Faculty & Research
Faculty in the CMDB theme are affiliated with multiple departments across UAB. The scientific interests of the faculty are very diverse and interdisciplinary in nature and encompass cell, molecular, and developmental biology using modern tools and approaches as well as a wide range of model organisms and cell culture systems. The research conducted by CMDB faculty addresses fundamental cellular and molecular questions that provide the basis for understanding and treating human disease and developmental abnormalities. Specific research activities of the CMDB faculty can be viewed by visiting individual faculty research and profile pages or by looking under the faculty research focus areas. CMDB faculty research is supported by awards from various agencies, with the majority coming from the National Institutes of Health.
Click on the research focus area in the menu bar on the left to see a listing of faculty members by research focus area.
Fundamental Cellular Mechanisms
Anupam Agarwal, M.D. - Medicine
Regulation of heme oxygenase gene expression in kidney and vascular injury
Disease Mechanisms Fundamental Cellular Mechanisms
Jonas Almeida, Ph.D.- Pathology
Informatics; personalized medicine; systems biology; mathematical modeling
Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
G. M. Anantharamaiah, Ph.D. - Medicine
Apolipoproteins; amphipathic helices; atherosclerosis
Disease Mechanisms Fundamental Cellular Mechanisms
Daniel Balkovetz - Medicine
Epithelial cell biology; epithelial cell signal regulation; regulation of paracellular transport across epithelial cell
Disease Mechanisms Fundamental Cellular Mechanisms
Scott Ballinger, Ph.D. - Molecular and Cellular Pathology
Environmental cardiology; free radical biology; mitochondrial function
Disease Mechanisms Fundamental Cellular Mechanisms
Membrane protein biogenesis in epithelial cells (CFTR as model); unfolded protein response
Disease Mechanisms Fundamental Cellular Mechanisms
Mechanism of translation termination; therapies to suppress stop mutations
Disease Mechanisms Fundamental Cellular Mechanisms
The CFTR chloride channel control of epithelial sodium channel under physiological and pathological conditions Disease Mechanisms Fundamental Cellular Mechanisms
Cellular and molecular physiology of acid-base transporters and pH regulation Disease Mechanisms Fundamental Cellular Mechanisms
Molecular and cellular neurobiology; function of neuronal calcium sensors in health and disease Disease Mechanisms Fundamental Cellular Mechanisms
Molecular studies of astrocytes in health and disease Disease Mechanisms Fundamental Cellular Mechanisms
Lymphocyte development and function Disease Mechanisms Fundamental Cellular Mechanisms
Signaling transduction in development and diseases Birth Defects & Development Fundamental Cellular Mechanisms
Mechanism and regulation of mammalian mRNA turnover
Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Louise Chow, Ph.D. - Biochemistry & Molecular Genetics
Human papillomavirus DNA replication and pathogenesis Disease Mechanisms Fundamental Cellular Mechanisms
James Collawn, Ph.D. - Cell, Developmental and Integrative Biology
Cystic fibrosis; endocytosis; protein trafficking Disease Mechanisms Fundamental Cellular Mechanisms
Rita Cowell, Ph.D. - Psychiatry & Behavioral Neurobiology
Transcriptional regulation of early postnatal brain development: Insights into the pathology of autism and schizophrenia Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Charles Falany, Ph.D. - Pharmacology & Toxicology
Biochemical and physiological properties of human cytosolic sulfotransferases Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
John L. Hartman, IV, M.D. - Genetics
Quantitative analysis of genotype-phenotype interaction networks in yeast models of human disease Fundamental Cellular Mechanisms
Mohammad Hassan, Ph.D. - Oral and Maxillofacial Surgery
The regulation of bone formation and craniofacial development by non-coding microRNA. My research will also explore the role of specific microRNAs for the progression of osteoarthritis. Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Hui-Chen Hsu, Ph.D. - Clinical Immunology, Rheumatology
The BXD2 autoimmune mouse model of lupus and erosive arthritis Disease Mechanisms Fundamental Cellular Mechanisms
Amjad Javed, Ph.D. - Oral and Maxillofacial Surgery
Genetic and molecular signaling for cellular differentiation and skeletogenesis Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Birth Defects & Development Fundamental Cellular Mechanisms
Jeonga Kim - Medicine
Cross-talk between inflammation and insulin signaling Disease Mechanisms Fundamental Cellular Mechanisms
Gwendalyn King, Ph.D. - Neurobiology
Understanding the difference between pathological and non-pathological brain aging Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Adrienne Lahti, M.D. - Psychiatry & Behavioral Neurobiology
