Publications


Associations between Abnormal Rod-Mediated Dark Adaptation and Health and Functioning in Older Adults with Normal Macular Health.
Owsley C, Huisingh C, Jackson GR, Curcio CA, Szalai AJ, Dashti N, Clark ME, Rookard K, McCrory MA, Wright TT, Callahan MA, Kline LB, Witherspoon CD, McGwin G Jr.
Invest Ophthalmol Vis Sci. 2014 May 22. pii: IOVS-14-14502. doi: 10.1167/iovs. 14-14502 [Epub ahead of print]

Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines.
Anderson JC, Duarte CW, Welaya K, Rohrbach TD, Bredel M, Yang ES, Choradia NV, Thottassery JV, Yancey Gillespie G, Bonner JA, Willey CD.
Radiother Oncol. 2014 May 8. pii: S0167-8140(14)00173-X. doi: 10.1016/j.radonc.2014.04.010 [Epub ahead of print]
PMID: 24813092 [PubMed - as supplied by publisher]

Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway.
Bowers NL, Helton ES, Huijbregts RP, Goepfert PA, Heath SL, Hel Z.
PLos Pathog. 2014 Mar 13;10(3):e1003993. doi: 10.1371/journal.ppat.1003993. eCollection 2014 Mar.
PMID: 24626392 [PubMed - in process]

Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs.
Huijbregts RP, Michel KG, Hel Z.
Contraception. 2014 Feb 26. pii: S0010-7824(14)00053-5. doi:10.1016/j.contraception.2014.02.006. [Epub ahead of print]
PMID: 24674041 [PubMed - as supplied by publisher]

IFNγ inhibits TH17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms.
Yeh WI, McWilliams IL, Harrington LE.
J Neuroimmunol. 2014 Feb 15;267(1-2):20-7. doi: 10.1016/j.jneuroim.2013.12.001.Epub 2013 Dec 12.
PMID: 24369297 [PubMed - indexed for MEDLINE]

Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
Liu Y, Holdbrooks AT, De Sarno P, Rowse AL, Yanagisawa LL, McFarland BC, Harrington LE, Raman C, Sabbaj S, Benveniste EN, Qin H.
J Immunol. 2014 Jan 1;192(1):59-72. doi: 10.4049/jimmunol.1301513. Epub 2013 Dec 9.
PMID: 243223580 [PubMed - indexed for MEDLINE]

Eosinophil deficiency compromises lung defense against Aspergillus fumigatus.
Lilly LM, Scopel M, Nelson MP, Burg AR, Dunaway CW, Steele C.
Infect Immun. 2013 DEc 30. [Epub ahead of print]
PMID: 24379296 [PubMed - as supplied by publisher]

Innate IFNγ-producing B cells.
Ballesteros-Tato A, Stone SL, Lund FE.
Cell Res. 2013 Dec 17. doi: 10.1038/cr.2013.163. [Epub ahead of print]
PMID: 24343577 [PubMed - as supplied by publisher]

Chlorine gas exposure increases susceptibility to invasive lung fungal infection.
Gessner MA, Doran SF, Yu Z, Dunaway CW, Matalon S, Steele C.
Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;204(11):L765-73. doi: 10.1152/ajplung.00030.2013. Epub 2013 Apr 5.
PMID: 23564508 [PubMed - indexed for MEDLINE]

Experimental Cerebral Malaria Develops Independently of Endothelial Expression of Intercellular Adhesion Molecule-1 (ICAM-1).
Ramos TN, Bullard DC, Darley MM, McDonald K, Crawford DF, Barnum SR.
J Biol Chem. 2013 Mar 14. [Epub ahead of print]
PMID: 23493396 [PubMed - as supplied by publisher]

C-reactive protein exacerbates renal ischemia-reperfusion injury.
Pegues MA, McCrory MA, Zarjou A, Szalai AJ.
Am J Physiol Renal Physiol. 2013 Jun1;304(11):F1358-65. doi: 10.1152/ajprenal.00476.2012. Epub 2013 Mar 27.
PMID: 23535585 [PubMed - indexed for MEDLINE]

Therapeutic inhibition of the alternative complement pathway attenuates chronic EAE.
Hu X, Holers VM, Thurman JM, Schoeb TR, Ramos TN, Barnum SR.
Mol Immunol. 2013 Jan 18;54(3-4):302-308. doi: 10.1016/j.molimm.2012.12.018. Epub 2013 Jan 20.
PMID: 23337717 [PubMed - indexed for MEDLINE]

