Faculty & Research

Faculty in the CMDB theme are affiliated with multiple departments across UAB. The scientific interests of the faculty are very diverse and interdisciplinary in nature and encompass cell, molecular, and developmental biology using modern tools and approaches as well as a wide range of model organisms and cell culture systems. The research conducted by CMDB faculty addresses fundamental cellular and molecular questions that provide the basis for understanding and treating human disease and developmental abnormalities. Specific research activities of the CMDB faculty can be viewed by visiting individual faculty research and profile pages or by looking under the faculty research focus areas. CMDB faculty research is supported by awards from various agencies, with the majority coming from the National Institutes of Health.

Click on the research focus area in the menu bar on the left to see a listing of faculty members by research focus area.

Anupam Agarwal, M.D. - Medicine
Regulation of heme oxygenase gene expression in kidney and vascular injury
Disease Mechanisms    Fundamental Cellular Mechanisms

Jonas Almeida, Ph.D. - Pathology

Informatics; personalized medicine; systems biology; mathematical modeling
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms

Namasivayam Ambalavanan, M.D. - Pediatrics
Neonatal lung development; mechanisms underlying neonatal pulmonary vascular remodeling and neonatal pulmonary hypertension

G. M. Anantharamaiah, Ph.D. - Medicine
Apolipoproteins; amphipathic helices; atherosclerosis
Disease Mechanisms    Fundamental Cellular Mechanisms

Daniel Balkovetz, M.D., Ph.D. - Medicine
Epithelial cell biology; epithelial cell signal regulation; regulation of paracellular transport across epithelial cell
Disease Mechanisms    Fundamental Cellular Mechanisms

Scott Ballinger, Ph.D. - Molecular and Cellular Pathology
Environmental cardiology; free radical biology; mitochondrial function
Disease Mechanisms    Fundamental Cellular Mechanisms

Marcas Bamman, Ph.D. - Cell, Developmental and Integrative Biology
Cell/matrix interactions in disease and tissue regeneration

Malay Basu, Ph.D. - Pathology
Genomics, bioinformatics, high-erformance computing, grid computing, computational biology, evolution

Zsuzsanna Bebok, M.D.
 - Cell, Developmental and Integrative Biology
Membrane protein biogenesis in epithelial cells (CFTR as model); unfolded protein response
Disease Mechanisms    Fundamental Cellular Mechanisms

David Bedwell, Ph.D. - Microbiology
Mechanism of translation termination; therapies to suppress stop mutations
Disease Mechanisms    Fundamental Cellular Mechanisms

Susan Bellis, Ph.D. - Cell, Developmental and Integrative Biology
The role of integrin receptors in human biology and disease

Etty Benveniste, Ph.D. - Cell, Developmental and Integrative Biology
Immune/nervous system interactions

Bakhrom Berdiev, M.D., Ph.D. - Cell, Developmental and Integrative Biology
The CFTR chloride channel control of epithelial sodium channel under physiological and pathological conditions
Disease Mechanisms    Fundamental Cellular Mechanisms

Mark Bevensee, Ph.D. - Cell, Developmental and Integrative Biology
Cellular and molecular physiology of acid-base transporters and pH regulation
Disease Mechanisms    Fundamental Cellular Mechanisms

Mary-Ann Bjornsti, Ph.D. - Pharmacology & Toxicology

Karl-Heinz Braunewell, Ph.D. - Biochemistry & Molecular Genetics, SRI
Molecular and cellular neurobiology; function of neuronal calcium sensors in health and disease
Disease Mechanisms    Fundamental Cellular Mechanisms

Michael Brenner, Ph.D. - Neurobiology
Molecular studies of astrocytes in health and disease
Disease Mechanisms    Fundamental Cellular Mechanisms

Peter Burrows, Ph.D. - Microbiology
Lymphocyte development and function
Disease Mechanisms    Fundamental Cellular Mechanisms

Steven Carroll, M.D., Ph.D. - Pathology
The Role of Neuregulin-1 in Peripheral Nervous System Neoplasia

Kevin Cassady, M.D. - Medicine, Infectious Disease
Pediatric infectious diseases

Chenbei Chang, Ph.D. - Cell, Developmental and Integrative Biology
Signaling transduction in development and diseases
Birth Defects & Development     Fundamental Cellular Mechanisms

