» Selected Publications | Research Grant Awards
March, 2008 Selected Publications
Chanda D, Isayeva T, Kumar S, Siegal GP, Szafran AA, Zinn KR, Reddy VV, Ponnazhagan S.
Systemic Osteoprotegerin Gene Therapy Restores Tumor-induced Bone Loss in a Therapeutic Model of Breast Cancer Bone Metastasis.
Mol Ther. 2008 Mar 18; [Epub ahead of print]
PMID: 18388919 [PubMed - as supplied by publisher]
Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, Debenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM.
Free in PMC
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast Cancer Res Treat. 2008 Mar;108(1):43-55. Epub 2007 May 17.
PMID: 17508279 [PubMed - in process]
Breakefield XO, Blood AJ, Li Y, Hallett M, Hanson PI, Standaert DG.
The pathophysiological basis of dystonias.
Nat Rev Neurosci. 2008 Mar;9(3):222-34. Review.
PMID: 18285800 [PubMed - indexed for MEDLINE]
Byon CH, Javed A, Dai Q, Kappes JC, Clemens TL, Darley-Usmar VM, McDonald JM, Chen Y.
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor runx-2 by akt signaling.
J Biol Chem. 2008 Mar 31; [Epub ahead of print]
PMID: 18378684 [PubMed - as supplied by publisher]
Varga K, Goldstein RF, Jurkuvenaite A, Chen L, Matalon S, Sorscher EJ, Bebok Z, Collawn JF.
Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones.
Biochem J. 2008 Mar 15;410(3):555-64.
PMID: 18052931 [PubMed - indexed for MEDLINE
Raska M, Moldoveanu Z, Novak J, Hel Z, Novak L, Bozja J, Compans RW, Yang C, Mestecky J.
Delivery of DNA HIV-1 vaccine to the liver induces high and long-lasting humoral immune responses.
Vaccine. 2008 Mar 17;26(12):1541-51. Epub 2008 Feb 7.
PMID: 18304708 [PubMed - in process]
Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus WC, Ramakrishnan V, Sarkar D, Shah K, Curiel DT, Grant S, Fisher PB, Dent P.
MDA-7/IL-24 Plus Radiation Enhance Survival in Animals with Intracranial Primary Human GBM Tumors.
Cancer Biol Ther. 2008 Mar 19;7(6) [Epub ahead of print]
PMID: 18376144 [PubMed - as supplied by publisher]
Shanmugam C, Katkoori VR, Jhala NC, Grizzle WE, Siegal GP, Manne U.
p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior.
J Histochem Cytochem. 2008 Mar;56(3):305-12. Epub 2007 Dec 10.
PMID: 18071066 [PubMed - indexed for MEDLINE]
February, 2008 Selected Publications
Gupta P, Emdad L, Lebedeva IV, Sarkar D, Dent P, Curiel DT, Settleman J, Fisher PB.
Targeted combinatorial therapy of non-small cell lung carcinoma using a GST-fusion protein of full-length or truncated MDA-7/IL-24 with Tarceva.
J Cell Physiol. 2008 Feb 12; [Epub ahead of print]
PMID: 18270968 [PubMed - as supplied by publisher]
Saini V, Martyshkin DV, Mirov SB, Perez A, Perkins G, Ellisman MH, Towner VD, Wu H, Pereboeva L, Borovjagin A, Curiel DT, Everts M.
An Adenoviral Platform for Selective Self-Assembly and Targeted Delivery of Nanoparticles.
Small. 2008 Feb 1;4(2):262-269.
PMID: 18200644 [PubMed - as supplied by publisher]
Hsu HC, Yang P, Wang J, Wu Q, Myers R, Chen J, Yi J, Guentert T, Tousson A, Stanus AL, Le TV, Lorenz RG, Xu H, Kolls JK, Carter RH, Chaplin DD, Williams RW, Mountz JD.
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
Nat Immunol. 2008 Feb;9(2):166-75. Epub 2007 Dec 23.
PMID: 18157131 [PubMed - in process]
Kim HG, Kojima K, Swindle CS, Cotta CV, Huo Y, Reddy V, Klug CA.
FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia.
Blood. 2008 Feb 1;111(3):1567-74. Epub 2007 Oct 29.
PMID: 17967943 [PubMed - in process]
Phadke PA, Vaidya KS, Nash KT, Hurst DR, Welch DR.
BRMS1 Suppresses Breast Cancer Experimental Metastasis to Multiple Organs by Inhibiting Several Steps of the Metastatic Process.
Am J Pathol. 2008 Feb 14; [Epub ahead of print]
PMID: 18276787 [PubMed - as supplied by publisher]
January, 2008 Selected Publications
Lewis TB, Standaert DG.
Design of clinical trials of gene therapy in Parkinson disease.
Exp Neurol. 2008 Jan;209(1):41-7. Epub 2007 Aug 31.
PMID: 17920590 [PubMed - in process]
Pereboev A, Borisevich V, Tsuladze G, Shakhmatov M, Hudman D, Kazachinskaia E, Razumov I, Svyatchenko V, Loktev V, Yamshchikov V.
Genetically delivered antibody protects against West Nile virus.
Antiviral Res. 2008 Jan;77(1):6-13. Epub 2007 Sep 14.
PMID: 17904654 [PubMed - in process]
Schoehn G, El Bakkouri M, Fabry CM, Billet O, Estrozi LF, Le L, Curiel DT, Kajava AV, Ruigrok RW, Kremer EJ.
3D structure of canine adenovirus serotype 2 capsid.
J Virol. 2008 Jan 23; [Epub ahead of print]
PMID: 18216088 [PubMed - as supplied by publisher]
Brumlik MJ, Daniel BJ, Waehler R, Curiel DT, Giles FJ, Curiel TJ.
Trends in immunoconjugate and ligand-receptor based targeting development for cancer therapy.
Expert Opin Drug Deliv. 2008 Jan;5(1):87-103.
PMID: 18095930 [PubMed - as supplied by publisher]
Saini V, Martyshkin DV, Mirov SB, Perez A, Perkins G, Ellisman MH, Towner VD, Wu H, Pereboeva L, Borovjagin A, Curiel DT, Everts M.
