Welcome to Targeted Metabolomics and Proteomics Laboratory
One-Day Workshop on the Analysis of Metabolomics DataTuesday, December 17th, 2013
There is a substantial emerging interest in the use of metabolomics to understand molecular basis of disease. Nuclear magnetic resonance (NMR) and more recently liquid chromatography-mass spectrometry analysis (LC-MS) have been used to determine the metabolites associated with disease. LC-MS has reproducibly revealed the presence of thousands of ions, representing compounds many of which have not been previously characterized.
Go to One-Day Workshop web page.
2nd Annual Workshop on MetabolomicsJune 16-19, 2014
The 2nd Annual Workshop on Metabolomics will be held 16-19 June 2014 on the campus of the University of Alabama at Birmingham.
The course is jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Department of Pharmacology and Toxicology at UAB.
|Figure from J Chromatogr B Analyt
Technol Biomed Life Sci.
The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators. The laboratory has four mass spectrometers, two triple quadrupole instruments (AB Sciex 3200 and 4000), a quadrupole-linear ion trap instrument (AB Sciex 4000Qtrap), and quadrupole-TOF (AB Sciex 5600 TripleTOF). The AB Sciex 5600 TripleTOF is particularly powerful for comprehensive and targeted proteomics, lipidomics and metabolomics. The recent addition of an Eksigent microflow 200 LC provides significant improvement in sensitivity for the triple quadrupole instruments.
Two fourier transform-ion cyclotron resonance instruments - supported by NCRR grants - are in the Biomedical FT-ICR Mass Spectrometry Laboratory (http://www.uab.edu/BiomedFTICR/). Contact Dr. Matt Renfrow about use of these instruments (email@example.com; 205 996-4681).