Charles W. Prince, Ph.D.--Osteopontin and other
Matrix Components in Normal and Pathological StatesCharles W. Prince, Ph.D.--Osteopontin and other
Matrix Components in Normal and Pathological StatesOur laboratory examines the biochemistry and functions of extracellular matrix components, particularly osteopontin, in normal and pathological states. We are also interested in the regulation of gene expression by vitamin D and its analogs in biological mineralization and in molecular events during tumor promotion and metastasis. A recent focus has been on alterations of matrix protein structure due to post-translational modifications by homocyteine.
Professor, Departments of Nutrition Sciences, Biomedical Engineering, Oral Biology, and Biochemistry & Molecular Genetics
Senior Scientist: Cell Adhesion and Matrix Research Center, Center for Aging, Comprehensive Cancer Center, Arthritis and Musculoskeletal Disease Center, Center for Metabolic Bone Disease, Biomedical Implant Center, Clinical Nutrition Research Center
