Assistant Professor of Medicine

Contact Information
Zeigler Building, Room 1014
1530 3rd Avenue South
Birmingham, Alabama 35294-0006
Office Phone: (205) 934-4729
Office Fax: (205) 934-0424





Postdoc Fellowship
Vascular Biology and Hypertension Program, UAB (2001-2006)

Doctor of Philosophy
Peking University, Beijing, China (2001)

Master Degree
Xi’an Medical University, Xi’an, China (1998)



Research Interests

Estrogen Modulates Inflammatory Mediator Expression and Neutrophil Chemotaxis in Injured Arteries
Role of O-GlcNAcylation in Inflammation- Induced Vascular Injury
Role of NFkappaB Signaling in Vasoprotective Effects of Estrogen

Selected Journal Articles

Xing D, Li P, Gong K, Yang Z, Yu H, Hage FG, Oparil S, Chen YF. Endothelial Cells Overexpressing Interleukin-8 (IL8) Receptors Reduce Inflammatory and Neointimal Responses to Arterial Injury. Circulation. 2012 Feb 23. [Epub ahead of print]
PMID: 22361324

Gong K, Xing D, Li P, Aksut B, Ambalavanan N, Yang Q, Nozell SE, Oparil S, Chen YF. Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling. Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L899-907. Epub 2011 Sep 16.
PMID: 21926264

Gong K, Xing D, Li P, Hilgers RH, Hage FG, Oparil S, Chen YF. cGMP inhibits TGF-beta signaling by sequestering Smad3 with cytosolic beta2-tubulin in pulmonary artery smooth muscle cells. Mol Endocrinol. 2011 Oct;25(10):1794-803. Epub 2011 Aug 25.
PMID: 21868450

Gong K, Chen YF, Li P, Lucas JA, Hage FG, Yang Q, Nozell SE, Oparil S, Xing D. Transforming growth factor-β inhibits myocardial PPARγ expression in pressure overload-induced cardiac fibrosis and remodeling in mice.
J Hypertens. 2011 Sep;29(9):1810-9.
PMID: 21836474

Xing D, Gong K, Feng W, Nozell SE, Chen YF, Chatham JC, Oparil S. O-GlcNAc modification of NFκB p65 inhibits TNF-α-induced inflammatory mediator expression in rat aortic smooth muscle cells. PLoS One. 2011;6(8):e24021. Epub 2011 Aug 31.
PMID: 21904602


PubMed Listings

Dongqi Xing, MD, PhD