Plasminogen activator inhibitor-1 is a serine protease inhibitor involved in inhibition of fibrinolysis. My laboratory is interested in the regulatory role of PAI-1 in lung fibrogenesis. To this end, we are examining the molecular events related to fibrin deposition, PAI-1 regulation and fibroblast biology both in in vitro and animal models, and are testing novel gene delivery systems for therapeutic purposes.
1993-Present. Assistant Professor of Medicine, University of Alabama at Birmingham, Birmingham, AL
1993. The Scripps Research Institute, La Jolla, CA, Vascular Biology Research Fellow
1987-90. Univ. CA San Diego Med. Cen., San Diego, CA, Pulmonary Disease Fellow
1986-87. Univ. Chicago Med. Cen., Chicago, IL, Physiology Research Fellow
1983-86. Univ. Chicago Med. Cen., Chicago, IL, Medicine
1983. NY University School of Medicine, M.D., Medicine
1980. Columbia University, NY, NY, M.A., Anatomy
1978. State University of New York, Oneonta, NY, B.S., Chemistry