CURRENTLY IN PRESS

·    Eppolito AK, Bachus SE, McDonald CG, Meador-Woodruff JH, and Smith RF:  Late Emerging Effects of Prenatal and Early Postnatal Nicotine Exposure on the Cholinergic System and Anxiety-Like Behavior.  Neurotoxicology and Teratology.  In press.

·    Kristiansen LV, Patel SA, Haroutunian V, and Meador-Woodruff JH:  Expression of the NR2B-NMDA Receptor Subunit and Its Tbr-1/CINAP Regulatory Proteins in Postmortem Brain Suggest Altered Receptor Processing in Schizophrenia.   Synapse.  In press.

·    Bauer D, Haroutunian V, Meador-Woodruff JH, and McCullumsmith RE:  Abnormal Glycosylation of EAAT1 and EAAT2 in Prefrontal Cortex of Elderly Patients with Schizophrenia.  Schizophrenia Research.  In press.
PUBLISHED

  • Uezato A, Meador-Woodruff JH, and McCullumsmith RE:  Vesicular Glutamate Transporter mRNA Expression in Medial Temporal Lobe in Major Depressive Disorder, Bipolar Disorder, and Schizophrenia.  Bipolar Disorder. 11:  711-725, 2009.

  • Funk AJ, Rumbaugh G, Haroutunian V, McCullumsmith RE, and Meador-Woodruff JH:  Decreased Expression of NMDA Receptor Associated Proteins in Frontal Cortex of Elderly Patients with Schizophrenia.  NeuroReport. 20: 1019-1022, 2009.

  • Kristiansen LV, Cowell RM, Biscaia M, McCullumsmith RE, and Meador-Woodruff JH:  Alterations of Neurotransmitter Receptors in Schizophrenia:  Evidence From Postmortem Studies.  In Javitt DC, Kantrowitz J (editors): Handbook of Neurochemistry and Molecular Neurobiology:  Schizophrenia (3rd edition).  New York:  Springer Publishers, pp. 443-492, 2009.

  • Bauer D, Haroutunian V, McCullumsmith RE, and Meador-Woodruff JH: Expression of Four Housekeeping Proteins in Elderly Patients With Schizophrenia.  Journal of Neural Transmission. 116: 487-491, 2009.

  • Cowell RM, Talati P, Blake KR, Meador-Woodruff JH, and Russell JW: Identification of Novel Targets for PGC-1α and Histone Deacetlyase Inhibitors in Neuroblastoma Cells.  Biochemical and Biophysical Research Communications. 379:  578-582, 2009.

  • Kristiansen LV, Bannon MJ, and Meador-Woodruff JH:  Expression of Transcripts for Myelin Related Genes in Postmortem Brain from Cocaine Abusers. Neurochemical Research. 34: 46-54, 2009.

  • Baker DA, Madayag A, Kristiansen LV, Meador-Woodruff JH, Haroutunian V, and Ilangoven R:  Contribution of Cystine-Glutamate Antiporters to the Psychotomimetic Effects of Phencyclidine.  Neuropsychopharmacology.  33: 1760-1772, 2008.

  • Bauer D, Gupta D, Haroutunian V, Meador-Woodruff JH, and McCullumsmith RE:  Abnormal Expression of Glutamate Transporter and Transporter Interacting Molecules in Prefrontal Cortex in Elderly Patients with Schizophrenia. Schizophrenia Research. 104: 108-120, 2008.

  • Steffek AE, McCullumsmith RE, Haroutunian V, and Meador-Woodruff JH:   Cortical Expression of Glial Fibrillary Acidic Protein and Glutamine Synthetase is decreased in Schizophrenia.  Schizophrenia Research. 103: 71-82, 2008.

  • Sodhi M, Wood KH, and Meador-Woodruff JH: The Role of Glutamate in Schizophrenia: Integrating Excitatory Avenues for Research. Expert Review of Neurotherapeutics.  8: 1389-1406, 2008.

  • Beneyto M and Meador-Woodruff JH: Lamina-Specific Abnormalities of NMDA Receptor Associated Protein Transcripts in the Prefrontal Cortex in Schizophrenia and Bipolar Disorder. Neuropsychopharmacology.  33:  2175-2186, 2008.

  • Oni-Orisan A, Kristiansen LV, Haroutunian V, Meador-Woodruff JH, and McCullumsmith RE:  Altered Vesicular Glutamate Transporter Expression in the Anterior Cingulate Cortex in Schizophrenia.  Biological Psychiatry. 63:  766-775, 2008.

  • Bauer D, McCullumsmith RE, and Meador-Woodruff JH:  A Role for Glutamate Receptors, Transporters, and Interacting Proteins in Cortical Dysfunction in Schizophrenia.  In O’Donnell P (editor):  Cortical Deficits in Schizophrenia:  From genes to Function.  New York:  Springer Publishers, pp.113-147, 2008.

  • Beneyto M, Kristiansen LV, Oni-Orisan A, McCullumsmith RE, and Meador-Woodruff JH:  Abnormal Glutamate Receptor Expression in the Medial Temporal Lobe in Schizophrenia and Mood Disorders.  Neuropsychopharmacology. 32:  1888-1902, 2007.

  • Kristiansen LV, Huerta I, Beneyto M, and Meador-Woodruff JH:  NMDA Receptors and Schizophrenia.  Current Opinion in Pharmacology. 1:48-55, 2007.

  • McCullumsmith RE, Kristiansen LV, Beneyto M, Scarr E, Dean B, and Meador-Woodruff JH:  Decreased NR1, NR2A, and SAP102 Transcript Expression in the Hippocampus in Bipolar Disorder.  Brain Research. 1127: 108-118, 2007.

