Research

 

Investigators in the UAB Division of Clinical Immunology and Rheumatology garnered research grants and contracts (excluding VA funding) amounting to ~$20.7 million in FY 2009.  For details on the research programs of our faculty, please visit the individual webpages under the "Faculty" tab.  Selected highlights of our campus-wide, multidisciplinary, or multicenter research programs can be accessed by clicking on the respective links below.

The Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC) (S. Louis Bridges, Jr, MD, PhD, Director) is dedicated to generating new knowledge and to applying such to the diagnosis and treatment of patients with arthritis, musculoskeletal and autoimmune diseases. This charge includes integrating and promoting fundamental research with clinical care, developing and applying new diagnostics and therapeutics, educating the public about arthritis, musculoskeletal, and autoimmune diseases, and training future investigators and health care professionals.

The multi-disciplinary Program in Immunology (Harry Schroeder, Jr., MD, PhD, Director and David Chaplin, MD, PhD, Co-director) consists of over 100 UAB Faculty who identify themselves as basic or clinical immunologists and are members of multiple units at UAB. A desire for excellence on the part of the UAB faculty, coupled with the relative youth of the institution, has promoted a collective attitude of interdepartmental cooperation and collegiality.

The NIAMS MCRC (Multidisciplinary Clinical Research Center). Directed by S. Louis Bridges, Jr, MD, PhD, Division of Clinical Immunology & Rheumatology is a program designed to foster and promote research related to the causes, diagnosis, treatment, and improved care of patients suffering from arthritis and musculoskeletal diseases (MSD). To this end, highly-rigorous fundamental and clinical research is supported with state-of-the-art methodology with the following mission: (1) To conduct outstanding, innovative research projects drawing on the unique strengths of the AMC and using state-of-the-art tools from statistics, epidemiology, outcomes, health services, and behavioral research; (2) To foster the development of new projects and the development and application of new evaluative, analytic, and translational methods to research in arthritis and MSD; (3) To promote the training of new, and the continuing education of established, clinical investigators in the most current methods of research and evaluation applicable to arthritis and MSD

To complement ongoing research, the RDCC (Rheumatic Diseases Core Center), (NIH/NIAMS 5P30 AR048311) directed by John Mountz, MD, PhD, has a strong obligation to provide access to innovative experimental methodologies. As such, the RDCC supports three scientific cores: (1) Comprehensive Flow Cytometry Core (CFCC) directed by John D. Mountz, MD, PhD; (2) Analytic Imaging and Immunoreagent Core (AIIC) directed by Kent T. Keyser, PhD; and (3) Analytical Genomics and Transgenics Core (AGTC) Facility directed by Robert A. Kesterson, PhD.

CERTs_LogoCERTS (Center for Education & Research on Therapeutics of Musculoskeletal Disorders). The mission of the UAB CERTS is to evaluate the effectiveness, safety and impact on health related quality of life and to educate practitioners, insurers, policy makers, and the general public about Musculoskeletal Disease (MSD) therapeutics. The director of CERTS is Kenneth Saag, MD, MSc, Professor of Medicine in the Division of Clinical Immunology & Rheumatology.

coere_LogoCOERE (Center for Outcomes and Effectiveness Research and Education). The mission of the UAB COERE is to build and maintain a successful program of research targeted at improving the quality and outcomes of health care. COERE is directed by Kenneth Saag, MD, MSc, Professor of Medicine in the Division of Clinical Immunology & Rheumatology.

UAB Center of Research Translation (CORT) (Kenneth G. Saag, MD, MSc, Director; S. Louis Bridges, Jr, MD, PhD, Co-Director; P50AR060772). Gout affects roughly 1-2% of the U.S. population. With the “Graying of America”, the societal burden of gout will likely grow.It is well known is that gout, hyperuricemia, and vascular disease are more common among African Americans than Caucasians, yet little is known about the impact environmental factors have in increasing risk of gout in this minority population. To address these gaps our multi-disciplinary UAB CORT is conducting 3 research projects focused around the theme of "Gout and Hyperuricemia: from Bench to Bedside to Backyard”.

Click here for information about participating in CORT research studies.

ACIP_LogoACIP (Arthritis Clinical Intervention Program). ACIP is a full service clinical trial unit that conducts studies in rheumatology (Phase I-IV). Current studies focus on rheumatoid arthritis (RA), gout, scleroderma, lupus and vasculitis. Jeffrey Curtis, MD, MS, MPH,  is the Medical Director of this program.

 

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