An Adenoviral Platform for Selective Self-Assembly and Targeted Delivery of Nanoparticles.
Small. 2008 Jan 17; [Epub ahead of print]
PMID: 18200644 [PubMed - as supplied by publisher]
Schierer S, Hesse A, Müller I, Kämpgen E, Curiel DT, Schuler G, Steinkasserer A, Nettelbeck DM.
Modulation of viability and maturation of human monocyte-derived dendritic cells by oncolytic adenoviruses.
Int J Cancer. 2008 Jan 1;122(1):219-29.
PMID: 17764070 [PubMed - indexed for MEDLINE]
Katkoori VR, Jia X, Chatla C, Kumar S, Ponnazhagan S, Callens T, Messiaen L, Grizzle WE, Manne U.
Clinical significance of a novel single nucleotide polymorphism in the 5' untranslated region of the Rabphillin-3A-Like gene in colorectal adenocarcinoma.
Front Biosci. 2008 Jan 1;13:1050-61.
PMID: 17981610 [PubMed - indexed for MEDLINE]
Dulak J, Deshane J, Jozkowicz A, Agarwal A.
Heme oxygenase-1 and carbon monoxide in vascular pathobiology: focus on angiogenesis.
Circulation. 2008 Jan 15;117(2):231-41.
PMID: 18195184 [PubMed - in process]
Numnum TM, Makhija S, Lu B, Wang M, Rivera A, Stoff-Khalili M, Alvarez RD, Zhu ZB, Curiel DT.
Improved anti-tumor therapy based upon infectivity-enhanced adenoviral delivery of RNA interference in ovarian carcinoma cell lines.
Gynecol Oncol. 2008 Jan;108(1):34-41. Epub 2007 Dec 3.
PMID: 18061250 [PubMed - indexed for MEDLINE]
Kendrick JE, Straughn JM Jr, Oliver PG, Wang W, Nan L, Grizzle WE, Stockard CR, Alvarez RD, Buchsbaum DJ.
Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model.
Gynecol Oncol. 2008 Jan 3; [Epub ahead of print]
PMID: 18177927 [PubMed - as supplied by publisher]
December, 2007 Selected Publications
Hanna J, Wernig M, Markoulaki S, Sun CW, Meissner A, Cassady JP, Beard C, Brambrink T, Wu LC, Townes TM, Jaenisch R.
Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin.
Science. 2007 Dec 21;318(5858):1920-3. Epub 2007 Dec 6.
PMID: 18063756 [PubMed - in process]
Kumar S, Ponnazhagan S.
Bone homing of mesenchymal stem cells by ectopic alpha4 integrin expression.
FASEB J. 2007 Dec;21(14):3917-27. Epub 2007 Jul 10.
PMID: 17622670 [PubMed - in process]
Varga K, Goldstein RF, Jurkuvenaite A, Chen L, Matalon S, Sorscher EJ, Bebok Z, Collawn JF.
Enhanced cell surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator by pharmacological chaperones.
Biochem J. 2007 Dec 4; [Epub ahead of print]
PMID: 18052931 [PubMed - as supplied by publisher]
Hsu HC, Yang P, Wang J, Wu Q, Myers R, Chen J, Yi J, Guentert T, Tousson A, Stanus AL, Le TV, Lorenz RG, Xu H, Kolls JK, Carter RH, Chaplin DD, Williams RW, Mountz JD.
Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.
Nat Immunol. 2007 Dec 23; [Epub ahead of print]
PMID: 18157131 [PubMed - as supplied by publisher]
Hill-Kapturczak N, Jarmi T, Agarwal A.
Growth factors and heme oxygenase-1: perspectives in physiology and pathophysiology.
Antioxid Redox Signal. 2007 Dec;9(12):2197-207.
PMID: 17979525
Mitchell C, Park MA, Zhang G, Yacoub A, Curiel DT, Fisher PB, Roberts JD, Grant S, Dent P.
Extrinsic pathway- and cathepsin-dependent induction of mitochondrial dysfunction are essential for synergistic flavopiridol and vorinostat lethality in breast cancer cells.
Mol Cancer Ther. 2007 Dec;6(12):3101-12. Epub 2007 Dec 7.
PMID: 18065490
Derosier LC, Vickers SM, Zinn KR, Huang Z, Wang W, Grizzle WE, Sellers J, Stockard CR Jr, Zhou T, Oliver PG, Arnoletti P, Lobuglio AF, Buchsbaum DJ.
TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.
Mol Cancer Ther. 2007 Dec;6(12):3198-207.
PMID: 18089714
Shanmugam C, Katkoori VR, Jhala NC, Grizzle WE, Siegal GP, Manne U.
p53 Nuclear Accumulation and Bcl-2 Expression in Contiguous Adenomatous Components of Colorectal Adenocarcinomas Predict Aggressive Tumor Behavior.
J Histochem Cytochem. 2007 Dec 10
PMID: 18071066
Berdiev BK, Cormet-Boyaka E, Tousson A, Qadri YJ, Oosterveld-Hut HM, Hong JS, Gonzales PA, Fuller CM, Sorscher EJ, Lukacs GL, Benos DJ.
Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer.
J Biol Chem. 2007 Dec 14;282(50):36481-8. Epub 2007 Oct 3.
PMID: 17913705
November, 2007 Selected Publications
Ungerechts G, Springfeld C, Frenzke ME, Lampe J, Johnston PB, Parker WB, Sorscher EJ, Cattaneo R.
Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine.
Cancer Res. 2007 Nov 15;67(22):10939-47.
PMID: 18006839 [PubMed - in process]
Zhu ZB, Mathis JM, Makhija SK, Lu B, Wang M, Ji S, Rivera AA, Rosenthal EL, Siegal GP, Curiel DT.
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
Int J Oncol. 2007 Nov;31(5):1213-22.
PMID: 17912450 [PubMed - in process]
Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E.
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
J Immunol. 2007 Nov 15;179(10):7079-86.
PMID: 17982099 [PubMed - in process]
Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, Chatman L, Boukerche H, Ramesh R, Inoue S, Chada S, Li R, De Pass AL, Mahasreshti PJ, Dmitriev IP, Curiel DT, Yacoub A, Grant S, Dent P, Senzer N, Nemunaitis JJ, Fisher PB.