  • McCullumsmith RE, Gupta D, Beneyto M, Kreger E, Haroutunian V, Davis KL, Meador-Woodruff JH:  Expression of Transcripts for Myelination-Related Genes in the Anterior Cingulate Cortex in Schizophrenia.  Schizophrenia Research.  90:  15-27, 2007.

  • Kristiansen LV, Beneyto M, Haroutunian V, Meador-Woodruff JH:  Changes in NMDA receptor subunits and interacting PSD proteins in dorsolateral prefrontal cortex and anterior cingulate cortex indicate abnormal regional expression in schizophrenia. Molecular Psychiatry. 11(8):737-747, 2006

  • Beneyto M and Meador-Woodruff JH:  Lamina-Specific Abnormalities of AMPA Receptor Trafficking and Signaling Molecule Transcripts in the Prefrontal Cortex in Schizophrenia.  Synapse. 60:  585-598, 2006.

  • Baracskay KL, Haroutunian V, Meador-Woodruff JH:  Dopamine Receptor Signaling Molecules are Altered in Elderly Schizophrenic Cortex.  Synapse. 60:  271-279, 2006.

  • Wolf TL, Kotun J, and Meador-Woodruff JH:  Plasma Copper, Iron, Ceruloplasmin and Ferroxidase Activity in Schizophrenia.  Schizophrenia Research. 86:  167-171, 2006.

  • Clinton SM, Haroutunian V, and Meador-Woodruff JH:  Up-Regulation of NMDA Receptor Subunit and Post-Synaptic Density Protein Expression in the Thalamus of Elderly Patients with Schizophrenia.  Journal of Neurochemistry. 98:  1114-1125, 2006.

  • Steffek AE, Haroutunian V, and Meador-Woodruff JH: Serine Racemase Protein Expression in Cortex and Hippocampus in Schizophrenia. Neuroreport. 17: 1181-1185, 2006.

  • Beneyto M, Kristiansen LV, McCullumsmith RE, and Meador-Woodruff JH: Glutamatergic Mechanisms in Schizophrenia: Current Concepts. Current Psychosis and Therapeutic Reports. 4(1): 27-33 2006.

  • Huerta I, McCullumsmith RE, Haroutunian V, Davis KL, Gimenez-Amaya JM, Meador-Woodruff JH: Expression of Excitatory Amino Acid Transporter Interacting Protein Transcripts in the Thalamus in Schizophrenia. Synapse. 59(7): 394-402 2006

  • Dean B, Beneyto M, Meador-Woodruff JH, McCullumsmith RE and Scarr E: Autoradiography of [3H]Aspartate and Glutamate Transport in Schizophrenia (letter). Neuropsychopharmacology. 31: 687-688, 2006. Published online 10/20/05 at http://www.acnp.org/citations/NPP102005050563/default.pdf

  • Clinton SM, Ibrahim HM, Frey KA, Davis KL, Haroutunian V, and Meador-Woodruff JH: Dopaminergic Abnormalities in Select Thalamic Nuclei in Schizophrenia: Involvement of the Intracellular Signal Integrating Proteins Calcyon and Spinophilin. American Journal of Psychiatry. 162: 1859-1871, 2005.

  • Kristiansen LV and Meador-Woodruff JH: Abnormal Striatal Expression of Transcripts Encoding NMDA Interacting PSD Proteins in Schizophrenia, Bipolar Disorder and Major Depression. Schizophrenia Research. 78(1):  87-93, 2005.

  • Gupta DS, McCullumsmith RE, Beneyto M, Haroutunian V, Davis KL, and Meador-Woodruff JH: Metabotropic Glutamate Receptor Protein Expression in the Prefrontal Cortex and Striatum in Schizophrenia. Synapse. 57: 123-131, 2005.

  • Scarr E, Beneyto M, Meador-Woodruff JH, and Dean B: Cortical Glutamatergic Markers in Schizophrenia. Neuropsychopharmacology. 30: 1521-1531, 2005.

  • Bubser M, Fadel JR, Jackson LL, Meador-Woodruff JH, Jing D, Deutch AY. Dopaminergic Regulation of Orexin Neurons. European Journal of Neuroscience. 21: 2993-3001, 2005.

  • Bruneau EG, McCullumsmith RE, Haroutunian V, Davis KL, and Meador-Woodruff JH: Increased Expression of Glutaminase and Glutamine Synthetase mRNA in the Thalamus in Schizophrenia. Schizophrenia Research. 75: 27-34, 2005.

  • Mueller HT and Meador-Woodruff JH: Distribution of the NMDA Receptor NR3A Subunit in the Adult Pig-Tail Macaque Brain. Journal of Neurochemical Anatomy. 29: 157-172, 2005.

  • Torrey EF, Barci BM, Webster MJ, Bartko JJ, Meador-Woodruff JH, and Knable MB:  Neurochemical Markers for Schizophrenia, Bipolar Disorder, and Major Depression in Postmortem Brains.  Biological Psychiatry. 57(3):252-60, 2005.

  • Mueller HT and Meador-Woodruff JH:  NR3A NMDA Receptor Subunit mRNA Expression in Schizophrenia, Depression and Bipolar Disorder.  Schizophrenia Research.  71:  361-370, 2004.

  • Clinton SM and Meador-Woodruff JH:  Abnormalities of the NMDA Receptor and Associated Intracellular Molecules in the Thalamus in Schizophrenia and Bipolar Disorder.  Neuropsychopharmacology.  29:  1353-1362, 2004.

  • McCullumsmith RE, Semins MJ, and Meador-Woodruff JH:  Effects of 6-cyano-7-nitroquinoxaline-2,3-dione on Nicotinic Receptor Subunit Transcript Expression in the Rat Brain.  Synapse.  52: 62-72, 2004.

