Our structural biology faculty members are a diverse group, housed in many departments. The common theme of the structural biology faculty members is recognition of the central importance of the gaining and utilizing structural information to understand biological function at the molecular level.
The systems under study include proteins involved in the immune response, ion and metabolite transport, cell-cell recognition, multidrug resistance, virus-host interactions and signal transduction protein folding, protein-nucleic acid interactions and more.
In addition, a number of our faculty utilize structural data to design novel drugs for a variety of infectious and chronic diseases including influenza and HIV, bacterial host interactions, methicillin-resistant Staphylococcus aureus (MRSA), anthrax, tularemia and other pathogenic bacteria, oral bacteria that cause gum and tooth diseases, cystic fibrosis, Parkinson’s and Alzheimer’s diseases, atherosclerosis, diabetes and several different cancers (i.e. prostate, colon, breast and lung cancer).
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