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
Int J Oncol. 2007 Nov;31(5):985-1007.
PMID: 17912425 [PubMed - in process]
Wang L, Martin DR, Baker HJ, Zinn KR, Kappes JC, Ding H, Gentry AS, Harper S, Snyder EY, Cox NR.
Neural progenitor cell transplantation and imaging in a large animal model.
Neurosci Res. 2007 Nov;59(3):327-40. Epub 2007 Aug 23.
PMID: 17897743 [PubMed - in process]
Hurst DR, Welch DR.
A MSC-ing link in metastasis?
Nat Med. 2007 Nov;13(11):1289-91. No abstract available.
PMID: 17987025 [PubMed - in process]
Ulasov IV, Rivera AA, Nettelbeck DM, Rivera LB, Mathis JM, Sonabend AM, Tyler M, Wang M, Douglas JT, Lesniak MS.
An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy.
Int J Oncol. 2007 Nov;31(5):1177-85.
PMID: 17912445 [PubMed - in process]
Emdad L, Lebedeva IV, Su ZZ, Sarkar D, Dent P, Curiel DT, Fisher PB.
Melanoma differentiation associated gene-7/interleukin-24 reverses multidrug resistance in human colorectal cancer cells.
Mol Cancer Ther. 2007 Nov;6(11):2985-94.
PMID: 18025283 [PubMed - in process]
Grammatopoulos TN, Outeiro TF, Hyman BT, Standaert DG.
Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.
Biochem Biophys Res Commun. 2007 Nov 23;363(3):846-51. Epub 2007 Sep 21.
PMID: 17900533 [PubMed - in process]
Bansal A, Yue L, Conway J, Yusim K, Tang J, Kappes J, Kaslow RA, Wilson CM, Goepfert PA.
Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescents.
AIDS. 2007 Nov 30;21(18):2387-2397.
PMID: 18025875 [PubMed - as supplied by publisher]
McLerran D, Grizzle WE, Feng Z, Thompson IM, Bigbee WL, Cazares LH, Chan DW, Dahlgren J, Diaz J, Kagan J, Lin D, Malik G, Oelschlager D, Partin A, Randolph T, Sokoll L, Srivastava S, Srivastava S, Thornquist M, Troyer D, Wright GL, Zhang Z, Zhu L, Semmes OJ.
SELDI-TOF MS Whole Serum Proteomic Profiling with IMAC Surface Does Not Reliably Detect Prostate Cancer.
Clin Chem. 2007 Nov 16; [Epub ahead of print]
PMID: 18024530 [PubMed - as supplied by publisher]
October, 2007 Selected Publications
Han T, Tang Y, Ugai H, Perry LE, Siegal GP, Contreras JL, Wu H.
Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy.
Virol J. 2007 Oct 24;4(1):103 [Epub ahead of print]
PMID: 17958897 [PubMed - as supplied by publisher]
Miura Y, Yoshida K, Nishimoto T, Hatanaka K, Ohnami S, Asaka M, Douglas JT, Curiel DT, Yoshida T, Aoki K.
Direct selection of targeted adenovirus vectors by random peptide display on the fiber knob.
Gene Ther. 2007 Oct;14(20):1448-60.
PMID: 17700705 [PubMed - in process]
Berdiev BK, Cormet-Boyaka E, Tousson A, Qadri YJ, Oosterveld-Hut HM, Hong JS, Gonzales PA, Fuller CM, Sorscher EJ, Lukacs GL, Benos DJ.
Molecular proximity of CFTR and ENaC assessed by fluorescence resonance energy transfer.
J Biol Chem. 2007 Oct 3; [Epub ahead of print]
PMID: 17913705 [PubMed - as supplied by publisher]
Pan G, Ahn EY, Chen Y, Feng G, Reddy V, Jhala NC, McDonald JM.
Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma.
Int J Oncol. 2007 Oct;31(4):843-50.
PMID: 17786316 [PubMed - in process]
Gaggar A, Olman MA.
Biologic markers of mortality in acute lung injury.
Clin Chim Acta. 2006 Oct;372(1-2):24-32.
PMID: 16797514 [PubMed - indexed for MEDLINE]
Collard HR, Moore BB, Flaherty KR, Brown KK, Kaner RJ, King TE Jr, Lasky JA, Loyd JE, Noth I, Olman MA, Raghu G, Roman J, Ryu JH, Zisman DA, Hunninghake GW, Colby TV, Egan JJ, Hansell DM, Johkoh T, Kaminski N, Kim DS, Kondoh Y, Lynch DA, Muller-Quernheim J, Myers JL, Nicholson AG, Selman M, Toews GB, Wells AU, Martinez FJ; Idiopathic Pulmonary Fibrosis Clinical Research Network Investigators.
Acute exacerbations of idiopathic pulmonary fibrosis.
Am J Respir Crit Care Med. 2007 Oct 1;176(7):636-43. Epub 2007 Jun 21.
PMID: 17585107 [PubMed - in process]
Seo HS, Serra R.
Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints.
Dev Biol. 2007 Oct 15;310(2):304-16. Epub 2007 Aug 9.
PMID: 17822689 [PubMed - in process]
September, 2007 Selected Publications
Ulasov IV, Rivera AA, Han Y, Curiel DT, Zhu ZB, Lesniak MS.
Targeting adenovirus to CD80 and CD86 receptors increases gene transfer efficiency to malignant glioma cells.
J Neurosurg. 2007 Sep;107(3):617-27.
PMID: 17886563 [PubMed - in process]
Harari PM, Allen GW, Bonner JA.
Biology of interactions: antiepidermal growth factor receptor agents.
J Clin Oncol. 2007 Sep 10;25(26):4057-65.
PMID: 17827454 [PubMed - in process]
Vaidya KS, Welch DR.
Metastasis suppressors and their roles in breast carcinoma.
J Mammary Gland Biol Neoplasia. 2007 Sep;12(2-3):175-90.
PMID: 17587154 [PubMed - in process]
Sawrie SM, Guthrie BL, Spencer SA, Nordal RA, Meredith RF, Markert JM, Cloud GA, Fiveash JB.