  • Knable MB, Barci BM, Webster MJ, Meador-Woodruff JH, and Torrey EF:  Molecular Abnormalities of the Hippocampus in Severe Psychiatric Illness:  Postmortem Findings from the Stanley Foundation Neuropathology Consortium.  Molecular Psychiatry.  9:  609-620, 2004.

  • Mueller HT, Haroutunian V, Davis KL, and Meador-Woodruff JH:  Expression of the Ionotropic Glutamate Receptor Subunits and NMDA Receptor-Associated Intracellular Proteins in the Substantia Nigra in Schizophrenia.  Molecular Brain Research. 121:  60-69, 2004.

  • Ritter LM, Meador-Woodruff JH, Dalack GW: Neurocognitive measures of prefrontal cortical dysfunction in schizophrenia. Schizophrenia Research 68: 65-73, 2004

  • Clinton SM, Abelson S, Haroutunian V, Davis K, and Meador-Woodruff JH:  Neurofilament Subunit Protein Abnormalities in the Thalamus in Schizophrenia.  Thalamus and Related Systems.  2:  265-272, 2004.

  • Vawter MP, Evans S, Choudary P, Tomita H, Meador-Woodruff JH, Molnar M, Li J, Lopez JF, Myers R, Cox D, Watson SJ, Akil H, Jones EG, and Bunney WE: Gender Specific Gene Expression in Postmortem Human Brain: Localization to Sex Chromosomes. Neuropsychopharmacology 2: 373-84, 2004

  • McCullumsmith RE, and Meador-Woodruff JH:  Expression of Transcripts for the Vesicular Glutamate Transporters in the Human Medial Temporal Lobe.  Annals of the New York Academy of Sciences.  1003:  438-442, 2003.

  • Mueller HT and Meador-Woodruff JH:  Expression of the NR3A Subunit of the NMDA Receptor in Human Fetal Brain.  Annals of the New York Academy of Sciences.  1003:  448-451, 2003.

  • Beneyto M and Meador-Woodruff JH: AMPA and NMDA Associated Postsynaptic Protein Expression in Human Dorsolateral Prefrontal Cortex.  Annals of the New York Academy of Sciences.  1003:  352-355, 2003.

  • Davidkova G, McCullumsmith RE, and Meador-Woodruff JH:  Expression of ARHGEF11 mRNA in Schizophrenic Thalamus.  Annals of the New York Academy of Sciences. 1003:  375-377, 2003.

  • Oakman SA and Meador-Woodruff JH:  Calcyon Transcript Expression in Macaque Brain.  Journal of Comparative Neurology. 468:  264-276, 2004.

  • Vawter MP, Evans S, Choudary P, Tomita H, Meador-Woodruff JH, Molnar M, Li J, Lopez JF, Myers R, Cox D, Watson SJ, Akil H, Jones EG, and Bunney WE:  Gender-Specific Gene Expression in Post-Mortem Human Brain:  Localization to Sex Chromosomes.  Neuropsychopharmacology.  29: 373-384, 2004.   Online version published 9/22/03 at http://www.acnp.org/citations/NPP09220302487/

  • Beneyto M and Meador-Woodruff JH:  Expression of Transcripts Encoding AMPA Receptor Subunits and Associated Postsynaptic Proteins in the Macaque Brain.  Journal of Comparative Neurology.  468:  530-554, 2004.

  • Clinton SM and Meador-Woodruff JH:  Thalamic Dysfunction in Schizophrenia:  Neurochemical, Neuropathological, and In Vivo Imaging Abnormalities.  Schizophrenia Research.  69:  237-253, 2004.

  • McCullumsmith RE, Stincic TL, Agrawal SM, and Meador-Woodruff JH:  Differential Effects of Antipsychotics on Haloperidol-Induced Vacuous Chewing Movements and Subcortical Gene Expression in the Rat.  European Journal of Pharmacology.  477:  101-112, 2003.

  • McCullumsmith RE, Clinton SM, and Meador-Woodruff JH:  Schizophrenia as a Disorder of Neuroplasticity.  In Smythies J (editor):  Disorders of Synaptic Plasticity, a volume of International Review of Neurobiology, Volume 59.  San Diego:  Academic Press, 2004, pp. 19-45.

  • Evans SJ, Choudary PV, Vawter MP, Li J, Meador-Woodruff JH, Lopez JF, Burke SM, Thompson RC, Myers RM, Jones EG, Bunney WE, Watson SJ, and Akil H:  DNA Microarray Analysis of Functionally Discrete Human Brain Regions Reveals Divergent Transcriptional Profiles.  Neurobiology of Disease.   14:  240-250, 2003.

  • Meador-Woodruff JH, Clinton SM, Beneyto M, and McCullumsmith RE:  Molecular Abnormalities of the Glutamate Synapse in the Thalamus in Schizophrenia.  Annals of the New York Academy of Sciences.  1003:  75-93, 2003.

  • Meador-Woodruff JH:  ACNP Website Update.  ACNP Bulletin.  9 (2):  1-2, April 2003.

  • Ritter LM, Meador-Woodruff JH, and Dalack GW:  Neurocognitive Measures of Frontal Cortical Dysfunction in Schizophrenia.  Schizophrenia Research.  68:  65-73, 2004.

  • Clinton SM, Haroutunian V, Davis KL, and Meador-Woodruff JH:  Altered Transcript Expression of NMDA Receptor-Associated Postsynaptic Proteins in the Thalamus of Subjects with  Schizophrenia.   American Journal of Psychiatry.  160:  1100-1109, 2003.

  • Meador-Woodruff JH:  Update on the ACNP Website.  ACNP Bulletin.  8 (3):  5, August 2002.

  • Ritter LM, Vazquez DM, and Meador-Woodruff JH:  Ontogeny of Ionotropic Glutamate Receptor Subunit Expression in the Rat Hippocampus.  Developmental Brain Research.  139:  227-236, 2002.

