as a microRNA “sponge” to deplete miRNA levels in ways that aid viral replication and stymie the host immune response.
This was the first study to evaluate the impact of exercise on objective sleep outcomes in persons with Parkinson’s disease.
This is the first comprehensive genomic study of cervical cancers in sub-Saharan Africa, with a focus on tumors from 212 Ugandan patients. The findings can lead to better treatments.
The pilot projects will yield payoffs down the road from the knowledge UAB researchers gain. Preliminary data from the pilots will form the basis for new grants and contracts, including pursuit of the $2 billion COVID-19 grant support being offered by the National Institutes of Health.
Women who had total body irradiation to prepare for blood or marrow transplantation before age 30 had a 4.5-fold increase in their risk of developing breast cancer later in life.
The two studies are part of a larger body of research attempting to solve the puzzle of racial disparities in pain.
A study conducted by UAB investigators shows that nearly a third of non-Hispanic Black young adults nationwide have hypertension, and the control of high blood pressure in all young adults is only 10 percent.
The drug candidate is a non-toxic small molecule that given orally effectively rescued mice from models of Type 1 and Type 2 diabetes.
This research offers fundamental insights about sensory thalamic subnetworks and will enable powerful new strategies to probe behavioral and perceptual functions of these distinct circuits.
When the I-20/59 corridor was dismantled and rebuilt over a 12-month period in 2019, it disrupted travel for more than 150,000 vehicles per day. UAB engineers are using data from that project to gain a better understanding of how drivers adapted.
The study will look at how the variability of different behaviors can affect quality of life.

AdCOVID stimulated both strong serum neutralizing activity and potent mucosal IgA immunity in the respiratory tract.

This work is a step forward in understanding early molecular changes that influence the development of addiction, and may have application to the role of similar gene programs that mediate other types of behavior, memory formation or neuropsychiatric disorders.

This study was done in mice and with a novel, tissue-engineered, three-dimensional breast cancer mimetic system.
This mouse study looked at a group of immune cells called innate-like B-1 B cells.
Genetic assessments can help predict the risk of common diseases, and UAB is part of a national study to better understand and implement polygenic risk scores
In partnership with community members, researchers at UAB created the first culturally based protocol for patients living with a serious illness or facing end-of-life care.
Higher-volume feedings were determined to help postnatal growth in preterm infants.
In a study led by a UAB neonatologist, findings showed that racial and ethnic disparities in preterm infants decreased.   
Exercise is good for you, but how does affect the very building blocks of your body?  UAB is poised to find out.
Doctors at UAB are now able to safely transplant organs from hepatitis C-positive donors into uninfected recipients and then treat the patients with antiviral therapy.
Injections of two chemicals in a slow-release form significantly reduced the size of dead heart tissue and improved the function of the left ventricle.
This novel finding will enable experimental studies to determine whether and how these microbes play a role in triggering the disease.
Researchers from UAB are working with the NIH and Bill & Melinda Gates Foundation to study a potential antibiotic to treat maternal and infant sepsis in low-income countries.
New evidence for sex disparity in liver transplants suggests a change may be needed in how livers are allocated.
A mouse model and previous studies suggest that genetic intervention in SHANK3-related ASD may be most effective earlier in development.
UAB’s CCTS joins a nationwide collaboration creating a secure, central database of electronic health records from coronavirus patients.
A grant from the NICHD will help study hepatitis B transmission in African newborns.
Results show that retinitis pigmentosa 59 may not be a congenital disorder of glycosylation, as was long assumed.
Everyone was fast this spring: the businesses that contributed to the fund, the scientists and physicians who crafted research proposals, and the senior School of Medicine researchers who chose which proposals got money.
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