Predictors of Distant Brain Recurrence for Patients with Newly Diagnosed Brain Metastases Treated with Stereotactic Radiosurgery Alone.
Int J Radiat Oncol Biol Phys. 2007 Sep 4; [Epub ahead of print]
PMID: 17768015 [PubMed - as supplied by publisher]
Meredith RF, Buchsbaum DJ, Alvarez RD, Lobuglio AF.
Brief overview of preclinical and clinical studies in the development of intraperitoneal radioimmunotherapy for ovarian cancer.
Clin Cancer Res. 2007 Sep 15;13(18):5643s-5s.
PMID: 17875801 [PubMed - in process]
Derosier LC, Oliver PG, Huang ZQ, Sellers JC, Grizzle WE, Wang W, Zhou T, Zinn KR, Long JW, Vickers SM.
Combination Treatment with TRA-8 Anti Death Receptor 5 Antibody and CPT-11 Induces Tumor Regression in an Orthotopic Model of Pancreatic Cancer.
Clin Cancer Res. 2007 Sep 15;13(18):5535s-43s.
PMID: 17875786 [PubMed - in process]
Kojima K, Vickers SM, Adsay NV, Jhala NC, Kim HG, Schoeb TR, Grizzle WE, Klug CA.
Inactivation of Smad4 Accelerates KrasG12D-Mediated Pancreatic Neoplasia.
Cancer Res. 2007 Sep 1;67(17):8121-30.
PMID: 17804724 [PubMed - in process]
Chhieng DC, Rodriguez-Burford C, Meleth S, Grizzle WE, Ferguson SM.
Assessment of biomarker expression in predicting pathologic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.
Breast J. 2007 Sep-Oct;13(5):534-5. No abstract available.
PMID: 17760684 [PubMed - in process]
Yeo H, Beck LH, Thompson SR, Farach-Carson MC, McDonald JM, Clemens TL, Zayzafoon M.
Conditional dysruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption.
J Biol Chem. 2007 Sep 19; [Epub ahead of print]
PMID: 17884821 [PubMed - as supplied by publisher]
August, 2007 Selected Publications
Waehler R, Russell SJ, Curiel DT.
Engineering targeted viral vectors for gene therapy.
Nat Rev Genet. 2007 Aug;8(8):573-87. Epub 2007 Jul 3.
PMID: 17607305 [PubMed - in process]
Ungerechts G, Springfeld C, Frenzke ME, Lampe J, Parker WB, Sorscher EJ, Cattaneo R.
An Immunocompetent Murine Model for Oncolysis with an Armed and Targeted Measles Virus.
Mol Ther. 2007 Aug 21; [Epub ahead of print]
PMID: 17712331 [PubMed - as supplied by publisher]
Buchsbaum DJ, Forero-Torres A, Lobuglio AF.
TRAIL-receptor antibodies as a potential cancer treatment.
Future Oncol. 2007 Aug;3(4):405-409.
PMID: 17661715 [PubMed - as supplied by publisher]
McDonald HM, Pruett PS, Deivanayagam C, Protasevich II, Carson WM, DeLucas LJ, Brouillette WJ, Brouillette CG.
Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
Acta Crystallogr D Biol Crystallogr. 2007 Aug;63(Pt 8):891-905. Epub 2007 Jul 17.
PMID: 17642516 [PubMed - in process]
Lang JD, Teng X, Chumley P, Crawford JH, Isbell TS, Chacko BK, Liu Y, Jhala N, Crowe DR, Smith AB, Cross RC, Frenette L, Kelley EE, Wilhite DW, Hall CR, Page GP, Fallon MB, Bynon JS, Eckhoff DE, Patel RP.
Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation.
J Clin Invest. 2007 Aug 23; [Epub ahead of print]
PMID: 17717604 [PubMed - as supplied by publisher]
Kim GB, Wang Z, Liu YY, Stavrou S, Mathias A, Goodwin KJ, Thomas JM, Neville DM.
A fold-back single-chain diabody format enhances the bioactivity of an anti-monkey CD3 recombinant diphtheria toxin-based immunotoxin.
Protein Eng Des Sel. 2007 Aug 21; [Epub ahead of print]
PMID: 17693455 [PubMed - as supplied by publisher]
Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS.
Survivin-Driven and Fiber-Modified Oncolytic Adenovirus Exhibits Potent Antitumor Activity in Established Intracranial Glioma.
Hum Gene Ther. 2007 Jul 13; [Epub ahead of print]
PMID: 17630837 [PubMed - as supplied by publisher]
Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS.
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models.
Neuro Oncol. 2007 Jul;9(3):280-90. Epub 2007 May 23.
PMID: 17522331 [PubMed - in process]
Kumar S, Ponnazhagan S.
Bone homing of mesenchymal stem cells by ectopic {alpha}4 integrin expression.
FASEB J. 2007 Jul 10; [Epub ahead of print]
Roberts J, Chen B, Curtis LM, Agarwal A, Sanders PW, Zinn KR.
Detection of early changes in renal function using Tc-99m-MAG3 imaging in a murine model of ischemia-reperfusion injury.
Am J Physiol Renal Physiol. 2007 Jul 18; [Epub ahead of print]
PMID: 17634403 [PubMed - as supplied by publisher]
Moeinpour F, Choudhry MA, Kawasaki T, Timares L, Schwacha MG, Bland KI, Chaudry IH.
17beta-Estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage.
Mol Immunol. 2007 Jul;44(13):3317-23. Epub 2007 Apr 2.
PMID: 17403539 [PubMed - in process]
Zhang HG, Kim H, Liu C, Yu S, Wang J, Grizzle WE, Kimberly RP, Barnes S.
Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.
Biochim Biophys Acta. 2007 Jul;1773(7):1116-23. Epub 2007 May 1.
PMID: 17555831 [PubMed - in process]
Chen Y, Pawar P, Pan G, Ma L, Liu H, McDonald JM.
Calmodulin binding to the Fas-Mediated death-inducing signaling complex in cholangiocarcinoma cells.