Ching-Yi Chen, Ph.D. - Biochemistry & Molecular Genetics
Mechanism and regulation of mammalian mRNA turnover
Fundamental Cellular Mechanisms

Yabing Chen, Ph.D. - Pathology
Gene regulation in the pathogenesis of cardiovascular diseases, osteoporosis, and cancer

Igor Chesnokov, Ph.D. - Biochemistry & Molecular Genetics
DNA replication and cell cycle in eukaryotes
Fundamental Cellular Mechanisms

Louise Chow, Ph.D. - Biochemistry & Molecular Genetics
Human papillomavirus DNA replication and pathogenesis
Disease Mechanisms    Fundamental Cellular Mechanisms

Sarah Clinton, Ph.D. - Psychiatry & Behavioral Neurobiology
Neurodevelopmental and environmental factors that underlie susceptibility to anxiety and depression
Birth Defects & Development     Disease Mechanisms

James Collawn, Ph.D. - Cell, Developmental and Integrative Biology
Cystic fibrosis; endocytosis; protein trafficking
Disease Mechanisms    Fundamental Cellular Mechanisms

Rita Cowell, Ph.D. - Psychiatry & Behavioral Neurobiology
Transcriptional regulation of early postnatal brain development: Insights into the pathology of autism and schizophrenia
Birth Defects & Development     Disease Mechanisms    Fundamental Cellular Mechanisms

Judy Creighton, Ph.D. - Anesthesiology
AMPK activates calcium signaling necessary for endothelial barrier repair

Lawrence DeLucas, O.D., Ph.D. - Optometry
Protein crystallography/protein crystal growth
Fundamental Cellular Mechanisms

Patrizia De Sarno, Ph.D. - Psychiatry & Behavioral Neurobiology
Jessy Deshane, Ph.D. - Medicine
Inflammatory diseases of the airway
Disease Mechanisms

Tara DeSilva, Ph.D. - Medicine - Physical Medicine & Rehabilitation
Glutamatergic signaling in demyelination and remyelination in multiple sclerosis

Qiang Ding, Ph.D. - Medicine
Molecular mechanisms of organ fibrosis
Disease Mechanisms

Lynn Dobrunz, Ph.D. - Neurobiology
Synaptic transmission and plasticity in hippocampus

Alan Eberhardt, Ph.D. - Biomedical Engineering
Orthopedic and injury biomechanics, using both experimental and computational approaches
Disease Mechanisms

Michelle Fanucchi, Ph.D. - Environmental Health Sciences
Pulmonary cell biology and toxicology; cell-to-cell interactions in the developing lung as well as in repair after lung injury and disease in children; the role of biochemical defense mechanisms native to pulmonary cells; childhood lung disease and its etiology; drug metabolism
Disease Mechanisms

Stuart J. Frank, M.D. - Medicine
Growth hormone action and GH receptor structure and function
Disease Mechanisms    Fundamental Cellular Mechanisms

Andra R. Frost, M.D. - Pathology
Fibroblast-epithelial cell interactions and developmental pathways in breast cancer
Disease Mechanisms

Kohtaro Fujihashi, D.D.S, Ph.D. - Pediatric Dentistry
The cellular and molecular mechanisms for mucosal immunity in the elderly; molecular and cellular mechanisms for the induction and regulation of mucosally induced tolerance; a mucosal internet of gd, ab T cells, and epithelial cells for mucosal immunity; mucosal immunity in murine models of IBD

Amit Gaggar, M.D., Ph.D. - Medicine, Pulmanory/Allergy/Critical Care
Proteases in Cystic Fibrotic Lung Disease, Proteases in Lung Transplantation

Karen L. Gamble, Ph.D. - Neurobiology
Mechanisms and Entrainment of Circadian Clocks

W. Timothy Garvey, M.D. - Nutrition Sciences
Molecular, metabolic, and genetic basis of type 2 diabetes mellitus, insulin resistance, and obesity

Shawn R. Gilbert, M.D. - Cell, Developmental and Integrative Biology
Clinical and animal studies examining musculosketal health (outcomes measures), inujuries and mechanisms that predispose to injury or impair recovery. Limb and spine deformity, fractures, skeletal maturation, and musculoskeletal infections, and clinical trial comparing bracing styles for clubfeet.

