Publications Citing the HRFDCC

1. Zhou, J, Ouyang, X, Schoeb, TR, Bolisetty, S, Cui, X, Mrug, S, Yoder, BK, Johnson, MR, Szalai, AJ, Mrug, M: Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complement. Journal of the American Society of Nephrology : JASN, 23: 1161-1171, 2012.

2. Sharma, N, Malarkey, EB, Berbari, NF, O'Connor, AK, Vanden Heuvel, Mrug, M, Yoder, B, K: Proximal Tubule Proliferation is Insufficient to Induce Rapid Cyst Formation following Cilia Disruption. Journal of the American Society for Nephrology, In press, 2012.

3. Saigusa, T, Reichert, R, Guare, J, Siroky, BJ, Gooz, M, Steele, S, Fenton, RA, Bell, PD, Kolb, RJ: Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. American journal of physiology Renal physiology, 302: F801-808, 2012.

4. Pasek, RC, Berbari, NF, Lewis, WR, Kesterson, RA, Yoder, BK: Mammalian Clusterin-associated protein 1 is an evolutionarily conserved intraflagellar transport complex B member. Cilia, In Press, 2012.

5. Olteanu, D, Liu, X, Liu, W, Roper, VC, Sharma, N, Yoder, BK, Satlin, LM, Schwiebert, EM, Bevensee, MO: Increased Na+/H+ exchanger activity on the apical surface of a cilium-deficient cortical collecting duct principal cell model of polycystic kidney disease. American journal of physiology Cell physiology, 302: C1436-1451, 2012.

6. McIntyre, JC, Davis, EE, Joiner, A, Williams, CL, Tsai, IC, Jenkins, PM, McEwen, DP, Zhang, L, Escobado, J, Thomas, S, Szymanska, K, Johnson, CA, Beales, PL, Green, ED, Mullikin, JC, Sabo, A, Muzny, DM, Gibbs, RA, Attie-Bitach, T, Yoder, BK, Reed, RR, Katsanis, N, Martens, JR: Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. Nature medicine, 18: 1423-1428, 2012.

7. Flores, D, Liu, Y, Liu, W, Satlin, LM, Rohatgi, R: Flow-induced prostaglandin E2 release regulates Na and K transport in the collecting duct. American journal of physiology Renal physiology, 303: F632-638, 2012.

8. Berbari, NF, Sharma, N, Malarkey, EB, Pieczynski, JN, Boddu, R, Gaertig, J, Guay-Woodford, L, Yoder, BK: Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease. Cytoskeleton (Hoboken), 2012.

9. Williams, CL, Li, C, Kida, K, Inglis, PN, Mohan, S, Semenec, L, Bialas, NJ, Stupay, RM, Chen, N, Blacque, OE, Yoder, BK, Leroux, MR: MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis. The Journal of cell biology, 192: 1023-1041, 2011.

10. Tower-Gilchrist, C, Lee, E, Sztul, E: Endosomal trafficking of the G protein-coupled receptor somatostatin receptor 3. Biochemical and biophysical research communications, 413: 555-560, 2011.

11. Sproul, A, Steele, SL, Thai, TL, Yu, S, Klein, JD, Sands, JM, Bell, PD: N-methyl-D-aspartate receptor subunit NR3a expression and function in principal cells of the collecting duct. American journal of physiology Renal physiology, 301: F44-54, 2011.

12. Sharma, N, Kosan, ZA, Stallworth, JE, Berbari, NF, Yoder, BK: Soluble levels of cytosolic tubulin regulate ciliary length control. Molecular biology of the cell, 22: 806-816, 2011.

13. Sas, KM, Janech, MG, Favre, E, Arthur, JM, Bell, PD: Cilia movement regulates expression of the Raf-1 kinase inhibitor protein. American journal of physiology Renal physiology, 300: F1163-1170, 2011.

14. Masyukova, SV, Winkelbauer, ME, Williams, CL, Pieczynski, JN, Yoder, BK: Assessing the pathogenic potential of human Nephronophthisis disease-associated NPHP-4 missense mutations in C. elegans. Human molecular genetics, 20: 2942-2954, 2011.

