Heck-2011Professor of Medicine


Faculty Office Tower, Room 858B

Email: lwh410@uab.edu



MD, Indiana University School of Medicine, 1973
Internship, Indiana University Hospitals
Residency, Indiana University Hospitals
Postdoctoral Training, Harvard Medical School

Research Interests

Dr. Heck's main interests are the etiology and treatment of rheumatoid arthritis and osteoarthritis. 

Selected Publications

Chaiamnuay S, Heck LW, Bell WC, Bastian HM. 2007. Acute granulomatous lupus pneumonitis: the first case report. Lupus. 16(3):201-4. Review. PMID: 17432106

Chaiamnuay S, Heck LW. 2005. Antineutrophil cytoplasmic antibody vasculitis associated with mycobacterium avium intracellulare infection. J Rheumatol. 32(8):1610-2. PMID: 16078343

Mazzuca SA, Brandt KD, Schauwecker DS, Katz BP, Meyer JM, Lane KA, Bradley JD, Hugenberg ST, Wolfe F, Moreland LW, Heck LW, Yocum DE, Schnitzer TJ, Sharma L, Manzi S, Oddis CV. 2005. Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis. J Rheumatol. 32(8):1540-6. PMID: 16078332

Brandt KD, Mazzuca SA, Katz BP, Lane KA, Buckwalter KA, Yocum DE, Wolfe F, Schnitzer TJ, Moreland LW, Manzi S, Bradley JD, Sharma L, Oddis CV, Hugenberg ST, Heck LW. 2005. Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial. Arthritis Rheum. 52(7):2015-25. PMID: 15986343

Mazzuca SA, Brandt KD, Katz BP, Lane KA, Bradley JD, Heck LW, Hugenberg ST, Manzi S, Moreland LW, Oddis CV, Schnitzer TJ, Sharma L, Wolfe F, Yocum DE. 2004. Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug. Arthritis Rheum. 51(6):933-40. PMID: 15593174

Moreland LW, Morgan EE, Adamson TC 3rd, Fronek Z, Calabrese LH, Cash JM, Markenson JA, Matsumoto AK, Bathon J, Matteson EL, Uramoto KM, Weyand CM, Koopman WJ, Heck LW, Strand V, Diveley JP, Carlo DJ, Nardo CJ, Richieri SP, Brostoff SW. 1998. T cell receptor peptide vaccination in rheumatoid arthritis: a placebo-controlled trial using a combination of Vbeta3, Vbeta14, and Vbeta17 peptides. Arthritis Rheum. 41(11):1919-29. PMID: 9811045

Moreland LW, Haverty TP, Wacholtz MC, Knowles RW, Bucy RP, Heck LW Jr, Koopman WJ. 1998. Nondepleting humanized anti-CD4 monoclonal antibody in patients with refractory rheumatoid arthritis. J Rheumatol. 25(2):221-8. PMID: 9489810

Niemann KK, Bartlett JD, Heck LW Jr, McCollum CJ. 1997. Nodular scleritis: case report involving immunosuppressive therapy. J Am Optom Assoc. 68(12):782-7. PMID: 9635385

Moreland LW, Heck LW Jr, Koopman WJ. 1997. Biologic agents for treating rheumatoid arthritis. Concepts and progress. Arthritis Rheum. 40(3):397-409. Review.  PMID: 9082924

Moreland LW, Margolies G, Heck LW Jr, Saway A, Blosch C, Hanna R, Koopman WJ. 1996. Recombinant soluble tumor necrosis factor receptor (p80) fusion protein: toxicity and dose finding trial in refractory rheumatoid arthritis. J Rheumatol. 23(11):1849-55. PMID: 8923355

Moreland LW, Heck LW Jr, Koopman WJ, Saway PA, Adamson TC, Fronek Z, O'Connor RD, Morgan EE, Diveley JP, Richieri SP, Carlo DJ, Brostoff SW. 1996. V beta 17 T cell receptor peptide vaccination in rheumatoid arthritis: results of phase I dose escalation study. J Rheumatol. 23(8):1353-62. PMID: 8856613

Jaworski TM, Bradley LA, Heck LW, Roca A, Alarcón GS. 2005. Development of an observation method for assessing pain behaviors in children with juvenile rheumatoid arthritis. Arthritis Rheum. 38(8):1142-51. PMID: 7639812

Moreland LW, Heck LW Jr, Koopman WJ, Saway PA, Adamson TC, Fronek Z, O'Connor RD, Morgan EE, Diveley JP, Chieffo NM, et al. 1995. V beta 17 T-cell receptor peptide vaccine. Results of a phase I dose-finding study in patients with rheumatoid arthritis. Ann N Y Acad Sci. 756:211-4.  PMID: 7645836



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