CAMRC Home PageMy research group is exploring how hormonal and nutritional factors modulate the ability of tumor cells to invade and metastasize. To that end, we have developed a basement-membrane-like human extracellular matrix as an in vitro model system for studying tumor migration through living human tissues. Recent work has focused on the relationship between the adhesion molecule CD44, growth factors, and the invasive phenotype. Further, we have participated in studies of a variety of distinct strategies including mutation compensation to treat solid human neoplasms.
Rank - Professor of Pathology, Cell Biology and Surgery and Director, Division of Anatomic Pathology
Honors - Fellow, Royal Society of Medicine, 1992; Phi Beta Delta, Honor Society for International Scholars, 1993; International Skeletal Society, 1994. Alpha Omega Alpha, 1996.
Training background - Intern, Resident in Pathology, Mayo Graduate School, 1975-1979; Research Associate, Lab of Pathophysiol., NCI, NIH, 1979-1981; Fellow in Surg. Pathol., Univ. of Minnesota, 1981-1982; Instructor in Pathology, Mayo Medical School, 1976-1979; Assistant Professor, Univ. of North Carolina, 1982-1988; Associate Professor, Univ. of North Carolina, 1988-1990; Professor, UAB, 1990-Present.