  • Lopez JF, Neal CR, and Meador-Woodruff JH:  Methods of Postmortem Investigation in Human Brain.  In Charney DS and Nestler EJ (editors):  Neurobiology of Mental Illness (2nd edition).  San Francisco:  Oxford University Press.

  • Charney DS, Barlow DH, Botteron K, Cohen JD, Goldman D, Gur RE, Lin K-M, Lopez JF, Meador-Woodruff JH, Moldin SO, Nestler EJ, Watson SJ, and Zalcman SJ:  Neuroscience Research Agenda to Guide Development of a Pathophysiologically Based Classification System.  In Kupfer DJ, First MB, and Regier DA (editors):  A Research Agenda for DSM-V.  Washington, D.C.:  American Psychiatric Publishing, Inc., 2002, pp.31-83.

  • Clinton SM and Meador-Woodruff JH:  Nucleus-Specific Expression of NMDA Receptor-Associated Postsynaptic Density Proteins in Primate Thalamus.  Thalamus and Related Systems.  1:  303-316, 2002.

  • Meador-Woodruff JH:  Gene Expression in Schizophrenia.  Letter to American Journal of Psychiatry.  158:  1741, 2001.

  • McCullumsmith RE and Meador-Woodruff JH:  Striatal Excitatory Amino Acid Transporter Transcript Expression in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder.  Neuropsychopharmacology.  26:  368-375, 2002.

  • Smith RE, Haroutunian V, Davis KL, and Meador-Woodruff JH:  Vesicular Glutamate Transporter Transcript Expression in the Thalamus in Schizophrenia.  NeuroReport.  12:  1-3, 2001.

  • Smith RE, Haroutunian V, Davis KL, and Meador-Woodruff JH:  Expression of Excitatory Amino Acid Transporter Transcripts in the Thalamus in Schizophrenia.  American Journal of Psychiatry.  158:  1393-1399, 2001.

  • Ritter LM, Unis AS, and Meador-Woodruff JH:  Ontogeny of Ionotropic Glutamate Receptor Expression In Human Fetal Brain.  Developmental Brain Research.  127:  123-133, 2001.

  • Meador-Woodruff JH:  ACNP Scientific Website Update.  ACNP Bulletin.  7 (1):  14, January 2001.

  • Meador-Woodruff JH:  ACNP Scientific Website Update.  ACNP Bulletin.  6 (4): 13, October 2000.

  • Meador-Woodruff JH and Kleinman JE:  Neurochemistry of Schizophrenia:  Glutamatergic Abnormalities.  In Charney D, Coyle JT, Davis K, and Nemeroff C (editors):  Neuropsychopharmacology, The Fifth Generation of Progress.  Philadelphia: Lippincott, Williams, and Wilkins, 2002,  pp. 717-728.

  • Meador-Woodruff JH, Hogg AJ, Smith RE:  Striatal Ionotropic Glutamate Receptor Expression in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder.  Brain Research Bulletin.  55: 631-640, 2001.

  • Meador-Woodruff JH and Lenox RH:  New Initiative:  Neuropsychopharmacology Online Rapid Publication (editorial).  Neuropsychopharmacology.  23:  221-222, 2000.

  • Meador-Woodruff JH, Davis KL, and Haroutunian V: Abnormal Kainate Receptor Expression in Prefrontal Cortex in Schizophrenia.  Neuropsychopharmacology.  24:  545-552, 2001;  online version published 8/7/00 at http://www.acnp.org/citations/Npp08080001/

  • Koeppe RA, Kilbourn MR, Taylor SF, Meador-Woodruff JH, Frey KA, and Kuhl DE:  Evaluation of Extrastriatal Specific Binding of [11C]Dihydrotetrabenazine Using Active and Inactive Enantiomers.  In Gjedde A, Hansen SB,  Knudsen GM, and Paulson OB (editors):  Physiological Imaging of the Brain with PET.  San Diego:  Academic Press, 2000,  pp. 197-203.

  • Ibrahim H, Hogg AJ, Healy DJ, Haroutunian V, Davis KL,  and Meador-Woodruff JH:  Ionotropic Glutamate Receptor Binding and Subunit mRNA Expression in Thalamic Nuclei in Schizophrenia.  American Journal of Psychiatry.  157:  1811-1823, 2000.

  • Ibrahim HM, Healy DJ, Hogg AJ, and Meador-Woodruff JH:  Nucleus-Specific Expression of Ionotropic Glutamate Receptor Subunit mRNAs and Binding Sites in Primate Thalamus.  Molecular Brain Research.  79:  1-17, 2000. 

  • Healy DJ and Meador-Woodruff:  Ionotropic Glutamate Receptor Modulation Preferentially Affects NMDA Receptor Expression in Rat Hippocampus.  Synapse.  38:  294-304, 2000.

  • Smith RE, Healy DJ, and Meador-Woodruff JH:  Differential Effects of Typical and Atypical Antipsychotics on Neurotransmitter Receptor Expression and Function.  In Bolis CL, Pani L, and Licinio J (editors):  Dopaminergic System:  Evolution from Biological to Clinical Aspects.  Baltimore:  Lippincott Williams & Wilkins,  2001, pp. 25-49.

  • Meador-Woodruff JH and Healy DJ:  Glutamate Receptor Expression in Schizophrenic Brain.  Brain Research Reviews.  31:  288-294, 2000.

  • Richardson-Burns SM, Haroutunian V, Davis KL, Watson SJ, and Meador-Woodruff JH:  Metabotropic Glutamate Receptor mRNA Expression in the Schizophrenic Thalamus.  Biological Psychiatry.  47:  22-28, 2000.