J Cell Biochem. 2007 Jul 24; [Epub ahead of print]
PMID: 17654480 [PubMed - as supplied by publisher]
Bi LL, Pan G, Atkinson TP, Zheng L, Dale JK, Makris C, Reddy V, McDonald JM, Siegel RM, Puck JM, Lenardo MJ, Straus SE.
Dominant inhibition of Fas ligand-mediated apoptosis due to a heterozygous mutation associated with autoimmune lymphoproliferative syndrome (ALPS) Type Ib.
BMC Med Genet. 2007 Jul 2;8:41.
PMID: 17605793 [PubMed - indexed for MEDLINE]
McCulley A, Morrow CD.
Nucleotides within the anticodon stem are important for optimal use of tRNA(Lys,3) as the primer for HIV-1 reverse transcription.
Virology. 2007 Jul 20;364(1):169-77. Epub 2007 Mar 21.
PMID: 17368706 [PubMed - indexed for MEDLINE]
Yuan K, Chung LW, Siegal GP, Zayzafoon M.
alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.
Lab Invest. 2007 Jul 16; [Epub ahead of print]
PMID: 17632540 [PubMed - as supplied by publisher]
July, 2007 Selected Publications
Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS.
Survivin-Driven and Fiber-Modified Oncolytic Adenovirus Exhibits Potent Antitumor Activity in Established Intracranial Glioma.
Hum Gene Ther. 2007 Jul 13; [Epub ahead of print]
PMID: 17630837 [PubMed - as supplied by publisher]
Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS.
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models.
Neuro Oncol. 2007 Jul;9(3):280-90. Epub 2007 May 23.
PMID: 17522331 [PubMed - in process]
Kumar S, Ponnazhagan S.
Bone homing of mesenchymal stem cells by ectopic {alpha}4 integrin expression.
FASEB J. 2007 Jul 10; [Epub ahead of print]
Roberts J, Chen B, Curtis LM, Agarwal A, Sanders PW, Zinn KR.
Detection of early changes in renal function using Tc-99m-MAG3 imaging in a murine model of ischemia-reperfusion injury.
Am J Physiol Renal Physiol. 2007 Jul 18; [Epub ahead of print]
PMID: 17634403 [PubMed - as supplied by publisher]
Moeinpour F, Choudhry MA, Kawasaki T, Timares L, Schwacha MG, Bland KI, Chaudry IH.
17beta-Estradiol normalizes Toll receptor 4, mitogen activated protein kinases and inflammatory response in epidermal keratinocytes following trauma-hemorrhage.
Mol Immunol. 2007 Jul;44(13):3317-23. Epub 2007 Apr 2.
PMID: 17403539 [PubMed - in process]
Zhang HG, Kim H, Liu C, Yu S, Wang J, Grizzle WE, Kimberly RP, Barnes S.
Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity.
Biochim Biophys Acta. 2007 Jul;1773(7):1116-23. Epub 2007 May 1.
PMID: 17555831 [PubMed - in process]
Chen Y, Pawar P, Pan G, Ma L, Liu H, McDonald JM.
Calmodulin binding to the Fas-Mediated death-inducing signaling complex in cholangiocarcinoma cells.
J Cell Biochem. 2007 Jul 24; [Epub ahead of print]
PMID: 17654480 [PubMed - as supplied by publisher]
Bi LL, Pan G, Atkinson TP, Zheng L, Dale JK, Makris C, Reddy V, McDonald JM, Siegel RM, Puck JM, Lenardo MJ, Straus SE.
Dominant inhibition of Fas ligand-mediated apoptosis due to a heterozygous mutation associated with autoimmune lymphoproliferative syndrome (ALPS) Type Ib.
BMC Med Genet. 2007 Jul 2;8:41.
PMID: 17605793 [PubMed - indexed for MEDLINE]
McCulley A, Morrow CD.
Nucleotides within the anticodon stem are important for optimal use of tRNA(Lys,3) as the primer for HIV-1 reverse transcription.
Virology. 2007 Jul 20;364(1):169-77. Epub 2007 Mar 21.
PMID: 17368706 [PubMed - indexed for MEDLINE]
Yuan K, Chung LW, Siegal GP, Zayzafoon M.
alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.
Lab Invest. 2007 Jul 16; [Epub ahead of print]
PMID: 17632540 [PubMed - as supplied by publisher]
June, 2007 Selected Publications
Li HJ, Everts M, Pereboeva L, Komarova S, Idan A, Curiel DT, Herschman HR.
Adenovirus Tumor Targeting and Hepatic Untargeting by a Coxsackie/Adenovirus Receptor Ectodomain Anti-Carcinoembryonic Antigen Bispecific Adapter.
Cancer Res. 2007 Jun 1;67(11):5354-5361.
PMID: 17545616 [PubMed - as supplied by publisher]
Sarkar D, Lebedeva IV, Su ZZ, Park ES, Chatman L, Vozhilla N, Dent P, Curiel DT, Fisher PB.
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus.
Cancer Res. 2007 Jun 1;67(11):5434-42.
PMID: 17545625 [PubMed - in process]
Isayeva T, Chanda D, Kallman L, Eltoum IE, Ponnazhagan S.
Effects of Sustained Antiangiogenic Therapy in Multistage Prostate Cancer in TRAMP Model.
Cancer Res. 2007 Jun 15;67(12):5789-97.
PMID: 17575146 [PubMed - in process]
Tang L, Luo B, Patel RP, Ling Y, Zhang J, Fallon MB.
Modulation of pulmonary endothelial endothelin B receptor expression and signaling: implications for experimental hepatopulmonary syndrome.
Am J Physiol Lung Cell Mol Physiol. 2007 Jun;292(6):L1467-72. Epub 2007 Mar 2.
PMID: 17337507 [PubMed - in process]
Mitchell C, Kabolizadeh P, Ryan J, Roberts JD, Yacoub A, Curiel DT, Fisher PB, Hagan MP, Farrell NP, Grant S, Dent P.
Low dose BBR3610 toxicity in colon cancer cells is p53-independent and enhanced by inhibition of ERBB1-PI3K signaling.
Mol Pharmacol. 2007 Jun 19; [Epub ahead of print]
PMID: 17578896 [PubMed - as supplied by publisher]
Kendrick JE, Estes JM, Straughn Jr JM, Alvarez RD, Buchsbaum DJ.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers.