15. Egorova, AD, Khedoe, PP, Goumans, MJ, Yoder, BK, Nauli, SM, ten Dijke, P, Poelmann, RE, Hierck, BP: Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition. Circulation research, 108: 1093-1101, 2011.

16. Eccleston, HB, Andringa, KK, Betancourt, AM, King, AL, Mantena, SK, Swain, TM, Tinsley, HN, Nolte, RN, Nagy, TR, Abrams, GA, Bailey, SM: Chronic exposure to a high-fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice. Antioxidants & redox signaling, 15: 447-459, 2011.

17. Berbari, NF, Kin, NW, Sharma, N, Michaud, EJ, Kesterson, RA, Yoder, BK: Mutations in Traf3ip1 reveal defects in ciliogenesis, embryonic development, and altered cell size regulation. Developmental biology, 360: 66-76, 2011.

18. Bell, PD, Fitzgibbon, W, Sas, K, Stenbit, AE, Amria, M, Houston, A, Reichert, R, Gilley, S, Siegal, GP, Bissler, J, Bilgen, M, Chou, PC, Guay-Woodford, L, Yoder, B, Haycraft, CJ, Siroky, B: Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. Journal of the American Society of Nephrology : JASN, 22: 839-848, 2011.

19. Zvereff, V, Yao, S, Ramsey, J, Mikhail, FM, Vijzelaar, R, Messiaen, L: Identification of PKHD1 multiexon deletions using multiplex ligation-dependent probe amplification and quantitative polymerase chain reaction. Genetic testing and molecular biomarkers, 14: 505-510, 2010.

20. Zhou, J, Ouyang, X, Cui, X, Schoeb, TR, Smythies, LE, Johnson, MR, Guay-Woodford, LM, Chapman, AB, Mrug, M: Renal CD14 expression correlates with the progression of cystic kidney disease. Kidney international, 78: 550-560, 2010.

21. Williams, CL, Masyukova, SV, Yoder, BK: Normal ciliogenesis requires synergy between the cystic kidney disease genes MKS-3 and NPHP-4. Journal of the American Society of Nephrology : JASN, 21: 782-793, 2010.

22. Steele, SL, Wu, Y, Kolb, RJ, Gooz, M, Haycraft, CJ, Keyser, KT, Guay-Woodford, L, Yao, H, Bell, PD: Telomerase immortalization of principal cells from mouse collecting duct. American journal of physiology Renal physiology, 299: F1507-1514, 2010.

23. Hellman, NE, Liu, Y, Merkel, E, Austin, C, Le Corre, S, Beier, DR, Sun, Z, Sharma, N, Yoder, BK, Drummond, IA: The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proceedings of the National Academy of Sciences of the United States of America, 107: 18499-18504, 2010.

24. Andringa, KK, King, AL, Eccleston, HB, Mantena, SK, Landar, A, Jhala, NC, Dickinson, DA, Squadrito, GL, Bailey, SM: Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection. American journal of physiology Gastrointestinal and liver physiology, 298: G732-745, 2010.

25. Andringa, KK, Bailey, SM: Detection of protein thiols in mitochondrial oxidative phosphorylation complexes and associated proteins. Methods in enzymology, 474: 83-108, 2010.

26. O'Connor, AK, Kesterson, RA, Yoder, BK: Generating conditional mutants to analyze ciliary functions: the use of Cre-lox technology to disrupt cilia in specific organs. Methods in cell biology, 93: 305-330, 2009.

27. Kesterson, RA, Berbari, NF, Pasek, RC, Yoder, BK: Utilization of conditional alleles to study the role of the primary cilium in obesity. Methods in cell biology, 94: 163-179, 2009.

28. Karner, CM, Chirumamilla, R, Aoki, S, Igarashi, P, Wallingford, JB, Carroll, TJ: Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis. Nature genetics, 41: 793-799, 2009.

29. Williams, CL, Winkelbauer, ME, Schafer, JC, Michaud, EJ, Yoder, BK: Functional redundancy of the B9 proteins and nephrocystins in Caenorhabditis elegans ciliogenesis. Molecular biology of the cell, 19: 2154-2168, 2008.

30. Willaredt, MA, Hasenpusch-Theil, K, Gardner, HA, Kitanovic, I, Hirschfeld-Warneken, VC, Gojak, CP, Gorgas, K, Bradford, CL, Spatz, J, Wolfl, S, Theil, T, Tucker, KL: A crucial role for primary cilia in cortical morphogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience, 28: 12887-12900, 2008.