  • Healy DJ and Meador-Woodruff JH:  Ionotropic Glutamate Receptor Modulation of 5-HT6 and 5-HT7 mRNA Expression in Rat Brain.  Neuropsychopharmacology.  21:  341-351, 1999.

  • Jansson A, Goldstein M, Tinner B, Zoli M, Meador-Woodruff JH, Lew JY, Levey AI, Watson S, Agnati L, and Fuxe K:  On the Distribution Patterns of D1, D2, Tyrosine Hydroxylase and Dopamine Transporter Immunoreactivities in the Ventral Striatum of the Rat.  Neuroscience.  89:  473-489, 1999.

  • Healy DJ, and Meador-Woodruff JH:  Glutamatergic Modulation of Subcortical Motor and Limbic Circuits.  Annals of the New York Academy of Sciences.  877: 684-687, 1999.

  • Frederick JA and Meador-Woodruff JH: Effects of Clozapine and Haloperidol on 5-HT6 Receptor mRNA Levels in Rat Brain.  Schizophrenia Research. 38:  7-12, 1999.

  • Meador-Woodruff JH: Novel D2-Like Dopamine Receptors in Schizophrenic Brain.  In Gattaz WF and Hafner H (editors):  Search for the Causes of Schizophrenia:  Volume IV.  Balance of the Century.  Berlin:  Springer-Verlag, 1999, pp. 251-260.

  • Dalack GW, and Meador-Woodruff JH: Acute Feasibility and Safety of a Smoking Reduction Strategy for Smokers with Schizophrenia. Nicotine and Tobacco Research. 1:  53-57, 1999.

  • Dalack GW, Becks L, Hill E, Pomerleau O, and Meador-Woodruff JH: Nicotine Withdrawal and Psychiatric Symptoms in Cigarette Smokers with Schizophrenia.   Neuropsychopharmacology.  21:  195-202, 1999.

  • Dalack GW, Healy DJ, and Meador-Woodruff JH:  Nicotine Dependence in Schizophrenia:  Clinical Phenomena and Laboratory Findings.  American Journal of Psychiatry. 155:  1490-1501, 1998.

  • Castine MR, Meador-Woodruff JH, and Dalack GW:  The Role of Life Events in Onset and Recurrent Episodes of Schizophrenia. Journal of Psychiatric Research.  32:  283-288, 1998.

  • Diwan A, Castine M, Pomerleau C, Meador-Woodruff JH, and Dalack GW: Differential Prevalence of Cigarette Smoking in Patients with Schizophrenic vs. Mood Disorders.  Schizophrenia Research.  33:  113-118, 1998.

  • Healy DJ, Haroutunian V, Powchik P, Davidson M, Davis KL, Watson SJ, and Meador-Woodruff JH:  AMPA Receptor Binding and Subunit mRNA Expression in Prefrontal Cortex and Striatum of Elderly Schizophrenics.  Neuropsychopharmacology. 19:  278-286, 1998.

  • Dalack GW, Becks L, and Meador-Woodruff JH:  Tardive Dyskinesia, Clozapine and Treatment Response. Progress in Neuro-Psychopharmacology and Biological Psychiatry.  22:  567-573, 1998.

  • Meador-Woodruff JH, and Watson SJ:  Serotonin Transporter mRNA in Schizophrenia.  Letter to Molecular Psychiatry.  2:  446, 1997

  • Meador-Woodruff JH, Haroutunian V, Powchik P, Davidson M, Davis KL, and Watson SJ: Dopamine Receptor Transcript Expression in Striatum, Prefrontal and Occipital Cortex:    Focal Abnormalities in Orbitofrontal Cortex in Schizophrenia. Archives of General Psychiatry.  54:  1089-1095, 1997.

  • Ritter LM, and Meador-Woodruff JH: Antipsychotic Regulation of Hippocampal Dopamine Receptor  Messenger RNA Expression.  Biological Psychiatry.  42:  155-164, 1997.

  • Healy DJ, Dalack GW, and Meador-Woodruff JH:  Clozapine-Reserpine Combination for Refractory Psychosis.  Letter to Schizophrenia Research. 25:  259-260, 1997.

  • Meador-Woodruff JH:  Dopamine Receptor Transcript Localization in Human Brain.  In Watson SJ (editor):  Psychopharmacology:  The Fourth Generation Of Progress, 1998 CD-ROM edition.  Philadelphia:  Lippincott-Raven Publishers, 1998, chapter 26.

  • Watson SJ, and Meador-Woodruff JH, Guest Editors, special issue of Journal of Psychiatric Research.  31 (2): 1997.  (Strategies for Postmortem Studies in Schizophrenia Research).

  • Meador-Woodruff JH, and Watson, SJ.  Editorial (“Strategies for Postmortem Studies in Schizophrenia Research”), Journal of Psychiatric Research.  31:  157-158, 1997.

  • Healy DJ, and Meador-Woodruff JH:  Clozapine and Haloperidol Differentially Regulate AMPA and Kainate Receptor Subunit mRNA Levels in Rat Cortex and Striatum.  Molecular Brain Research. 47:  331-338, 1997.

  • Mansour A, Meador-Woodruff JH, Lopez JF, and Watson SJ:  Biochemical Anatomy:  Insights Into the Cell Biology and Pharmacology of Dopamine and Serotonin Systems in the Brain.  In  Schatzberg AF and Nemeroff CB (editors):  Textbook of Psychopharmacology (2nd Edition).  Washington, D.C.:  American Psychiatric Press, 1998, pp. 55-73.

  • Joyce JN, and Meador-Woodruff JH:  Linking the Family of D2 Receptors to Neuronal Circuits in Human Brain:  Insights into Schizophrenia. Neuropsychopharmacology.  16:  375-384, 1997.