Gynecol Oncol. 2007 Jun 27; [Epub ahead of print]
PMID: 17602728 [PubMed - as supplied by publisher]
Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS.
Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models.
Neuro-oncol. 2007 May 23; [Epub ahead of print]
PMID: 17522331 [PubMed - as supplied by publisher]
Stoff-Khalili MA, Rivera AA, Nedeljkovic-Kurepa A, Debenedetti A, Li XL, Odaka Y, Podduturi J, Sibley DA, Siegal GP, Stoff A, Young S, Zhu ZB, Curiel DT, Mathis JM.
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast Cancer Res Treat. 2007 May 17; [Epub ahead of print]
PMID: 17508279 [PubMed - as supplied by publisher]
Reynolds AM, Xia W, Holmes MD, Hodge SJ, Danilov S, Curiel DT, Morrell NW, Reynolds PN.
Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension.
Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1182-92. Epub 2007 Feb 2.
PMID: 17277049 [PubMed - in process]
Rowe SM, Varga K, Rab A, Bebok Z, Byram K, Li Y, Sorscher EJ, Clancy JP.
Restoration of W1282X CFTR Activity by Enhanced Expression.
Am J Respir Cell Mol Biol. 2007 May 31; [Epub ahead of print]
PMID: 17541014 [PubMed - as supplied by publisher]
Sarkar D, Lebedeva IV, Gupta P, Emdad L, Sauane M, Dent P, Curiel DT, Fisher PB.
Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?
Expert Opin Biol Ther. 2007 May;7(5):577-86. Review.
PMID: 17477796 [PubMed - indexed for MEDLINE]
Tsuruta Y, Pereboeva L, Glasgow JN, Rein DT, Kawakami Y, Alvarez RD, Rocconi RP, Siegal GP, Dent P, Fisher PB, Curiel DT.
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.
Clin Cancer Res. 2007 May 1;13(9):2777-83.
PMID: 17473211 [PubMed - indexed for MEDLINE]
March, 2008 Research Grant Awards
CRAIG A ELMETS
DEPARTMENT: DERMATOLOGY
DIVISION: DERMATOLOGY
M06-890
ABBOTT LABORATORIES
New
$317,600 12/13/2007 - 6/12/2010
LAWRENCE J DELUCAS
DEPARTMENT: DEPT OF OPTOMETRY
DIVISION: DEPARTMENT OF OPTOMETRY
UCB Work Order
UAB RESEARCH FOUNDATION
Amendment/Modification
$74,750 10/1/2007 - 7/4/2008
LARISA PEREBOEVA
DEPARTMENT: PATHOLOGY CHAIR OFFICE
DIVISION: MOLECULAR & CELLULAR PATHOLOGY
Design of Targeted Cell Vehicles to Ovarian Carcinoma
NIH - NATIONAL CANCER INSTITUTE
Revised Award
$34,920 1/1/2008 - 12/31/2008
IGOR DMITRIEV
DEPARTMENT: SURGERY
DIVISION: SURG-GENERAL SURGERY
Design of Targeted Native Tropism-Ablated Adenovirus
NIH - NATIONAL CANCER INSTITUTE
Revised Award
$29,100 1/1/2008 - 12/31/2008
PAUL A GOEPFERT
DEPARTMENT: DEPARTMENT OF MEDICINE CHAIR OFFICE
DIVISION: MED - INFECTIOUS DISEASES
40% Transition Costs for Site Year 1
FRED HUTCHINSON CANCER RESEARCH CENTER
Amendment/Modification
$194,122 12/1/2007 - 5/31/2008
MITCHELL OLMAN
DEPARTMENT: DEPARTMENT OF MEDICINE CHAIR OFFICE
DIVISION: MED - PULMONARY/ALLERGY/CRITICAL CARE
Clinical Study Addendum-IPF Network
DUKE UNIVERSITY
New
$15,766 2/1/2007 - 1/31/2010
LAWRENCE J DELUCAS
DEPARTMENT: DEPT OF OPTOMETRY CHAIR'S OFFICE
DIVISION: DEPARTMENT OF OPTOMETRY
UCB Work Order
UAB RESEARCH FOUNDATION
Amendment/Modification
$23,961 10/29/2007 - 4/28/2008
ANUPAM AGARWAL
DEPARTMENT: DEPARTMENT OF MEDICINE CHAIR OFFICE
DIVISION: MED - NEPHROLOGY
Confidential Title
AMGEN, INC.
New
$3,300 3/17/2008 - 9/17/2008
SADIS MATALON
DEPARTMENT: ANESTHESIOLOGY CHAIR OFFICE
DIVISION: ANESTHESIOLOGY CHAIR OFFICE
ASRC 955
SEPRACOR, INC.
New
$174,184 3/7/2008 - 3/6/2009
February, 2008 Research Grant Awards
GRAEME B BOLGER
DEPARTMENT: DEPARTMENT OF MEDICINE
DIVISION: MED - HEMATOLOGY & ONCOLOGY
C0328T07
JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH & DEVELOPMENT, LLC
Amendment/Modification
$900 4/6/2007 - 3/31/2009
MICHAEL B FALLON
DEPARTMENT: DEPARTMENT OF MEDICINE
DIVISION: MED - GASTROENTEROLOGY
GI-5005-02
GLOBEIMMUNE, INC.
New
$207,596 1/11/2008 - 1/10/2013
PAUL A GOEPFERT
DEPARTMENT: DEPARTMENT OF MEDICINE
DIVISION: MED - INFECTIOUS DISEASES
40% Transition Costs for Site Year 1
FRED HUTCHINSON CANCER RESEARCH CENTER
New
$254,503 6/1/2007 - 11/30/2007
JOHN D MOUNTZ
DEPARTMENT: DEPARTMENT OF MEDICINE
DIVISION: MED - IMMUNOLOGY/RHEUMATOLOGY
Disruption of Autoreactive Germinal Centers as a Novel Therapy for Lupus
ALLIANCE FOR LUPUS RESEARCH
New
$500,000 2/1/2008 - 1/31/2010
DANNY R WELCH
DEPARTMENT: PATHOLOGY
DIVISION: MOLECULAR & CELLULAR PATHOLOGY
Confidential Title
CHEMOKINE THERAPEUTICS CORPORATION
New
$48,010 1/22/2008 - 7/21/2008
LAWRENCE J DELUCAS
DEPARTMENT: DEPT OF OPTOMETRY
DIVISION: DEPARTMENT OF OPTOMETRY
SIC System Development
UAB RESEARCH FOUNDATION
Amendment/Modification
$30,000 12/15/2006 - 12/14/2008
January, 2008 Research Grant Awards
GENE P SIEGAL, ANATOMIC PATHOLOGY
Confidential Title
VIVO BIOSCIENCES, INC.
