MULTIDISCIPLINARY
GASTROINTESTINAL ONCOLOGY CENTER
 
 


CLINICAL TRIALS

Patients at the Multidisciplinary Gastrointestinal Oncology Center have access to many clinical trials conducted by the University of Alabama Comprehensive Cancer Center.

The following clinical trials may be available to Multidisciplinary Gastrointestinal Oncology Center patients.

This list changes frequently as new studies open and old ones close.

Disease
Protocol
Description
Anal Cancer

RT + 5-FU + Mito-C vs. RT + 5-FU + CDDP

 

Bile Duct Cancer

Phase II Rebeccamycin

 

Colon/Rectal Cancer

Phase II study of oral Xeloda in combination with intravenous Irinotecan

 

Colon/Rectal Cancer
UAB 0237

Phase II multicenter study of Erbitux™ (Cetuximab) in patients with metastatic colorectal carcinoma


Colon/Rectal Cancer

Phase II study safety and immunogenicity of ALVAC-CEA/B7.1 vaccine

 

Colon/Rectal Cancer
UAB 0249

A feasibility study of Oxaliplatin in combination with an infusional or weekly bolus 5-FU/LV or Capecitabine as first line treatment of patients with advanced colorectal cancer

 

Colon/Rectal Cancer
ECOG N9841

Randomized Phase II equivalence trial of Irinotecan vs. Oxaliplatin in combination with an infusional or weekly bolus 5-FU/LV or Capecitabine as first line treatment of patients with advanced colorectal cancer

 

Colon/Rectal Cancer

Phase IIB evaluation of Cyclooxygenase-2 activity in surgically resected primary colorectal adenomas and carcinomas after 7 days pretreatment with Celecoxib

 

Esophageal Cancer

A Phase II study of Irinotecan and Taxotere with concurrent radiotherapy as a preoperative treatment in resectable esophageal cancer


Gallbladder Cancer

Phase II Rebeccamycin
Liver Cancer

A Phase I/II open label study of T138057-sodium in patients with advanced, surgically unresectable hepatocellular carcinoma

 

Liver Cancer

Phase II Rebeccamycin

 

Pancreatic Cancer
UAB 0105

Phase III PN-401 with High Dose 5FU vs. Gemcitabine

 

Pancreatic Cancer Phase I/II open label study of Capecitabine with concurrent radiotherapy
Pancreatic Cancer
UAB 0243

Randomized, placebo-controlled, double blind Phase II study of Gemcitabine + Ly293111 compared to Gemcitabine + placebo in patients with locally advanced or metastatic pancreatic cancer

 

All cancers may be elligible

Phase I DX-8951f in patients with liver dysfunction

 

All cancers may be elligible

Phase I DX-891f in patients with renal dysfunction