Mitchell A. Olman, M.A., M.D.-Role of Fibrinolysis in Lung Matrix Remodeling


Research Description:

Plasminogen activator inhibitor-1 is a serine protease inhibitor involved in inhibition of fibrinolysis. My laboratory is interested in the regulatory role of PAI-1 in lung fibrogenesis. To this end, we are examining the molecular events related to fibrin deposition, PAI-1 regulation and fibroblast biology both in in vitro and animal models, and are testing novel gene delivery systems for therapeutic purposes.


Biography:

1993-Present. Assistant Professor of Medicine, University of Alabama at Birmingham, Birmingham, AL

1993. The Scripps Research Institute, La Jolla, CA, Vascular Biology Research Fellow

1987-90. Univ. CA San Diego Med. Cen., San Diego, CA, Pulmonary Disease Fellow

1986-87. Univ. Chicago Med. Cen., Chicago, IL, Physiology Research Fellow

1983-86. Univ. Chicago Med. Cen., Chicago, IL, Medicine

1983. NY University School of Medicine, M.D., Medicine

1980. Columbia University, NY, NY, M.A., Anatomy

1978. State University of New York, Oneonta, NY, B.S., Chemistry


Recent Publications:


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