New
$35,000 9/1/2007 - 8/31/2008
SADIS MATALON, ANESTHESIOLOGY
Regulation of Epithelial Sodium Channels by cGMP
UNIVERSITY OF TEXAS
New
$48,342 6/1/2007 - 1/31/2008
JOHN D MOUNTZ, MED - IMMUNOLOGY/RHEUMATOLOGY
Determinants of Human Longevity and Healthy Aging: Gene Expression and Glucose Metabolism in Aging T-Lymphocytes
TULANE UNIVERSITY
New
$83,666 9/15/2007 - 6/30/2008
DAVID GEORGE STANDAERT, NEUROLOGY
Cholinergic-Neuron Specific Inactivation of the Dyt1 Gene in Mice
BACHMANN-STRAUSS DYSTIONIA AND PARKINSON FOUNDATION, INC.
New
$50,000 1/1/2008 - 12/30/2008
JAY M MCDONALD, PATHOLOGY
Confidential Title
MERCK & COMPANY, INC.
New
$10,000 2/21/2008 - 6/20/2008
DAVID GEORGE STANDAERT, NEUROLOGY
APDA Advanced Center for Parkinson Disease Research at UAB
AMERICAN PARKINSON DISEASE ASSOCIATION
Supplement
$10,000 9/1/2007 - 8/31/2008
December, 2007 Research Grant Awards
KIRBY I BLAND, SURG-GENERAL SURGERY
SPORE in Breast Cancer
NIH - NATIONAL CANCER INSTITUTE
Competing Continuation
$11,553,815 9/25/2007 - 8/31/2012
GRAEME B BOLGER, HEMATOLOGY & ONCOLOGY
494F01 UAB 0732
ZYMOGENETICS, INC.
New
$93,805 8/16/2007 - 8/15/2012
GRAEME B BOLGER, HEMATOLOGY & ONCOLOGY
2006-005766-39 UAB 0738
CENTOCOR, INC.
New
$83,227 11/6/2007 - 3/31/2009
DAVID T CURIEL, MED - DIV OF HUMAN GENE THERAPY
Enhanced CRAd for Pancreatic Cancer
UNIVERSITY OF MINNESOTA
New
$21,875 9/1/2007 - 8/31/2008
DAVID T CURIEL, MED - DIV OF HUMAN GENE THERAPY
Characterization of Onoclytic Adenovirus deleted Core protein V Gene regulated by novel distinct pathways in
Breast Cancer Model
SUSAN G. KOMEN BREAST CANCER FOUNDATION
New
$135,000 12/1/2007 - 11/30/2010
MICHAEL B FALLON, MED - GASTROENTEROLOGY
debv-vap/evb-301
DEBIOVISION INC.
Amendment/Modification
$5,000 12/10/2006 - 08/20/2008
MICHAEL B FALLON, MED - GASTROENTEROLOGY
debv-vap/evb-301
DEBIOVISION INC.
Amendment/Modification
$57,000 8/21/2006 - 8/20/2008
JOHN D MOUNTZ, MED - IMMUNOLOGY/RHEUMATOLOGY
Confidential Title
VECTORLOGICS, INC.
New
$33,000 9/15/2007 - 3/14/2008
EDWARD E PARTRIDGE, OB/GYN - GYN ONCOLOGY
Morehouse School of Medicine/Tuskegee University/Univ. of Alabama Ca.CTr.Partnership
NIH - NATIONAL CANCER INSTITUTE
Competing Continuation
$4,169,470 9/30/2007 - 8/31/2011
HUANG-GE ZHANG, MED - IMMUNOLOGY/RHEUMATOLOGY
Breast tumor exosomal Jak3BP blocks myeloid cell differentiation
SUSAN G. KOMEN BREAST CANCER FOUNDATION
New
$300,000 12/1/2007 - 11/30/2010
November, 2007 Research Grant Awards
LAWRENCE J DELUCAS, DEPT OF OPTOMETRY
Graduate Research Scholars Program (GRP)
NSF - NATIONAL SCIENCE FOUNDATION / EPSCOR / UNIVERSITY OF ALABAMA
Amendment/Modification
$25,000 10/1/2007 - 9/30/2008
DANNY R WELCH, PATHOLOGY
NFCR Center for Metastasis Research
NATIONAL FOUNDATION FOR CANCER RESEARCH
Amendment/Modification
$150,000 10/1/2007 - 9/30/2008
JEFFREY A ENGLER, BIOCHEM & MOLECULAR GENETICS
Ronald E McNair Post-Baccalaureate Achievement Program
DOED - DEPARTMENT OF EDUCATION
New
$1,125,000 10/1/2007 - 9/30/2012
HONGJU WU, OBSTETRICS & GYNECOLOGY
Enhancing Islet Graft Survial by TAT-siRNA - Tissue Factor/MCP-1
JUVENILE DIABETES RESEARCH FOUNDATION INTERNATIONAL
New
$110,000 9/1/2007 - 8/31/2008
THERESA V STRONG, DEPARTMENT OF MEDICINE
A High Resolution Comparative Analysis of Early Onset Breast Cancer by Race
NIH - NATIONAL CANCER INSTITUTE
New
$59,749 5/1/2007 - 4/30/2009
EDWARD E PARTRIDGE, OBSTETRICS & GYNECOLOGY
Deep South Network for Cancer Control
NIH - NATIONAL CANCER INSTITUTE
Revised Award
$200,000 4/18/2007 - 3/31/2008
EDWARD E PARTRIDGE, OBSTETRICS & GYNECOLOGY
Comprehensive Cancer Center Core Support Grant
NIH - NATIONAL CANCER INSTITUTE
Supplement
$67,828 5/1/2007 - 3/31/2008
October, 2007 Research Grant Awards
David Curiel (Human Gene Therapy)
Capsid-Incorporation of HIV Antigens as a Novel Adenovirus HIV Vaccine Approach
NIAID $388,848 9/1/2007-8/31/2009
Zdenek Hel (Pathology)
Dysregulation of IgA Responses in HIV-1 Infected Individuals
NIAID $2,417,125 8/15/2007-7/31/2012
Richard Whitley
Confidential Title
Intelligent MD $5,075 8/1/2007- 12/31/2007
September, 2007 Research Grant Awards
Eric Sorscher (Hematology-Oncology)