Hormonal Contraception and HIV-1 Infection: Medroxyprogesterone Acetate Suppresses Innate and Adaptive Immune Mechanisms.
Huijbregts RP, Helton ES, Michel KG, Sabbaj S, Richter HE, Goepfert PA, Hel Z.
Endocrinology. 2013 Mar;154(3):1282-95. doi: 10.1210/en.2012-1850. Epub 2013 Jan 25.
PMID: 23354099 [PubMed - indexed for MEDLINE]

The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis.
Padgett LE, Broniowska KA, Hansen PA, Corbett JA, Tse HM.
Ann N Y Acad Sci. 2013 Jan 16. doi: 10.1111/j.1749-6632.2012.06826.x. [Epub ahead of print]
PMID: 23323860 [PubMed - as supplied by publisher]

SOCS3 deficiency promotes M1 macrophage polarization and inflammation.
Qin H, Holdbrooks AT, Liu Y, Reynolds SL, Yanagisawa LL, Benveniste EN.
J Immunol. 2012 Oct 1;189(7):3439-48. Epub 2012 Aug 27.
PMID: 22925925 [PubMed - indexed for MEDLINE]

AMP-Activated Protein Kinase Restricts IFN-γ Signaling.
Mears GP, Qin H, Liu Y, Holdbrooks AT, Benveniste EN.
J Immunol. 2013 Jan 1:190(1):372-80.doi: 10.4049/jimmunol.1202390. Epub 2012 Nov 23.
PMID: 23180823 [PubMed - indexed for MEDLINE]

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria.
Basu R, O'Quinn DB, Silberger DJ, Schoeb TR, Fouser L, Ouyang W, Hatton RD, Weaver CT.
Immunity. 2012 Dec 14;37(6):1061-75. doi: 10.1016/j.immuni.2012.08.024. Epub 2012 Nov 29.
PMID: 23200827 [PubMed - indexed for MEDLINE]

The β-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22.
Lilly LM, Gessner MA, Dunaway CW, Metz AE, Schwiebert L, Weaver CT, Brown GD, Steel C.
J Immunol. 2012 Oct 1;189(7):3653-60. Epub 2012 Aug 29.
PMID: 22933634 [PubMed - indexed for MEDLINE]

Host Factor Transcriptional Regulation Contributes to Preferential Expression of HIV Type 1 in IL-4-Producing CD4 T Cells.
Zhang M, Clausell A, Robinson T, Yin J, Chen E, Johnson L, Weiss G, Sabbaj S, Lowe RM, Wagner FH, Goepfert PA, Kutsch O, Cron RQ.
J Immunol. 2012 Sep 15;189(6):2746-57. doi: 10.4049/jimmunol.1103129. Epub 2012 Aug 8.
PMID: 22875803 [PubMed - indexed for MEDLINE]

Inflammasome Activation of IL-1 Family Mediators in Response to Cutaneous Photodamage (†).
Nasti TH, Timares L.
Photochem Photobiol. 2012 Sep;88(5):1111-25. doi: 10.1111/j.1751-1097.2012.01182.x. Epub 2012 Jul 9.
PMID: 22631445 [PubMed - in process]

Deletion of the Complement Phagocytic Receptors CR3 and CR4 Does Not Alter Susceptibility to Experimental Cerebral Malaria.
Ramos, TN, Bullard DC, Barnum SR.
Parasite Immunol. 2012 Nov;34(11):547-50. doi: 10.1111/pim.12002. 
PMID: 22882618 [PubMed - indexed for MEDLINE]

The C5 convertase is not required for activation of the terminal complement pathway in murine experimental cerebral malaria.
Ramos TN, Darley MM, Weckbach S, Stahel PF, Tomlinson S, Barnum SR.
J Biol Chem. 2012 Jul 13;287(29):24734-8. Epub 2012 Jun 11.
PMID: 22689574 [PubMed - indexed for MEDLINE]

Deletion of Carboxypeptidase N Delays Onset of Experimental Cerebral Malaria.
Darley MM, Ramos TN, Wetsel RA, Barnum SR.
Parasite Immunol. 2012 June 18. doi: 10.1111/j.1365-3024.2012.01376.x. [Epub ahead of print]
PMID: 22708514 [PubMed - as supplied by publisher]

Regulation of Toll-like Receptor 5 Gene Expression and Function on Mucosal Dendritic Cells.
Feng T, Cong Y, Alexander K, Elson CO.
PLoS One. 2012;7(4):e35918. Epub 2012 Apr 24.
PMID: 22545147 [PubMed - indexed for MEDLINE] Free PMC Article

