Assistant Professor of Medicine

Address: 

Shelby Bldg, Room 205
1825 University Blvd
35294-2182

Telephone: (205) 996-4477
Fax: (205) 975-4404
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
 

Education

 
Diploma, Wuhan University, China, 1979
MS, Wuhan University, China, 1982
PhD, University of Alabama at Birmingham, 1992
Post-Doctoral Training (Immunology): Cleveland Clinic Foundation, 1992-1994
Post-Doctoral Training: University of Alabama at Birmingham, 1995-1997


Research Description

 
Dr. Li's major research interest is investigation of biological effects of Fcγ Receptor polymorphisms. Elucidation of the biological functions mediated by Fcγ Receptors.
 

Selected Publications

 
Su K, Yang H, Li X, Li X, Gibson AW, Cafardi JM, Zhou T, Edberg JC, Kimberly RP. 2007. Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J Immunol. 178(5):3272-80. PMID: 17312177

 
Su K, Li X, Edberg JC, Wu J, Ferguson P, Kimberly RP. 2004. A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor expression and function. J Immunol. 172(11):7192-9. PMID: 15153544

 
Su K, Wu J, Edberg JC, Li X, Ferguson P, Cooper GS, Langefeld CD, Kimberly RP. 2004. A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus. J Immunol. 172(11):7186-91. PMID: 15153543

 
Li X, Wu J, Carter RH, Edberg JC, Su K, Cooper GS, Kimberly RP. 2003. A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum. 48(11):3242-52. PMID: 14613290

 
Xu Y, Szalai AJ, Zhou T, Zinn KR, Chaudhuri TR, Li X, Koopman WJ, Kimberly RP. 2003. Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics. J Immunol. 171(2):562-8. PMID: 12847219

 
Kimberly RP, Wu J, Gibson AW, Su K, Qin H, Li X, Edberg JC. 2002. Diversity and duplicity: human FCgamma receptors in host defense and autoimmunity. Immunol Res. 26(1-3):177-89.  PMID: 12403356

 
Wang Y, Brooks SR, Li X, Anzelon AN, Rickert RC, Carter RH. 2002. The physiologic role of CD19 cytoplasmic tyrosines. Immunity. 17(4):501-14. PMID: 12387743