Research Development Program - Component II
Cystic Fibrosis Foundation $1,840,000 7/1/2007-6/30/2011
Robert Conry (Hematology-Oncology)
Confidential Title
Schering-Plough Research Institute $43,035 8/20/2007-8/19/2014
Huang-Ge Zhang (Immunology-Rheumatology)
Curcumin Reverses Tumor Exosomes-Mediated Immunosuppression
National Center for Complementary & Alternative Medicine $1,450,000 9/30/2007-9/29/2011
Sadis Matalon
Adaptation of Influenze Inhibition Assays for High-Throughput Screening
NIH/ SRI $20,000 9/1/2007-8/31/2008
Casey Morrow
Molecular Analysis of HIV-1 Reverse Transcription
NIAID $54,477 2/1/2007-1/31/2008
Edward Partridge
TWC-UAB Cancer Seminars
The Wellness Community $2,500 4/1/2007-3/31/2008
August, 2007 Research Grant Awards
Kirby Bland (Surgery)
Research Training Program in Surgical Oncology
NCI $1,682,368 7/1/2007-6/30/2012
Ruiwen Zhang (Pharmacology & Toxicology)
Dietary Chemopreventive Components/Oncogene Interaction and Cancer
NCI $1,377,500 8/1/2007-5/31/2012
Meredith Preuss (Human Gene Therapy)
Confidential Title
Acetelion Pharmaceuticals $75,000 7/1/2007-6/30/2008
Sadis Matalon (Anesthesiology)
Confidential Title
Talecris Biotherapeutics Inc $48,000 5/1/2007-4/30/2008
John Mountz (Immunology-Rheumatology)
Development of Shielded Adenovirus Vector as a Vaccine Strategy for Anthrax
NIH/ SBIR/ VectorLogics Inc $43,000 5/30/2007-10/30/2007
Christopher Klug
Mechanism of inv(16) Mediated Leukomogenesis
NIH/ Vanderbilt University $86,359 5/1/2007-4/30/2008
July, 2007 Research Grant Awards
John Mountz
Novel IL-17 Induced Germinal Centers and Arthritis-Inducing Autoantibodies
American College of Rheumatology $400,000, 7/1/2007-6/30/2009
Eric Sorscher
New Reagents for Understanding and Overcoming the Delta-F508 Mutation
Cystic Fibrosis Foundation $410,400, 9/1/2007-8/31/2008
Danny Welch
Molecular Regulation of Breast Cancer Metastasis
NCI $148,875 5/1/2007-4/30/2009
Michael Fallon (Gastroenterology)
Confidential Title
Valeant Pharmaceuticals International/ PPD Development LP $423,825 6/11/2007-6/10/2010
Robert Conry
Confidential Title
Schering Plough Corp $133,150 11/19/2004-11/18/2009
George Gillespie/ Candace Gladson/ Kevin Cassady/ Donald Buchsbaum/ Lawrence Lamb/ Cheryl Palmer/ Louis Nabors/ Sreelatha Meleth
Molecular Therapeutics for Anaplastic Gliomas
NCI $1,073,000 6/1/2007-5/31/2008
Edward Partridge
Confidential Title
The Wellness Community $2,000 4/1/2007-3/31/2008
Graeme Bolger
Confidential Title
Johnson & Johnson Pharmaceutical Research & Development/ Centocor Research & Development Inc $1,080 4/6/2007-3/31/2009
Anupam Agarwal (Nephrology)
Role of HO-1 in the Pathogenesis of Lupus Nephritis
National Kidney Foundation $80,000 7/1/2007-6/30/2009
David Curiel (Human Gene Therapy)
Monitoring of Advanced Virotherapy for Ovarian Cancer
NCI $1,374,422 7/5/2007-5/31/2008
June, 2007 Research Grant Awards
Ronald Alvarez (Obstetrics & Gynecology)
Infectivity Enhanced Virotherapy for Ovarian Cancer
NCI $551,000 5/1/2007-4/30/2008
Graeme Bolger (Hematology-Oncology)
Confidential Title
Centocor Research & Development Inc $66,526 4/6/2007-3/31/2009
Michael Fallon (Gastroenterology)
Confidential Title
Wyeth Pharmaceuticals Inc $166,334 5/8/2007-5/7/2010
Joanne Douglas
Armed Replicating Ad for Breast Cancer Bone Metastasis
NCI $39,746 2/1/2007-12/31/2007
Jay McDonald (Pathology)
Confidential Title Merck & Co Inc
$6,000 6/29/2007-6/28/2008
Jay McDonald (Pathology)
Comprehensive Training Grant in Bone Biology and Disease
NIAMSD $1,323,892 5/1/2007- 4/30/2012
Michael Fallon (Gastroenterology)
Confidential Title
Human Genome Sciences Inc/ Duke University $156,880 3/1/2007-3/1/2011
Eric Sorscher/ Kevin Kirk/ David Bedwell/ John Clancy/ Steven Rowe/ Gang Liu (Hematology-Oncology)
UAB CF Research and Translation Core Center
NIDDKD $3,881,050 5/1/2007-4/30/2012
Ronald Alvarez (Obstetrics & Gynecology)
Agreement for Ronald Alvarez MD to serve Chair or Co-chair of the Protocol Chairman's Advisory Committee, COG
NIH/Gynecologic Oncology Group $13,600 4/1/2007-3/31/2008
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