G. Yancey Gillespie, Ph.D. - Surgery
Molecular and viral therapy of malignant primary brain tumors
Disease Mechanisms    Fundamental Cellular Mechanisms

Paul Goepfort, M.D. - Infectious Diseases
Determining the mechanisms allowing T cells to control HIV replication in vivo

Marina Gorbatyuk, Ph.D. - Vision Sciences
Mechanisms of Retinal Degeneration and Search for Neuroprotective Strategies

Daniel Gorelick, Ph.D. - Pharmacology and Toxicology
Steroid and endocrine disruptor signaling during development

Maurizio Grimaldi, Ph.D. - Pharmacology &Toxicology

Alecia K. Gross, Ph.D. - Vision Sciences
Rhodopsin trafficking in rod cells and rhodopsin-mediated retinal degenerations
Birth Defects & Development    Disease Mechanisms 

John Hablitz, Ph.D. - Neurobiology
Cellular mechanisms of neurotransmission
Disease Mechanisms    Fundamental Cellular Mechanisms

John L. Hartman, IV, M.D. - Genetics
Quantitative analysis of genotype-phenotype interaction networks in yeast models of human disease
Fundamental Cellular Mechanisms

Mohammad Hassan, Ph.D. -

Anita Hjelmeland, Ph.D. - Cell, Developmental, and Integrative Biology
Brain tumor, tumor microenvironment, tumor initiating cell, cancer stem cell

Hui-Chen Hsu, Ph.D. - Clinical Immunology, Rheumatology
The BXD2 autoimmune mouse model of lupus and erosive arthritis
Disease Mechanisms    Fundamental Cellular Mechanisms

Kejin Hu, Ph.D. - Biochemistry and Molecular Genetics
Somatic cell nuclear reprogramming, genetic modification of human pluripotent stem cells (PSC), pluripotency and self-renewal of pluripotent stem cells, and differentiation of PSC into blood lineage

Douglas Hurst, Ph.D. - Pathology
Molecular mechanisms of cancer metastasis

Amjad Javed, Ph.D. - Oral and Maxillofacial Surgery
Genetic and molecular signaling for cellular differentiation and skeletogenesis
Birth Defects & Development     Disease Mechanisms    Fundamental Cellular Mechanisms

Peter Jezewski, D.D.S., Ph.D. - Periodontology
Inherited component of craniofacial disorders, syndromic clefting disorders, periodontitis, zebrafish model

Kai Jiao, M.D., Ph.D. - Genetics
TGF-beta/Bmp signaling during cardiogenesis
Birth Defects & Development    Disease Mechanisms

Rajesh K. Kana, Ph.D. - Psychology
The neural substrates of social cognition and the impact of social cognition on language, communication, and other cognitive functions

Natalia Y. Kedishivili, Ph.D. - Biochemistry and Molecular Genetics
Regulation of retinoic acid homeostasis
Birth Defects & Development    Fundamental Cellular Mechanisms

Ilan Kerman, M.D.- Psychiatry
Physical symptoms of depression

Bob Kesterson, Ph.D. - Genetics

Hypothalamic control of feeding behavior
Disease Mechanisms

Kent Keyser, Ph.D. - Vision Sciences
Acetylcholine and Ach receptors

Jeonga Kim, Ph.D. - Medicine
Cross-talk between inflammation and insulin signaling
Disease Mechanisms    Fundamental Cellular Mechanisms

Gwendalyn King, Ph.D. - Neurobiology
Understanding the difference between pathological and non-pathological brain aging
Disease Mechanisms    Fundamental Cellular Mechanisms

Dennis Kucik, M.D., Ph.D. - Pathology
Radiation-induced atherosclerosis and regulation of leukocyte adhesion

Adrienne Lahti, M.D. - Psychiatry & Behavioral Neurobiology
Use of multimodal brain imaging techniques to study the neuropathology of schizophrenia and bipolar disorder and to evaluate the effects of psychotopropic drugs on brain function and biochemistry; translational work aiming at bridging human brain imaging and postmortem studies
Disease Mechanisms    Fundamental Cellular Mechanisms

Jack Lancaster, Ph.D. - Anesthesiology
The biophysics and biochemistry of nitric oxide
Fundamental Cellular Mechanisms

Elliot Lefkowitz, Ph.D. - Microbiology
Viral and microbial genomics and evolution
Fundamental Cellular Mechanisms

