COURSE DESCRIPTIONS FOR MASTERS DEGREE IN CLINICAL LABORATORY SCIENCES


In addition to the courses listed below, courses in other programs may be available.

CLS 600. Quality Management in Clinical Laboratory Markets--TQM/CQI principles, practices, and techniques for outcomes of individuals, groups and organization-wide performance; focus on quality management elements, linking relationships, customer satisfaction. 3 hours.

CLS 601. Designing Effective Laboratory Medicine Services--Point-of-care-testing, network, regional clusters and new forms of laboratory services delivery; automation and robotics optimization; integration of theory and research for laboratorians regarding organizational performance, change, leadership effectiveness, and laboratorian attachment for the organization. 3 hours.

CLS 602. Managing Clinical Laboratory Financial and Cost Accounting Operations--Laboratory cost accounting, project management, product cost analysis, reimbursement mechanisms, fee determination, budgeting, performance indicators, lease vs. buy; relationships with quality management, legislation, external stakeholders, utilization management. 3 hours.

CLS 603. Strategic Human Performance Technology for Laboratory Medicine Professionals--Human performance technology principles; evaluation of systemic processes to influence human behavior and performance outcomes, process management techniques. 3 hours.

CLS 605. Transfusion Service Management--Regulatory and compliance issues; inspection and accreditation; Good Manufacturing Practices (GMP); historical perspective; impact of health care reform on organization and delivery of services; legal and employment issues; personnel interview, selection, discipline, competency assessment; ethical issues; quality assessment and improvement; blood bank information systems; budget, financial management, and cost analysis. 3 hours.

CLS 610. Advanced Technology Assessment--Critical literature review, instrument/method evaluation techniques, and outcomes assessment models; application of critical thinking skills to evaluate methodological and substantive validity of laboratory medicine practices. 3 hours.

CLS 611. Research Methods--Application of research design to a clinical problem or project. 1-4 hours.

CLS 620. Applications of Educational Methodology--Curriculum and course development and implementation, objectives, application of learning theory to educational strategies laboratory teaching techniques; observation and supervised practice teaching, measurement and evaluation, presentation techniques. 1-3 hours.

CLS 625. Principles of Blood Cell and Bone Marrow Counting--Bone marrow aspirate and biopsy preparation and visual examination; review of normal and disease morphology; determination of bone marrow cellularity and myeloid:erythroid ratio. 2 hours.

CLS 630. Advanced Hemostasis--In-depth discussion of the plasma coagulation system and cellular systems comprising hemostasis. Pathophysiology and hemostasis laboratory diagnosis and case management of congenital and acquired thrombotic and hemorrhagic disorders. Quality and efficacy issues affecting hemostasis laboratory testing. 2 hours.

CLS 631. Advanced Hematology--Structure and function of bone marrow, spleen and lymphatic system; stem cell differentiation, hematopoiesis, erythrocyte kinetics. Laboratory diagnosis and case management of acute and chronic leukemia, myeloproliferative disorders, myelodysplastic syndromes, anemias. application of cell population scattergrams and phenotyping. Quality and efficacy issues affecting hematology laboratory testing. 2 hours.

CLS 637. Molecular Techniques--Molecular diagnostic methodologies, basic concepts and clinical applications; issues of social, ethical and economic concern for laboratory medicine markets. 3 hours.

CLS 638. Flow Cytometry--Principles of flow cytometry: instrumentation, specimen processing, methodology of testing and analysis; standards, safety, quality assurance, and controls; current and future clinical applications. 2 hours.

CLS 642. Infectious Disease Principles--Clinical relevance of microbes; identification of microbial agents; antimicrobial studies; case analysis; clinical laboratory operations. 3 hours.

CLS 643. Microbial Epidemiology Principles--Special host infections, notifiable diseases laws, surveillance methods, nosocomial infections, population-based infection control practices. 3 hours.

CLS 650. Immunology--Antigens, antibodies, cytokines; cellular and humoral immune response; genetics of immune system; complement; phagocytosis; adhesion molecules; major histocompatibility complex; antigen presentation and T and B cell activation; mucosal immunology; transplantation. 1 hour.

CLS 654. Tissue Immunopathology--Principles and practical applications. 3 hours.

CLS 663. Blood Transfusion Therapy--Physiology of hematopoiesis; etiology, pathophysiology, laboratory diagnosis and advanced testing protocols for hemolytic anemias, myeloproliferative disorders, myelodysplastic syndromes, and acute leukemias; red cell metabolism, survival and preservation; physiology of blood loss and transfusion replacement; use of blood substitutes; immunomodulation by transfusion; immune mechanism of red cell destruction; adverse effects of transfusion; transfusion-transmitted infections, hemolytic disease of the newborn. 3 hours.

CLS 664. Advanced Immunohematology--Red cell blood group systems: antigens and antibodies, phenotypes, molecular biology, immunogenetics, biochemistry, serology and clinical significance; HLA system; parentage testing; red cell auto antibodies; drug induced red cell sensitization; polyagglutination; leukocyte and platelet antigens, investigation of positive DAT; advanced techniques for problem solving; case studies. 3 hours.

CLS 671. Clinical Laboratory Toxicology--Chain of custody, specimen integrity, screening, confirmation, courtroom procedures; metals, street drugs, alcohols, volatiles, hydrocarbons, insecticides, psychotic drugs, gases and other poisons. 2 hours.

CLS 675. Advanced Clinical Chemistry--Nutrition and wellness, reproductive and pregnancy monitoring; preparation for accreditation; consultation; nanotechnology reference intervals and biological variation. 3 hours.

CLS 684. Clinical Practicum--Directed clinical practice; laboratory procedures and methods; quality control systems, preventive maintenance, problem solving, safety. 1-6 hours.

CLS 686. Special Topics in Clinical Laboratory Sciences--Selected advanced topics of current scientific, clinical, and professional importance. 1-4 hours.

CLS 688. Managing and Marketing Laboratory Medicine Services--Services, consultation, managerial skills for relationship marketing and service management principles, development of marketing plans; determining customer service gaps. 3 hours.

CLS 691. Seminar in Clinical Laboratory Sciences--Current clinical, professional, and research developments in clinical laboratory science. Presentations by participants. Repeated registration; attendance required for all graduate students. 1 hour.

CLS 692. Immunohematology Seminar--Current clinical, administrative, professional, and research developments in immunohematology and transfusion medicine. 1 hour.

CLS 693. Scientific Publications Analysis--Review and scientific critique of current literature. 1 hour.

CLS 698. Master's Level Non-Thesis Research. 1-6 hours.

CLS 699. Master's Level Thesis Research--Implementation of research. 1-6 hours.

Faculty

Typical Program

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