Research - News
Because hypertension and uncontrolled blood pressure are major risk factors for heart disease and stroke, achieving equity in heart and brain health in the United States cannot be reached without paying attention to social determinants of health, a study shows.
These nanowires, which can transport electrons to help a microbe make energy, were first described in a Geobacter bacteria; but now nanowires appear to be widespread in both bacteria and archaea prokaryotes.
This funding will be used to research multiple health conditions, including alcohol-related liver disease, Alzheimer’s disease, breast cancer, heart failure, inflammatory bowel disease and Zhu-Tokita-Takenouchi-Kim syndrome.
UAB researchers conducted a nationwide population-level study to assess the cardiovascular health in Asian American adults. Results revealed that cardiovascular health declined in foreign-born Asian Americans by 28 percent from 2011-2020.
Researchers used a mouse model and cutting-edge neurobiological techniques to show how psychological stress during adolescence alters neuronal functions in the brain, resulting in altered postpartum social behavior.
Findings from an ongoing UAB study suggest obesity is a driving factor in the development of PCOS, the most common endocrine cardiometabolic disorder of women.
Chronic obstructive pulmonary disease patients with type 2 inflammation saw rapid and sustained improvements in their disease after treatment with the monoclonal antibody dupilumab.
The 31 new scholars from 22 U.S. institutions are all outstanding early career faculty in science who have the potential to become leaders in their research fields and advance diversity, equity and inclusion. Each scholar will receive up to $8.6 million over 10 years.
UAB researcher Yusen Zhai, Ph.D., discovered that overall mental health care accessibility took a step forward during the pandemic due to telehealth.
UAB researchers conducted a study including approximately 20,000 left ventricular assist device recipients and found that women had worse clinical outcomes compared with men across social and clinical subgroups of interest.

Results from the Chronic Hypertension and Pregnancy trial found treating preexisting mild chronic hypertension in pregnant women is safe from both the mom and baby. Results published in April 2022 have since led to changes in national guidelines.
The University of Alabama at Birmingham has been awarded $8 million from the United States Department of Energy’s National Nuclear Security Agency.
New study indicates that StreetBit has the potential to save millions of dollars annually and reduce pedestrian injuries by implementing such programs on a larger scale.
UAB was one of four sites leading a clinical trial to evaluate the effectiveness of adding Pembrolizumab to endometrial cancer care.
Knowledge of this previously unrecognized mechanism may aid therapy for patients with interleukin-6 signaling mutations and hyper-IgE Syndrome, or HIES.
Uncovering a pathophysiological mechanism that initiates, transitions and sustains neuropathic pain holds promise for treating neuropathic pain.
Description of this mechanism offers a promising therapeutic target to limit lung injury and death. Lower respiratory tract infections, including bacterial pneumonia, are the fourth-leading cause of death worldwide, with 120 million to 156 million cases and 1.4 million deaths a year.
This study will examine the average treatment effects of M2M-C, a telehealth cardio-focused exercise program, on core indicators of major cardiometabolic risk factors.
Three teams of researchers from UAB are analyzing the intergenerational transmission of obesity.
This is the first example of a chelator-free-radiolabeled polymersome capable of a long-term multiday positron emission tomography, or PET, imaging study in vivo.
The drug appears to help strengthen pathways in the brain, improving the ability of neurons to communicate with each other.
Advanced warning of an elevated risk for seizures could help patients take protective measures to minimize the effects, or possibly even stop the seizure before it begins.
The Alabama Innovation Corporation awarded two UAB startups with grants during the second round of Innovate Alabama Supplemental Grant awards.
Researchers identify a new target to fight infections caused by the opportunistic lung pathogen Streptococcus pneumoniae — interference with the bacteria’s fermentation metabolism.
The study found that using a vaginal swab was more accurate than using urine for three types of sexually transmitted infections.
These effector memory B cells appear poised for a rapid serum antibody response upon secondary challenge one year later, and evidence shows that the cells in this subset differ from all previously described memory B cell subsets.
The trial will evaluate the effects of low doses of psilocybin on combating demoralization in broader populations.
The All of Us Southern Network has enrolled more than 30,000 people. The new Dothan location will extend enrollment opportunities into the Wiregrass.
The grant validates the science of Alveolus Bio, and the funds will support development of first-of-its-kind inhaled biotherapeutics to treat chronic lung diseases.
The federal mandate, which was announced in 2011 and implemented in 2014, limited acetaminophen to 325 milligrams per opioid-acetaminophen combination pill. Acetaminophen is toxic to livers at high doses.
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