Annual Workshop on Metabolomics

The 6th Annual Workshop on Metabolomics will be held July 22-27, 2018 on the campus of the University of Alabama at Birmingham.

The course has been jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Departments of Chemistry and Pharmacology and Toxicology at UAB.

Details on the workshop can be found on the Metabolomics Workshop web page.

Recent publications from TMPL

Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics.
Hough KP, Wilson LS, Trevor JL, Strenkowski JG, Maina N, Kim YI, Spell ML, Wang Y, Chanda D, Dager JR, Sharma NS, Curtiss M, Antony VB, Dransfield MT, Chaplin DD, Steele C, Barnes S, Duncan SR, Prasain JK, Thannickal VJ, Deshane JS.
Sci Rep. 2018 Jul 9;8(1):10340. [doi: 10.1038/s41598-018-28655-9] [PMID: 29985427]

Methods for assessing mitochondrial quality control mechanisms and cellular consequences in cell culture.
Redmann M, Benavides GA, Wani WY, Berryhill TF, Ouyang X, Johnson MS, Ravi S, Mitra K, Barnes S, Darley-Usmar VM, Zhang J.
Redox Biol. 2018 Jul;17:59-69. doi: 10.1016/j.redox.2018.04.005. Epub 2018 Apr 10. [PMID: 29677567]

Genetic deletion of 12/15 lipoxygenase promotes effective resolution of inflammation following myocardial infarction.
Kain V, Ingle KA, Kabarowski J, Barnes S, Limdi NA, Prabhu SD, Halade GV.
J Mol Cell Cardiol. 2018 May;118:70-80. [doi: 10.1016/j.yjmcc.2018.03.004] Epub 2018 Mar 8.

More Publications

About TMPL

The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators. The laboratory has three mass spectrometers, a triple quadrupole instrument (SCIEX 4000), a quadrupole-linear ion trap instrument (SCIEX 6500 Qtrap), and quadrupole-TOF (SCIEX 5600 TripleTOF). The SCIEX 5600 TripleTOF is particularly powerful for comprehensive and targeted proteomics, lipidomics and metabolomics. The combination of Eksigent microflow 200 LC and 415 nanoLC with the mass spectrometers provides the highest possible sensitivity for sample analysis. The SCIEX 6500 Qtrap is fitted with a SelexION™ interface for ion mobility studies.

Contact Dr. Matt Renfrow about use of hi-resolution Orbitrap Velos instrument (renfrow@uab.edu; 205 996-4681).

A Bruker MALDI TOF-TOF instrument is available in the Comprehensive Cancer Center Core Laboratory of Dr. Jim Mobley (mobleyja@uab.edu; 205 996-6363).

New sample and data-handling arrangements in TMPL – investigators please note



MRM
Figure from J Chromatogr B Analyt
Technol Biomed Life Sci.
[PMID: 20346741]
MRMPath
MRMPath