  • Meador-Woodruff JH:  Benzimidazole and Imidazopyridine Derivatives as Dopamine D3 Receptor Antagonists for the Treatment of Psychosis.  Expert Opinion on Therapeutic Patents.  6:  673-675, 1996.

  • Little KY, Gorebig J, Carroll FI, Mapili J, and Meador-Woodruff JH:  Lack of Dopamine Receptor Agonists Effect on Striatal Dopamine Transporter Binding Sites.  Brain Research.  742:  313-316, 1996.

  • Dalack GW, and Meador-Woodruff JH:  Smoking, Smoking Withdrawal and Schizophrenia:  Case Reports and a Review of the Literature.   Schizophrenia Research.  22:133-141, 1996.

  • Damask SP, Bovenkerk KA, De la Pena G, Hoversten KM, Peters DB, Valentine AM and Meador-Woodruff JH: Differential Effects of Clozapine and Haloperidol on Dopamine Receptor mRNA Expression in Rat Striatum and Cortex.  Molecular Brain Research.  41:241-249, 1996.

  • Healy DJ, and Meador-Woodruff JH:  Dopamine Receptor Gene Expression in Hippocampus is Differentially Regulated by the NMDA Receptor Antagonist MK-801.  European Journal of Pharmacology.  306:257-264, 1996.

  • Meador-Woodruff JH, King RE, Damask SP, and Bovenkerk KA:  Differential Regulation of Hippocampal AMPA and Kainate Receptor Subunit Expression by Haloperidol and Clozapine.  Molecular Psychiatry.  1:41-53, 1996.

  • Healy DJ, Sima AAF, Tapp A, Watson SJ, and Meador-Woodruff JH:  Frequency of Neuropathology in a Brain Bank from a Long-Term, Domicilliary Population.  Journal of Psychiatric Research.  30: 45-49, 1996.

  • Healy DJ and Meador-Woodruff JH:  Differential Regulation by MK-801 of Dopamine Receptor Gene Expression in Rat Nigrostriatal and Mesocorticolimbic Systems.  Brain Research.  708:38-44, 1996.

  • Meador-Woodruff JH, Damask SP, Wang J, Haroutunian V, Davis KL, and Watson SJ:   Dopamine Receptor mRNA Expression in Human Striatum and Neocortex. Neuropsychopharmacology.  15:17-29, 1996.

  • Watson SJ and Meador-Woodruff JH:  Neocortical Abnormalities in Schizophrenia.  Archives of General Psychiatry.  52:819-820, 1995.

  • Beischlag TV, Marchese A, Meador-Woodruff JH, Damask SP, O'Dowd BF, Tyndale RF, Van Tol HHM, Seeman P, and Niznik HB:  The Human Dopamine D5 Receptor Gene:  Cloning and Characterization of the 5'-Flanking and Promoter Region.  Biochemistry.  34:5960-5970, 1995.

  • Meador-Woodruff JH, Little KY, Damask SP, and Watson SJ:   Effects of Cocaine on D3 and D4 Receptor Expression in the Human Striatum.  Biological Psychiatry.  38:263-266, 1995.

  • Meador-Woodruff JH:  Mr. Jenkins's Holy Ghost.  In Ramsdell M (editor):  My First Year as a Doctor:  Real-World Stories from America's M.D.'s.  New York:  Walker and Company, 1994, pp. 49-57.

  • Meador-Woodruff JH:  Neuroanatomy of Dopamine Receptor Gene Expression:  Potential Substrates for Neuropsychiatric Illness.  Clinical Neuropharmacology.  18:S14-S24, 1995.

  • Meador-Woodruff JH, Damask SP, and Watson SJ:  Differential Expression of Autoreceptors in the Ascending Dopamine Systems of the Human Brain.  Proceedings of the National Academy of Sciences USA.  91:8297-8301, 1994.

  • Meador-Woodruff JH, Watson SJ, and Tamminga CA:  Images in Neuroscience.  Human Brain Receptors, V: Binding and Message.  American Journal of Psychiatry.  151:804, 1994.

  • Healy DJ and Meador-Woodruff JH:  Prodynorphin-Derived Peptide Expression in Primate Cortex and Stiatum.  Neuropeptides.  27:277-284, 1994.

  • Meador-Woodruff JH:  Update on Dopamine Receptors.  Annals of Clinical Psychiatry.  6:  79-90, 1994.

  • Meador-Woodruff JH, Grandy DK, Van Tol HHM, Damask SP, Little KY, Civelli O, and Watson SJ Jr.:  Dopamine Receptor Gene Expression in the Human Medial Temporal Lobe.  Neuropsychopharmacology.  10:239-248, 1994.

  • DeQuardo JR, Tandon R, Goldman R, Meador-Woodruff JH, McGrath-Giroux M, Brunberg JA, and Kim L:  Ventricular Enlargement, Neuropsychological Status, and Premorbid Function in Schizophrenia.  Biological Psychiatry.  35:517-524, 1994.

  • Meador-Woodruff JH, Little KY, Damask SP, Mansour A, and Watson SJ:  Effects of Cocaine on Dopamine Receptor Gene Expression:  A Study in the Postmortem Human Brain.  Biological Psychiatry.  34:348-355, 1993.

  • Ramsdell CD, and Meador-Woodruff JH:  Expression of Prodynorphin-derived Peptides and mRNA in Guinea-pig Cortex.  Neuropeptides.  25:131-138, 1993.

  • Mansour A, Chalmers DT, Fox CA, Meador-Woodruff JH, and Watson SJ:  Biochemical Anatomy:  Insights Into the Cell Biology and Pharmacology of Neurotransmitter Systems in the Brain.  In Schatzberg AF and Nemeroff CB (editors):  Textbook of Psychopharmacology.  Washington, D.C.:  American Psychiatric Press, 1995, pp. 45-63.

