Advanced special topics course in metabolomics 2023
(GBSC 724)

Course Description

Course will be held on Mondays, Wednesdays and Fridays 9-10:30 am in the SHELBY 1115

Tentative Schedule

The PowerPoint versions are available on request to

Date Lecturer Topic
Jan 9, Mon S. Barnes Transition from metabolism to metabolomics and targeted/untargeted approaches [PDF File]
Jan 11, Wed S. Barnes The extraordinary chemistry of the metabolome [PDF File]
Jan 13, Fri H. Tiwari Designing a complex metabolomics experiment [PDF File]
Jan 16, Mon No class Martin Luther King Holiday
Jan 18, Wed W. Placzek The platform - fundamentals in NMR and metabolomics [PDF File]
Jan 20, Fri J. Prasain Extracting the metabolome (fluids, cells and tissues) [PDF File]
Jan 23, Mon S. Barnes The platform – fundamentals in GC- and LC-mass spectrometry [PDF File]
Jan 25, Wed D. Sharer Targeted metabolomics for congenital disease in children [PDF File]
Jan 27, Fri J. Prasain MSMS of small molecules - interpretation [PDF File]
Jan 30, Mon J. Prasain SWATH-MS, Ion Mobility and LC-MS for lipidomics [PDF File]
Feb 1, Wed W. Placzek Processing NMR data [PDF File]
Feb 3, Fri   Students’ presentations
Feb 6, Mon S. Barnes MS-DIAL 4.92 – a comprehensive metabolomics tool – bring PC
Feb 8, Wed M. Wang* GNPS analysis of MS-DIAL data [PDF File]
Feb 10, Fri S. Barnes Statistical analysis of MS-DIAL data with MetaboAnalyst 5.0
Feb 13, Mon S. Barnes MZmine 3.0.10 hands-on class exercise
Feb 15, Wed S. Barnes Drivers of the plasma metabolome – paper discussion
Feb 17, Fri   The TMAO story and follow up – Students’ presentations
Feb 20 Mon S. Barnes Pathway databases and metabolomics workbench
Feb 22, Wed S. Barnes Bile acid metabolism
Feb 24, Fri   No Class
Feb 27, Mon C. Beecher*** Isotope Ratio Outlier Analysis (IROA) - video
Mar 1, Wed C. Beecher*** Building a metabolite standards database
Mar 3, Fri   Student presentations
Mar 6, Mon S. Barnes Peaks-to-pathways - Mummichog analysis of data
Mar 8, Wed S. Barnes Isotopes and pathway dynamics
Mar 10, Fri Art Edison**** NMR metabolomics
Mar 13, Mon J. Prasain Lipid maps database [PDF File]
Mar 15, Wed J. Prasain Validating metabolites and novel prostanoid molecules [PDF File]
Mar 17, Fri   Student presentations
Mar 20, Mon S. Barnes Real-time connection of Metabolomics with Medicine and Surgery and the rest of life [Gordon Research Conference] [PDF File]
Mar 22, Wed J. Kabarowski Lipid imaging-mass spectrometry (video)
Mar 24, Fri S. Barnes Metabolomics in clinical studies
Mar 27, Mon X. Hu***** Integration of -omics data [PDF File]
Mar 29, Wed T. Marquez-Lago Machine learning and artificial intelligence and its application to metabolomics
Mar 31, Fri Laura Reed (UA) Integrating the metabolome with the genome and transcriptome in the context of environmental exposure in the fruit fly (video)
Apr 3, Mon S. Barnes Metabolomics and microbiome
Apr 5, Wed J. Zhang Measurement of mitochondrial function using the Seahorse extracellular flux bioanalyzer
Apr 6, Thur R. Quinn** Novel bile acid-microbiome interactions [PDF File]
Apr 7, Fri S. Barnes Course review
Apr 14, Mon   FINAL exam due

**Michigan State U.
***IROA Technologies
****U. Georgia
*****Emory U.