MARCKS regulates growth and radiation sensitivity and is a novel prognostic factor for glioma.
Jarboe JS, Anderson JC, Duarte CW, Mehta T, Nowsheen S, Hicks PH, Whitley AC, Rohrbach TD, McCubrey RO, Chiu S, Burleson TM, Bonner JA, Gillespie GY, Yang ES, Willey CD.
Clin Cancer Res. 2012 Jun 1;18(11):3030-41. Epub 2012 May 22.
PMID: 22619307 [PubMed - indexed for MEDLINE]

Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice.
Seleme MC, Lei W, Burg AR, Goh KY, Metz A, Steele C, Tse HM.
Free Radic Biol Med. 2012 May 1;52(9):2047-56. Epub 2012 Feb 4.
PMID: 22361747 [PubMed - in process]

Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation.
Qin H, Yeh WI, De Sarno P, Holdbrooks AT, Liu Y, Muldowney MT, Reynolds SL, Yanagisawa LL, Fox TH 3rd, Park K, Harrington LE, Raman C, Benveniste EN.
Proc Natl Acad Sci U S A. 2012 Mar 27;109(13):5004-9. Epub 2012 Mar 12.
PMID: 22411837 [PubMed - indexed for MEDLINE]

Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice.
Naseemuddin M, Iqbal A, Nasti TH, Ghandhi JL, Kapadia AD, Yusuf N.
Int J Cancer. 2012 Feb 15; 130(4):765-74 doi: 10.1002/ijc.26100. Epub 2011 Jun 18.
PMID: 21455984 [PubMed - indexed for MEDLINE]

Dectin-1-dependent interleukin-22 contributes to early innate lung defense against Aspergillus fumigatus.
Gessner MA, Werner JL, Lilly LM, Nelson MP, Metz AE, Dunaway CW, Chan YR, Ouyang W, Brown GD, Weaver CT, Steele C.
Infect Immun. 2012 Jan;80(1):410-7. Epub 2011 Oct 28.
PMID: 22038916 [PubMed - indexed for MEDLINE]

Autoreactive Tbet-positive CD4 T cells develop independent of classic Th1 cytokine signaling during experimental autoimmune encephalomyelitis.
Yeh WI, McWilliams IL, Harrington LE.
J Immunol. 2011 Nov 15; 187(10):4998-5006. Epub 2011 Oct 7.
PMID: 21984703 [PubMed - indexed for MEDLINE]

Neutrophils produce IL-17A in a Dectin-1 and IL-23 dependent manner during invasive fungal infection.
Werner JL, Gessner MA, Lilly LM, Nelson MP, Metz AE, Horn D, Dunaway CW, Deshane J, Chaplin DD, Weaver CT, Brown GD, Steele C.
Infect Immun. 2011 Oct; 79(10):3966-77. Epub 201 Aug 1.
PMID: 21807912 [PubMed - indexed for MEDLINE]

The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma.
Mojib N, Nasti TH, Andersen DT, Attigada VR, Hoover RB, Yusuf N, Bej AK.
Int J Dermatol. 2011 Oct;50(10):1223-33. doi: 10.1111/j.1365-4632.2010.04825x. Epub 2011 Jul 26.
PMID: 21790550 [PubMed - indexed for MEDLINE]

Collagen-induced arthritis is exacerbated in C-reactive protein-deficient mice.
Jones NR, Pegues MA, McCrory MA, Kerr SW, Jiang H, Sellati R, Berger V, Villalona J, Parikh R, McFarland M, Pantages L, Madwed JB, Szalai AJ.
Arthritis Rheum. 2011 Sep;63(9):2641-50. doi: 10.1002/art.30444.
PMID: 21567377 [PubMed - indexed for MEDLINE] PMCID:PMC3168703

Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.
Thayer TC, Delano M, Liu C, Chen J, Padgett LE, Tse HM, Annamali M, Piganelli JD, Moldawer LL, Mathews CE.
Diabetes. 2011 Aug;60(8):2144-51. Epub 2011 Jun 29.
PMID: 21715554 [PubMed - indexed for MEDLINE] PMCID:PMC3142064

Cutting Edge: The Membrane Attack Complex of Complement Is Required for the Development of Murine Experimental Cerebral Malaria.
Ramos TN, Darley MM, Hu X, Billker O, Rayner JC, Ahras M, Wohler JE, Barnum SR
J Immunol. 2011 May 13. [Epub ahead of print]
PMID: 21572031 [PubMed - as supplied by publisher]