  • Day NC, Lin H, Ueda Y, Meador-Woodruff JH, and Akil H:  Characterization of Pro-opiomelanocortin Processing in Heterologous Neuronal Cells that Express PC2 mRNA.  Neuropeptides.  24: 253-262, 1993.

  • Meador-Woodruff JH, Mansour A, Saul J, and Watson SJ:  Neuroanatomical Distribution of Dopamine Receptor mRNAs.  In Niznik HB (editor):  Dopamine Receptors and Transporters: Pharmacology, Structure, and Function.  New York:  Marcel Dekker, 1994, pp. 401-415.

  • Trujillo KA, Herman JP, Schafer MK-H, Mansour A, Meador-Woodruff JH, Watson SJ, and Akil H:  Drug Reward and Brain Circuitry:  Recent Advances and Future Directions.  In Korenman SG, and Barchas JD (editors):  Biological Basis of Substance Abuse.  New York:  Oxford University Press.  in press.

  • Meador-Woodruff JH, Mansour A, Grandy DK, Damask SP, Civelli O, and Watson SJ:  Distribution of D5 Dopamine Receptor mRNA in Rat Brain.  Neuroscience Letters.  145:  209-212, 1992.

  • Mansour A, Meng F, Meador-Woodruff JH, Taylor LP, Civelli O, and Akil H:  Site-Directed Mutagenesis of the Human Dopamine D2 Receptor.   European Journal of Pharmacology,  227: 205-214, 1992.

  • Meador-Woodruff JH, and Mansour A:  Expression of the Dopamine D2 Receptor Gene in Brain (1991 A. E. Bennett Award Paper).  Biological Psychiatry.   30:  985-1007, 1991.

  • Meador-Woodruff JH, Mansour A, Healy DJ, Kuehn R, Zhou Q-Y, Bunzow JR, Akil H, Civelli O, and Watson SJ:  Comparision of the Distributions of D1 and D2 Dopamine Receptor mRNAs in Rat Brain.   Neuropsychopharmacology.  5:  231-242, 1991.

  • Mansour A, Meador-Woodruff JH, Zhou Q-Y, Civelli O, Akil H, and Watson SJ:  A Comparison of D1 Receptor Binding and mRNA in Rat Brain Using Receptor Autoradiographic and In Situ Hybridization Techniques.  Neuroscience.  45:  359-371, 1991.

  • Meador-Wooduff JH, Mansour A, Civelli O, and Watson SJ:  Distribution of D2 Dopamine Receptor mRNA in the Primate Brain.  Progress in Neuropsychopharmacology and Biological Psychiatry.  15:  885-893, 1991.

  • Tandon R, Mazzara C, DeQuardo J, Craig KA, Meador-Woodruff JH, Goldman R, and Greden JF:  Dexamethasone Suppression Test in Schizophrenia:  Relationship to Symptomatology, Ventricular Enlargement, and Outcome.  Biological Psychiatry.  29:  953-964, 1991.

  • Goldstein DJ, and Meador-Woodruff JH:  Opiate Receptors:  Opioid Agonist-Antagonist Effects.  Pharmacotherapy.  11:  164-167, 1991.

  • Meador-Woodruff JH:   Basal Ganglia Mineralization in Schizophrenia.  Letter to Biological Psychiatry.  29:  296-297, 1991.

  • Day NC, Meador-Woodruff JH, and Akil H:  Expression and Processing of POMC in a Neuronal Cell Line.  In van Ree JM, Mulder AH, Wiegant VM, and van Wimersma Griedanus TB (editors):  New Leads in Opioid Research.  Amsterdam:  Elsevier, 1990, pp.113-115.

  • Mansour A, Meador-Woodruff JH, Camp DM, Robinson TE, Bunzow J, Van Tol H, Civelli O, Akil H, and Watson SJ:  The Effects of Nigrostriatal 6-Hydroxydopamine Lesions on Dopamine D2 Receptor mRNA and Opioid Systems.  In Quirion R, Jhamandas K, and Gianoulakis C (editors):  The International Narcotics Research Conference (INRC) '89.  New York:  Alan R. Liss, 1990, pp. 227-230.

  • Mansour A, Meador-Woodruff JH, Bunzow JR, Van Tol HHM, Civelli O, Akil H, and Watson SJ:  Localization of Dopamine D2 Receptor mRNA and D1 and D2 Receptor Binding in the Rat Brain and Pituitary:  An In Situ Hybridization-Receptor Autoradiographic Analysis.  Journal of Neuroscience.  10:  2587-2600, 1990.

  • Meador-Woodruff JH, Greden JF,  Grunhaus L, and Haskett RF:  Severity of Depression and Hypothalamic-Pituitary-Adrenal Axis Dysregulation:  Identification of Contributing Factors.  Acta Psychiatrica Scandinavica.  81:  364-371, 1990.

  • Gurguis GNM, Meador-Woodruff JH, Haskett RF, and Greden JF:  Multiplicity of Depressive Episodes:  Phenomenological and Neuroendocrine Correlates.  Biological Psychiatry.  27:  1156-1164, 1990.

  • Meador-Woodruff JH, Pellerito B, Bronstein D, Lin H-L, Ling N, and Akil H:  Differential Effects of Haloperidol on the Rat Pituitary:  Decreased Biosynthesis, Processing and Release of Anterior Lobe Proopiomelanocortin.  Neuroendocrinology.  51:  294-303, 1990.

  • Meador-Woodruff JH:  Psychiatric Side Effects of Tricyclic Antidepressants.  Hospital and Community Psychiatry.  41:  84-86, 1990.

