Core Curriculum

Graduate Biomedical Sciences Core Curriculum

 

Block 1 - Biochemistry/Metabolism

 

  • Amino acids and primary protein structure
  • Protein secondary and tertiary structure
  • Postranslational modifications and allosteric changes
  • Glycobiology
  • Lipid structure and metabolism
  • Thermodynamic principles of biochemical reactions
  • Enzyme kinetics
  • Enzyme mechanisms and regulation
  • Amino acid/nitrogen metabolism
  • Glycolysis, gluconeogenesis and citric acid cycle
  • Glycogenesis, glycogenolysis and pentose phosphate pathway
  • Electron transport/oxidative phosphorylation

Block 1 2011 Syllabus

 

Block 2 - Genetics/Molecular Biology

  • DNA recombination
  • Nucleic acids & DNA replication
  • Prokaryotic transcription
  • Prokaryotic translation
  • Prokaryotic gene regulation
  • Eukaryotic genome organization
  • Eukaryotic DNA replication
  • Eukaryotic transcription
  • Eukaryotic translation
  • Eukaryotic gene regulation I
  • Eukaryotic gene regulation II
  • Mendelian inheritance
  • Genetic variation and polymorphisms

Block 2 2011 Syllabus

Block 3 - Biological Organization

  • Integrated systems: From organelles to organs
  • Membrane structure/function
  • Cytoskeleton
  • Secretion
  • Endocytosis, lysosomal targeting, protein degradation
  • Biochemistry of signal transduction
  • Cell cycle
  • Cell-cell junctions and polarity
  • ECM and ECM-cell interactions
  • Cell motility
  • Apoptosis
  • Discipline of pharmacology
  • Pharmacokinetics

Block 3 2011 Syllabus