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Proteomics and Mass Spectrometry (BMG/PHR 744)

Course Masters: Drs Barnes and Renfrow

Students participating in this course become familiar with standard analysis of proteins and protein mixtures by analytical mass spectrometry. This includes the analysis of recombinant and native isolations of proteins including the analysis of post translational modifications.  The first month of the course will focus on the fundamentals of mass spectrometry and protein analysis and will be open to first year students.  The second and third months of the course is followed by an applications section for students who have completed their first year course requirements. Included topics throughout the course include, sample preparation, mass spectrometry instrumentation, mass spectral interpretation, proteomic experimentation, database searching, analysis of protein modifications, targeted analysis of proteins in complex mixtures, and structural techniques in mass spectrometry.