Advanced special topics course in metabolomics 2024
(GBSC 724)

Course Description

Course will be held on Mondays, Wednesdays and Fridays 9-10:30 am in the SHELBY 1115

Tentative Schedule

The PowerPoint versions are available on request to sbarnes@uab.edu.

Date Lecturer Topic
Jan 8, Mon S. Barnes Transition from metabolism to metabolomics and targeted/untargeted approaches [PDF File]
Jan 10, Wed S. Barnes The extraordinary chemistry of the metabolome [PDF File]
Jan 12, Fri H. Tiwari Designing a complex metabolomics experiment [PDF File]
Jan 15, Mon No class Martin Luther King Holiday
Jan 17, Wed W. Placzek The platform - fundamentals in NMR and metabolomics [PDF File]
Jan 19, Fri J. Prasain Extracting the metabolome (fluids, cells and tissues) [PDF File]
Jan 22, Mon S. Barnes The platform – fundamentals in GC- and LC-mass spectrometry [PDF File]
Jan 24, Wed D. Sharer Targeted metabolomics for congenital disease in children [PDF File]
Jan 26, Fri J. Prasain MSMS of small molecules - interpretation [PDF File]
Jan 29, Mon J. Prasain SWATH-MS, Ion Mobility and LC-MS for lipidomics [PDF File]
Jan 31, Wed W. Placzek Processing NMR data [PDF File]
Feb 2, Fri   Students’ presentations
Feb 5, Mon S. Barnes MS-DIAL 4.92 – a comprehensive metabolomics tool – bring PC
Feb 7, Wed M. Wang* GNPS analysis of MS-DIAL data
Feb 9, Fri S. Barnes Statistical analysis of MS-DIAL data with MetaboAnalyst 5.0
Feb 12, Mon S. Barnes MZmine 3.9 hands-on class exercise
Feb 14, Wed S. Barnes Pathway databases and metabolomics workbench
Feb 16, Fri J. Mitchell** Asari – accelerating metabolomics data analysis [PDF File]
Feb 19 Mon   The TMAO story and follow up – Students’ presentations
Feb 21, Wed S. Barnes Bile acid metabolism
Feb 23, Fri Andrew Patterson*** Novel bile acid-microbiome interactions
Feb 26, Mon S. Barnes Peaks-to-pathways - Mummichog analysis of data
Feb 28, Wed C. Beecher**** Isotope Ratio Outlier Analysis (IROA) - video
Mar 1, Fri C. Beecher**** Building a metabolite standards database
Mar 4, Mon   Student presentations
Mar 6, Wed S. Barnes Isotopes and pathway dynamics
Mar 8, Fri Art Edison***** NMR metabolomics
Mar 11, Mon J. Prasain Lipid maps database
Mar 13, Wed J. Prasain Validating metabolites and novel prostanoid molecules
Mar 15, Fri   Student presentations
Mar 18, Mon S. Barnes In situ lipidomics in the surgical suite
Mar 20, Wed J. Kabarowski Lipid imaging-mass spectrometry (video)
Mar 22, Fri S. Barnes Metabolomics in clinical studies
Mar 25, Mon Laura Reed (UA) Integrating the metabolome with the genome and transcriptome in the context of environmental exposure in the fruit fly (video)
Mar 27, Wed X. Hu****** Integration of -omics data
Mar 29, Fri T. Marquez-Lago Machine learning and artificial intelligence and its application to metabolomics
Apr 1, Mon S. Barnes Metabolomics and microbiome
Apr 3, Wed TBA TBA
Apr 5, Fri S. Barnes Course review
Apr 12, Mon   FINAL exam due

*UC-Irvine
**Jackson Labs
***Penn State U.
****IROA Technologies
*****U. Georgia
******Emory U.