Yi-Ping Li, Ph.D. - Molecular and Cellular Pathology
Understanding the mechanisms of bone formation, bone resorption, skeletal development, craniofacial development and cancer bone metastasis; developing effective new therapies for treating and preventing the related diseases
Disease Mechanisms

Yonghe Li, Ph.D. - Medicine
Wnt signaling in cancer
Disease Mechanisms    Fundamental Cellular Mechanisms

Farah Lubin, Ph.D. - Neurobiology
Molecular transcriptional mechanisms in learning/memory and neurological disorders
Disease Mechanisms    Fundamental Cellular Mechanisms 

Lori McMahon, Ph.D. - Cell, Developmental and Integrative Biology
Synaptic plasticity and hippocampal dependent learning

Joseph L. Messina, Ph. D. - Pathology
Insulin and growth hormone (GH) action; insulin and GH resistance following trauma and infection 
Disease Mechanisms    Fundamental Cellular Mechanisms

Michael A. Miller, Ph.D. - Cell, Developmental and Integrative Biology
Function and evolution of intercellular communication mechanisms
Birth Defects & Development    Fundamental Cellular Mechanisms

John Mountz, M.D., Ph.D. - Medicine
Gene therapy, T-cell aging, immunogenetics, and T-cell imaging
Disease Mechanisms

Karolina Mukhtar, Ph.D. - Biology
Molecular mechanisms of cellular stress responses in model plant Arabidopsis thaliana.

Joanne Murphy-Ullrich, Ph.D. - Pathology
Extracellular matrix control of cell and growth factor function
Disease Mechanisms    Fundamental Cellular Mechanisms

Dobrawa Napierala, Ph.D. - Oral and Maxillofacial Surgery

Diana Noah, Ph.D. - Biochemistry/SRI
Understanding of influenza virus pathogenesis, including the mechanisms utilized by the highly pathogenic avian influenza strains causing deaths throughout Asia

Thomas T. Norton, Ph. D. - Vision Sciences
Animal models of myopia: Retinal control of eye size 
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms

Susan Nozell, Ph.D. - Cell, Developmental and Integrative Biology
Disease Mechanisms  Fundamental Cellular Mechanisms

Michelle L. Olsen, Ph.D. - Cell, Developmental and Integrative Biology
Glial potassium channels and glutamate transporters in injury and abnormal development

Suzanne Oparil, M.D. - Medicine
Molecular and cellular mechanisms of cardiovascular disease
Disease Mechanisms    Fundamental Cellular Mechanisms

John Parant, Ph.D. - Pharmacology & Toxicology
Regulation as well as cause of genomic instability in cancer and other diseases
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms

Vladimir Parpura, M.D., Ph.D. - Neurobiology
The role of glial cells in physiology of nervous system
Birth Defects & Development    Disease Mechanisms

Andrew J. Paterson, Ph.D. - Medicine
The role of O-glycosylation in cell regulation and development
Fundamental Cellular Mechanisms

Emma Perez-Costas, Ph.D. - Psychaitry - Behavioral Neurobiology
neuroanatomy, neuropathology, dopamine systems, neurobiology, neuronal development, neurological disorders, neuropsychiatric disorders

Steven Pogwizd, M.D. - Medicine
The electrophysiological and biochemical mechanisms underlying lethal arrhythmias in the setting of heart failure

Selvarangan Ponnazhagan, Ph.D. - Pathology
Adeno-associated virus gene therapy
Disease Mechanisms   Fundamental Cellular Mechanisms

Kirill M. Popov, Ph.D. - Biochemistry & Molecular Genetics
Regulation of pyruvate dehydrogenase complex
Fundamental Cellular Mechanisms

Edward M. Postlethwait, Ph.D. - Environmental Health Sciences
Environmental induction of pulmonary epithelial injury
Birth Defects & Development   Disease Mechanisms

Lucas Pozzo-Miller, Ph.D. - Neurobiology
Neurotrophins; Ca2+ signaling; synapse development and plasticity; mental retardation; Rett syndrome
Fundamental Cellular Mechanisms

Peter Prevelige, Jr., Ph.D. - Microbiology
Structural biology of viral assembly and infection
Disease Mechanisms    Fundamental Cellular Mechanisms

Chandler Raman, Ph.D. - Medicine
Lymphocyte activation, immune tolerance, and autoimmunity tolerance and autoimmunity
Disease Mechanisms