31. Wang, D, Stockard, CR, Harkins, L, Lott, P, Salih, C, Yuan, K, Buchsbaum, D, Hashim, A, Zayzafoon, M, Hardy, RW, Hameed, O, Grizzle, W, Siegal, GP: Immunohistochemistry in the evaluation of neovascularization in tumor xenografts. Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83: 179-189, 2008.

32. Sharma, N, Berbari, NF, Yoder, BK: Ciliary dysfunction in developmental abnormalities and diseases. Current topics in developmental biology, 85: 371-427, 2008.

33. Mrug, M, Zhou, J, Woo, Y, Cui, X, Szalai, AJ, Novak, J, Churchill, GA, Guay-Woodford, LM: Overexpression of innate immune response genes in a model of recessive polycystic kidney disease. Kidney international, 73: 63-76, 2008.

34. Marose, TD, Merkel, CE, McMahon, AP, Carroll, TJ: Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state. Developmental biology, 314: 112-126, 2008.

35. Lin, M, Jackson, P, Tester, AM, Diaconu, E, Overall, CM, Blalock, JE, Pearlman, E: Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro. The American journal of pathology, 173: 144-153, 2008.

36. Lehman, JM, Michaud, EJ, Schoeb, TR, Aydin-Son, Y, Miller, M, Yoder, BK: The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men. Developmental dynamics : an official publication of the American Association of Anatomists, 237: 1960-1971, 2008.

37. Jones, C, Roper, VC, Foucher, I, Qian, D, Banizs, B, Petit, C, Yoder, BK, Chen, P: Ciliary proteins link basal body polarization to planar cell polarity regulation. Nature genetics, 40: 69-77, 2008.

38. Hovater, MB, Olteanu, D, Hanson, EL, Cheng, NL, Siroky, B, Fintha, A, Komlosi, P, Liu, W, Satlin, LM, Bell, PD, Yoder, BK, Schwiebert, EM: Loss of apical monocilia on collecting duct principal cells impairs ATP secretion across the apical cell surface and ATP-dependent and flow-induced calcium signals. Purinergic signalling, 4: 155-170, 2008.

39. Gaggar, A, Jackson, PL, Noerager, BD, O'Reilly, PJ, McQuaid, DB, Rowe, SM, Clancy, JP, Blalock, JE: A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol, 180: 5662-5669, 2008.

40. Yoder, BK: Role of primary cilia in the pathogenesis of polycystic kidney disease. Journal of the American Society of Nephrology : JASN, 18: 1381-1388, 2007.

41. Olteanu, D, Hovater, MB, Schwiebert, EM: Intraluminal autocrine purinergic signaling within cysts: implications for the progression of diseases that involve encapsulated cyst formation. American journal of physiology Renal physiology, 292: F11-14, 2007.

42. Malik, M, Bakshi, CS, McCabe, K, Catlett, SV, Shah, A, Singh, R, Jackson, PL, Gaggar, A, Metzger, DW, Melendez, JA, Blalock, JE, Sellati, TJ: Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis. J Immunol, 178: 1013-1020, 2007.

43. Davenport, JR, Watts, AJ, Roper, VC, Croyle, MJ, van Groen, T, Wyss, JM, Nagy, TR, Kesterson, RA, Yoder, BK: Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Current biology : CB, 17: 1586-1594, 2007.

44. Belmadani, S, Bernal, J, Wei, CC, Pallero, MA, Dell'italia, L, Murphy-Ullrich, JE, Berecek, KH: A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II. The American journal of pathology, 171: 777-789, 2007.

45. Banizs, B, Komlosi, P, Bevensee, MO, Schwiebert, EM, Bell, PD, Yoder, BK: Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse. American journal of physiology Cell physiology, 292: C1409-1416, 2007.

46. Siroky, BJ, Ferguson, WB, Fuson, AL, Xie, Y, Fintha, A, Komlosi, P, Yoder, BK, Schwiebert, EM, Guay-Woodford, LM, Bell, PD: Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells. American journal of physiology Renal physiology, 290: F1320-1328, 2006.