Structural Biology Faculty

Our structural biology faculty members are a diverse group, housed in many departments. The common theme of the structural biology faculty members is recognition of the central importance of the gaining and utilizing structural information to understand biological function at the molecular level.

The systems under study include proteins involved in the immune response, ion and metabolite transport, cell-cell recognition, multidrug resistance, virus-host interactions and signal transduction protein folding, protein-nucleic acid interactions and more.

In addition, a number of our faculty utilize structural data to design novel drugs for a variety of infectious and chronic diseases including influenza and HIV, bacterial host interactions, methicillin-resistant Staphylococcus aureus (MRSA), anthrax, tularemia and other pathogenic bacteria, oral bacteria that cause gum and tooth diseases, cystic fibrosis, Parkinson’s and Alzheimer’s diseases, atherosclerosis, diabetes and several different cancers (i.e. prostate, colon, breast and lung cancer).

Please Explore, Discover, and Enjoy!

 Aller
Stephen G. Aller, Ph.D.
Assistant Professor, Department of Pharmacology & Toxicology

Areas of focus: Structure/function of Membrane Proteins, Crystallography Scaffolds, Structure-Based Drug Design, Nanoprobes

Publications

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Ananth
G.M. Anantharamaiah, Ph.D.
Professor , Department of Medicine
Division of Gerontology/Geriatrics/Palliative Care


Areas of focus: Structure and Function Of Plasma Apolipoproteins, Apo-A1 Structure and Function, Apo-E Structure and Function, Structure Of Apo-A-1 In Alzheimer Disease Research

Publications 

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 Barnes
Steve Barnes, Ph.D.
Professor, Pharmacology and Toxicology

Areas of focus: Mass Spectrometry, Crystallins, Bile Acid Acyltransferase

Publications

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Brouillette Christie G. Broullette, Ph.D.
Research Professor, Department of Chemistry
Associate Director of Molecular Biophysics , Center for Biophysical Sciences and Engineering

Areas of focus:  Protein Structural Cooperativity and Energetics, Biophysics, Antibacterial Drug Discovery

Publications

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Brouillette
Wayne Brouillette, Ph.D.
Professor, Department of Chemistry

Areas of focus: Drug Design and Medicinal Chemistry, Biodefense, Molecular Modeling

Publications

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 chattopadhyay
Debasish Chattopadhyay, Ph.D.
Professor, School of Medicine

Areas of focus: Protein Structure Based Drug Discovery, Host Pathogen Interaction, Vaccine Design

Publications

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 Champion
Champion Deivayanagam, Ph.D.
Research Assistant Professor, Department of Vision Sciences

Areas of focus: X-Ray Crystallography, Dental Caries, Bacterial Surface Proteins, Enzymes


Publications


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DeLucas
Lawrence J. DeLucas, O.D., Ph.D.

Professor, Department of Optometry

Areas of focus: Membrane Protein Structure-Function Relationships, Cystic Fibrosis Transmembrane Regulator, X-Ray Crystallography

Publications

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Dokland
Terje Dokland, Ph.D.

Associate Professor, Department of Microbioogy


Areas of focus: Virus Assembly, Cryo-Electron Microscopy

 

Publications

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 Erlandsens2-1
Heidi Erlandsen, Ph.D.

Instructor, Department of Periodontology

Areas of focus:
Protein Crystallography, Molecular Mechanisms of Cell Signaling, Metabolic Disease

Publications


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 Graves2
David Graves, Ph.D.
Professor and Chair, Department of Chemistry

Areas of focus: Protein/Nucleic Acid Interactions, Intercalating Agents, NMR, Biophysics

Publications

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 Green
Todd Green, Ph.D.
Assistant Professor, Department of Microbiology

Areas of focus: Viral Transcription and Replication, Capsid Structure

Publications

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 Eugenia_Kharlampieva
Eugenia Kharlampieva, Ph.D.
Assistant Professor, Department of Chemistry

Areas of focus:
Synthesis and Assembly of Bio-Mimetic Polymers, Multifunctional Biohybrid Nanocomposites, Vibrational Spectroscopy, Neutron Scattering

Publications


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Kim
Helen Kim, Ph.D.
Associate Professor, Department of Pharmacology and Toxicology

Areas of focus: Proteomics of Dementia, Protein Oxidation, Mass Spectrometry

Publications

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Krishna
N. Rama Krishna, Ph.D.

Professor, Department of Biochemistry and Molecular Genetics

Areas of Focus: Biomolecular NMR spectroscopy, protein structural biology, and drug design

Publications

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 Lucius2
Aaron Lucius, Ph.D.
Associate Professor, Department of Chemistry

Area of focus: Protein Machines, Motor Proteins, Chaperone/Protease Systems, Biophysics

Publications

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 Luo

Ming Luo, Ph.D.
Professor, Associate Director, Center for Biophysical Sciences and Engineering

Areas of focus: Virus Structure, Antiviral Drugs, X-Ray Crystallography

Publications

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 Mobley
James A. Mobley, Ph.D.
Director, UAB MSP Facility, Assistant Professor, Department of Surgery

Publications

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 Muccio


Donald Muccio, Ph.D.
Professor, Department of Chemistry

Areas of focus: Molecular Biophysics, Drug-Protein Interactions, Conformationally Constrained Retinoids

Publications

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Patterson

James C. Patterson, Ph.D.
Assistant Professor, Department of Chemistry

Areas of focus: Computational Inorganic Chemistry, Computational Biophysics

Publications

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Prevelige

Peter E. Prevelige, Ph.D.
Professor, Department of Microbiology

Areas of focus: Virus Assembly, Bio-Inspired Nanoparticles, Mass Spectrometry

Publications

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Saad

Jamil S. Saad, Ph.D.

Assistant Professor, Department of Microbiology

Areas of focus: HIV-Host Interactions, NMR, Protein-Protein and Protein-Lipid Interactions 

Publications

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Segrest

Jere Segrest, M.D., Ph.D.
Professor, Department of Medicine

Publications

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Sha

Bingdong Sha, Ph.D.
Professor, Department of Cell Biology

Areas of focus: Molecular Chaperones, Unfolded Protein Response, Mitochondrial Translocons

Publications

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Song2
Yuhua Song, Ph.D.
Assistant Professor, Biomedical Engineering

Areas of focus: Computational Biology, Cancer Biology, Cell Adhesion and Focal Adhesion Disassembly

Publications

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cNarayana
Narayana Sthanam, Ph.D.

Professor, Department of Optometry

Areas of focus: Microbial Pathogenicity, Macromolecular Structure/Function, X-ray Crystallography

Publications

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Vassylyev_Dmitry
Dmitri Vassylyev, Ph.D.
Professor, Department of Biochemistry and Molecular Genetics

Publications

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Velu

Sadanandan Velu, Ph.D.
Associate Professor, Department of Chemistry

Areas of focus: Structure Based Drug Design, Anti-Cancer Agents, Anti-Infective Agents

Publications


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Wang
Pengfei Wang, Ph.D.

Associate Professor, Department of Chemistry

Areas of focus: Photochemistry, Carbohydrate Chemistry, Organic Synthesis, Photo Responsive Materials

Publications

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