CFAR Biostatistics and Analysis Core

Research Administration Centers and Cores CFAR Biostatistics and Analysis Core

CFAR Biostatistics and Analysis Core

Directory Category: Core

The purpose of Biostatistics and Analysis Core is primarily to provide statistical, epidemiologic, health services research and bioinformatics support to CFAR investigators for the development of research proposals including data management and quality control with analyses. This is accomplished by a collaborative team of investigators who provide input on study design and analyses as well as logistical issues and problems impacting the quality and integrity of studies in addition to advice on literature interpretation, assessment of new methodologies and support for studying unique aspects of HIV in the US Deep South. The range of studies include pilot data and phase I clinical trials for drug discovery to pathogenesis, prevention (both primary and secondary) and the "new" natural history of HIV infection in the treatment era. The type of studies include both genetic and non-genetic such as observational designs, clinical research, health services research, health economic modeling and other evaluations such as mixed treatment comparisons, indirect treatment comparisons and causal modeling.

EXPERTISE

  • Clinical trials (Phase I, II, III) design and conduct
  • Clinical research
  • Observational studies (cohort, case-control, and other)
  • Genetic studies (GWAS, Microarray, etc.)
  • Secondary data analysis
  • Longitudinal data analysis including mixed models
  • Survival analysis
  • Categorical data analysis including logistic regression
  • Missing data imputation techniques
  • Propensity score analysis and related methods
  • Development of study questionnaires (data collection tools) and electronic data entry system
  • Cost-effective analysis
  • Simulation modeling
  • Decision analysis
Affiliated UWIRCs