  • Meador-Woodruff JH, Mansour A, Bunzow JR, Van Tol HHM, Watson SJ, and Civelli O:  Distribution of D2 Dopamine Receptor mRNA in Rat Brain.   Proceedings of the National Academy of Sciences USA.  86:  7625-7628, 1989.

  • Meador-Woodruff JH, Silk KR, Kronfol Z, Watson SJ, and Akil H:  γ-Melanotropin and ß-Endorphin After Dexamethasone.  Biological Psychiatry.  25:  975-976, 1989.

  • Tandon R, Silk KR, Greden JF, Goodson J, Hariharan M, Meador-Woodruff JH, and Kronfol Z: Positive and Negative Symptoms in Schizophrenia and the Dexamethasone Suppression Test.   Biological Psychiatry.  25:  788-792, 1989.

  • Meador-Woodruff JH, and Greden JF:  Effects of Psychotropic Medications on Hypothalamic-Pituitary-Adrenal Regulation.   In Brown WA (editor):  Endocrinology of Neuropsychiatric Disorders.  Neurologic Clinics.  6:  225-234, 1988. 

  • Meador-Woodruff JH, and Greden JF:  Effects of Psychotropic Medications on Hypothalamic-Pituitary-Adrenal Regulation.  In Brown WA (editor):  Endocrinology of Neuropsychiatric Disorders.   Endocrinology and Metabolism Clinics of North America.  17:  225-234, 1988. 

  • Meador-Woodruff JH, Greden JF, Grunhaus L, and Haskett RF:   Plasma Postdexamethasone Cortisol Levels in Schizoaffective Disorder.   Psychiatry Research.   26:  35-42, 1988.

  • Meador-Woodruff JH, Greden JF, Grunhaus L, and Haskett RF:  Dexamethasone Suppression Test  Status and Severity of Depression.  Biological Psychiatry.  24:  693-696, 1988.

  • Meador-Woodruff JH, Pellerito B, Vaudry H, Jégou S, Seidah NG, Watson SJ, and Akil H: Regional Processing of the N- and C-Terminal Domains of Proopiomelanocortin in Monkey Pituitary and Brain.  Neuropeptides.   11:  111-118, 1988.

  • Meador-Woodruff JH, and Majchzrak M:  Doxepin-Induced Cardiac Dysrhythmia.  Letter to  Journal of Clinical Psychopharmacology.  8:  144-145, 1988.

  • Meador-Woodruff JH, Akil M, Wisner-Carlson R, and Grunhaus L:  Behavioral and Cognitive Toxicity Related to Elevated Plasma Tricyclic Antidepressant Levels.  Journal of Clinical Psychopharmacology.  8:  28-32, 1988.

  • Meador-Woodruff JH, Haskett RF, Grunhaus L, Akil H, Watson SJ, and Greden JF: Postdexamethasone Plasma Cortisol and β-Endorphin Levels in Depression:  Relationship to Severity of Illness.  Biological Psychiatry.  22:  1137-1150, 1987.

  • Meador-Woodruff JH, Watson SJ, Murphy-Weinberg V, Jégou S, Vaudry H, Seidah NG, Rivier J, Vale W, and Akil H:  Gamma-Melanotropin Response to Ovine Corticotropin Releasing Factor in Normal Humans.  Neuropeptides.  9: 269-282, 1987.

  • Meador-Woodruff JH, Gurguis G, Grunhaus L, Haskett RF, and Greden JF:  Multiple Depressive Episodes and Plasma Postdexamethasone Cortisol Levels.  Biological Psychiatry.  22: 583-592, 1987.

  • Meador-Woodruff JH, and Greden JF:  Clinician-Researchers in Psychiatry.  Letter to  American Journal of Psychiatry.  144: 535, 1987.

  • Meador-Woodruff JH, Knobloch M, Vaudry H, Seidah NG, Watson SJ, and Akil H:  Gamma-3-MSH and -Endorphin in Monkey Pituitary. In Holaday JW, Law P-W, and Herz A (editors):  Progress in Opioid Research (National Institute on Drug Abuse Research Monograph #75).  Rockville, Maryland: U.S. Department of Health and Human Services, 1986,  pp. 307-310.

  • Meador-Woodruff JH, and Grunhaus L:  Profound Behavioral Toxicity Due to Tricyclic Antidepressants. Journal of Nervous and Mental Disease.  174: 628-630, 1986.

  • Meador-Woodruff JH, Yoshino JE, Bigbee JW, Lewis BL, and DeVries GH:  Differential Proliferative Responses of Cultured Schwann Cells to Axolemma- and Myelin-Enriched Fractions. II. Morphological Studies. Journal of Neurocytology.  14: 619-635, 1985.

  • Yoshino JE, Dinneen MP, Lewis BL, Meador-Woodruff JH, and DeVries GH:  Differential Proliferative Responses of Cultured Schwann Cells to Axolemma- and Myelin-Enriched Fractions. I. Biochemical Studies.  Journal of Cell Biology.  99: 2309-2313, 1984.

  • Meador-Woodruff JH, Lewis BL, and DeVries GH:   Cyclic AMP and Calcium as Potential Mediators of Stimulation of Cultured Schwann Cell Proliferation by Axolemma-Enriched and Myelin-Enriched Membrane Fractions.  Biochemical and Biophysical Research Communications.  122: 373-380, 1984. 

  • Topham RW, Woodruff JH, and Walker MC:  Purification and Characterization of the Intestinal Promoter of Iron (3+)-Transferrin Formation.  Biochemistry.  20: 319-324, 1981.

  • Topham RW, Woodruff JH, Neatrour GP, Calisch MP, Russo RB, and Jackson MR:  The Role of Ferroxidase-II and a Ferroxidase Inhibitor in Iron Mobilization from Tissue Stores.  Biochemical and Biophysical Research Communications.  96: 1532-1539, 1980.