Sasanka Ramanadham, Ph.D. - Cell, Developmental and Integrative Biology 
Beta-cell apoptosis bone metabolism insulin resistance/diabetes
Disease Mechanisms    Fundamental Cellular Mechanisms

Erik Roberson, M.D. Ph.D. - Neurology
Neurobiology of Alzheimer's disease and frontotemporal dementia
Disease Mechanisms    Fundamental Cellular Mechanisms

Tom Ryan Ph.D. - Biochemistry & Molecular Genetics
Stem cell therapies in animal models of human disease

Rajeev Samant, Ph.D. - Pathology
Tumor progression and metastasis of cancer

Ralph D. Sanderson, Ph.D. - Pathology
Molecular regulation of the tumor microenvironment
Disease Mechanisms 

Lisa Schwiebert, Ph.D. - Cell, Developmental and Integrative Biology
Airway inflammation; lung function; asthma and exercise
Disease Mechanisms 

Rosa Serra, Ph.D. - Cell, Developmental and Integrative Biology
Mechanism of TGF-action in developmental and disease processes
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms 

Bingdong Sha, Ph.D. - Cell, Developmental and Integrative Biology
Structural and functional studies of proteins involved in protein folding and translocations
Disease Mechanisms    Fundamental Cellular Mechanisms 

John Shacka, Ph.D. - Pathology
Regulation of neuron death by the autophagy lysosome pathway
Disease Mechanisms    Fundamental Cellular Mechanisms 

Anath Shalev, M.D. - Med - Endrocrinology, Diabetes & Metabolism
Disease Mechanisms

Lalita Shevde-Samant, Ph.D. - Pathology
Mechanisms that regulate tumor progression, metastasis and drug resistance; crosstalk between the tumor cells and their microenvironment

Sadeep Shrestha, Ph.D. - Epidemiology
Infectious disease epidemiology; genetic epidemiology

Peter Smith, Ph.D. - Cell, Developmental and Integrative Biology
The role of the membrane cytoskeleton in regulating the cell surface expression of epithelial transport proteins
Fundamental Cellular Mechanisms

Harald Sontheimer, Ph.D. - Neurobiology
The role of neuroglia in brain function and disease
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms

Eric Sorscher, M.D. - Medicine
Cystic Fibrosis and Molecular Genetics; Patient Oriented Research

Giuseppe L. Squadrito, Ph.D. - Environmental Health Sciences
Development, design and evaluation of dynamic multi-component molecular systems that can be used to understand

David Sweatt, Ph.D. - Neurobiology
Signal transduction mechanisms in learning and memory
Disease Mechanisms    Fundamental Cellular Mechanisms

Elizabeth Sztul, Ph.D. - Cell, Developmental and Integrative Biology
Membrane traffic; protein degradation

Victor John Thannickal, M.D. - Medicine, Pulmonary
Cellular/molecular mechanisms of lung repair and regeneration; Regulation of mesenchymal cell phenotypes; Reactive oxygen species (ROS)-generating NADPH oxidases (NOX) enzymes

Anne Theibert, Ph.D. - Neurobiology
Role of phosphoinositides in developmental neurobiology
Birth Defects & Development    Disease Mechanisms 

Sunnie Thompson, Ph.D. - Microbiology
Translation initiation during viral infection, tumorigenesis, or under stress
Disease Mechanisms    Fundamental Cellular Mechanisms 

Janusz Tucholski, Ph.D. - Psychiatry & Behavioral Neurobiology
Cellular and molecular biology of neuroblastoma; response of neuronal cells and neurons to stress
Disease Mechanisms    Fundamental Cellular Mechanisms 

Thomas Van Groen, Ph.D. - Cell, Developmental and Integrative Biology
Amyloid angiopathy in cognitive dysfunction and Alzheimer's disease
Disease Mechanisms    Fundamental Cellular Mechanisms 

Kristina Visscher, Ph.D. - Neurobiology
Cognitive neuroscience

Jacques Wadiche, Ph.D. - Neurobiology
Synaptic transmission and glutamate transporters
Fundamental Cellular Mechanisms 

Linda Wadiche, Ph.D. - Neurobiology
The function of adult generated neurons
Birth Defects & Development    Fundamental Cellular Mechanisms 

Hengbin Wang, Ph.D. - Biochemistry & Molecular Genetics
Role of histone modification in chromatin function
Fundamental Cellular Mechanisms