Use of multimodal brain imaging techniques to study the neuropathology of schizophrenia and bipolar disorder and to evaluate the effects of psychotopropic drugs on brain function and biochemistry; translational work aiming at bridging human brain imaging and postmortem studies Disease Mechanisms Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Farah Lubin, Ph.D. - Neurobiology
Molecular transcriptional mechanisms in learning/memory and neurological disorders Disease Mechanisms Fundamental Cellular Mechanisms
Jin-Biao Ma, Ph.D. - Biochemistry & Molecular Genetics
Structure and mechanism of proteins-RNA recognition in small RNA biogenesis and regulation Fundamental Cellular Mechanisms
Joseph L. Messina, Ph. D. - Pathology
Insulin and growth hormone (GH) action; insulin and GH resistance following trauma and infection Disease Mechanisms Fundamental Cellular Mechanisms
Michael A. Miller, Ph.D. - Cell, Developmental and Integrative Biology
Function and evolution of intercellular communication mechanisms Birth Defects & Development Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
John Parant, Ph.D. - Pharmacology & Toxicology
Regulation as well as cause of genomic instability in cancer and other diseases Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Ji-Bin Peng, Ph.D. - Medicine
Calcium transport proteins and their roles in health and disease Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Lucas Pozzo-Miller, Ph.D. - Neurobiology
Neurotrophins; Ca2+ signaling; synapse development and plasticity; mental retardation; Rett syndrome Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Sasanka Ramanadham, Ph.D. - Cell, Developmental and Integrative Biology
Beta-cell apoptosis bone metabolism insulin resistance/diabetes Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Rosa Serra, Ph.D. - Cell, Developmental and Integrative Biology
Mechanism of TGF-action in developmental and disease processes Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Bingdong Sha, Ph.D. - Cell, Developmental and Integrative Biology
Structural and functional studies of proteins involved in protein folding and translocations Disease Mechanisms Fundamental Cellular Mechanisms
John Shacka, Ph.D. - Pathology
Regulation of neuron death by the autophagy lysosome pathway Disease Mechanisms Fundamental Cellular Mechanisms
Peter Smith, Ph.D. - Cell, Developmental and Integrative Biology
The role of the membrane cytoskeleton in regulating the cell surface expression of epithelial transport proteins Fundamental Cellular Mechanisms
Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Sunnie Thompson, Ph.D. - Microbiology
Translation initiation during viral infection, tumorigenesis, or under stress Disease Mechanisms Fundamental Cellular Mechanisms
Janusz Tucholski, Ph.D. - Psychiatry & Behavioral Neurobiology
Cellular and molecular biology of neuroblastoma; response of neuronal cells and neurons to stress Disease Mechanisms Fundamental Cellular Mechanisms
Thomas Van Groen, Ph.D. - Cell, Developmental and Integrative Biology
Amyloid angiopathy in cognitive dysfunction and Alzheimer's disease Disease Mechanisms Fundamental Cellular Mechanisms
Fundamental Cellular Mechanisms
Birth Defects & Development Fundamental Cellular Mechanisms
Hengbin Wang, Ph.D. - Biochemistry & Molecular Genetics
Role of histone modification in chromatin function Fundamental Cellular Mechanisms
Jianbo Wang, Ph.D. - Cell, Developmental and Integrative Biology
A novel signaling pathway termed planar cell polarity (PCP) pathway and how this pathway regulates morphogenesis in mammals Birth Defects & Development Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Disease Mechanisms Fundamental Cellular Mechanisms
Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Eddy Yang, M.D., Ph.D. - Radiation Oncology
The targeting of DNA repair pathways to enhance the therapeutic ratio Disease Mechanisms Fundamental Cellular Mechanisms
Qinglin Yang, Ph.D. - Nutrition Sciences
Exploring molecular mechanisms underlying the development and progression of heart failure, especially those related to transcriptional regulation of myocardial fatty acid and carbohydrate metabolisms (eg., PPAR signaling pathway) in pathological conditions such as hypertension, obesity, and diabetes Disease Mechanisms Fundamental Cellular Mechanisms
Bradley Yoder, Ph.D. - Cell, Developmental and Integrative Biology
Cilia signaling and dysfunction in development and disease Birth Defects & Development Disease Mechanisms Fundamental Cellular Mechanisms
Jianhua Zhang, Ph.D. - Pathology
Cell and molecular mechanisms; mouse models of autophagy in development; neurological and psychiatric diseases Disease Mechanisms Fundamental Cellular Mechanisms
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Faculty & Research