Jianbo Wang, Ph.D. - Cell, Developmental and Integrative Biology
A novel signaling pathway termed planar cell polarity (PCP) pathway and how this pathway regulates morphogenesis in mammals
Birth Defects & Development    Fundamental Cellular Mechanisms

Lizhong Wang, M.D., Ph.D. - Genetics
Cancer genetics and molecular epidemiology involved in prostate cancer and breast cancer

Qin Wang, M.D., Ph.D. - Cell, Developmental and Integrative Biology
Regulation of GPCR cellular responses and in vivo functions
Disease Mechanisms 

Adam Wende, Ph.D. - Pathology
Mechanisms of glucose mediated egulation of cardiac mitochondrial function

Andrew B. West, Ph.D. - Neurobiology
Genetic and biochemical mechanisms in neurological disorders
Disease Mechanisms    Fundamental Cellular Mechanisms 

C. Roger White, Ph.D. - Medicine/Cardiovascular Disease
Oxidant stress and endothelial dysfunction
Disease Mechanisms    Fundamental Cellular Mechanisms

Richard Whitley, M.D. - Pediatrics
Antiviral therapies directed against medically important viral diseases of children and adults and the translation of molecular biology to clinical application

Timothy M. Wick, Ph.D. - Biomedical Engineering
Orthopaedic and cardiovascular tissue engineering and regenerative medicine

Scott Wilson, Ph.D. - Neurobiology
Mouse models of neurodegeneration
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanisms 

J. Michael Wyss, Ph.D. - Cell, Developmental and Integrative Biology
Neuroplasticity in aging and neuro cardiovascular control
Disease Mechanisms 

Eddy Yang, M.D., Ph.D. - Radiation Oncology
The targeting of DNA repair pathways to enhance the therapeutic ratio
Disease Mechanisms    Fundamental Cellular Mechanisms 

Qinglin Yang, Ph.D. - Nutrition Sciences
Exploring molecular mechanisms underlying the development and progression of heart failure, especially those related to transcriptional regulation of myocardial fatty acid and carbohydrate metabolisms (eg., PPAR signaling pathway) in pathological conditions such as hypertension, obesity, and diabetes.
Disease Mechanisms    Fundamental Cellular Mechanisms

Yang Yang, M.D., Ph.D. - Molecular and Cellular Pathology
Tumor microenvironment; cancer-related bone diseases; translational research on multiple myeloma
Disease Mechanisms

Xincheng Yao, Ph.D. - Biomedical Engineering
Development of biomedical optics instruments, biophysical study of neural systems, and functional imaging of the retina

Bradley Yoder, Ph.D. - Cell, Developmental and Integrative Biology
Cilia signaling and dysfunction in development and disease
Birth Defects & Development    Disease Mechanisms    Fundamental Cellular Mechanism

Martin E. Young, Ph.D. - Medicine/Cardiovascular Disease
Role of the circadian clock within the heart

Nabiha Yusuf, Ph.D. - Dermatology
Environmental influences such as chemical carcinogens and ultraviolet light on the skin and on the immune system
Disease Mechanisms 

Majd Zayzafoon, M.D., Ph.D. - Pathology
The role of calcium signaling in the genetic and epigenetic pathogenesis of disease
Disease Mechanisms 

Jianhua Zhang, Ph.D. - Pathology
Cell and molecular mechanisms; mouse models of autophagy in development; neurological and psychiatric diseases
Disease Mechanisms    Fundamental Cellular Mechanisms

Xinyang Zhao, Ph.D. - Biochemistry & Molecular Genetics
The roles of protein arginine methyltransferases in abnormal hematopiesis

Yang Yang, M.D., Ph.D. - Molecular and Cellular Pathology
Tumor microenvironment; cancer-related bone diseases; translational research on multiple myeloma
Disease Mechanisms

Lufang Zhou, Ph.D. - Medicine
Oxidative stress induced mitochondrial dysfunction and cardiovascular disease

Kurt Zinn, D.V.M., M.S., Ph.D. - Radiology
The development of imaging approaches that can monitor molecular events in small animal models, particularly technologies that have the potential to translate to human applications are emphasized. Areas of interest include: (1) strategies to link blood-based screening with imaging for early detection of disease, especially cancer, and (2) imaging of protein-protein interactions.