Director: Steven M. Rowe, M.D.
The CF Clinical & Translational Assay Core examines efficacy and toxicity of emerging CF therapeutics in human cells and tissues using human primary nasal airway epithelial cells and bronchial airway epithelial cells (from bronchoscopy or other surgical remnant tissues). The Core also provides expertise in the nasal potential difference measurement, an important endpoint in cystic fibrosis clinical trials, and a means to understand pathogenesis of cystic fibrosis and other metabolic diseases. These clinical assays help bridge the gap between preclinical animal studies and clinical trials and contribute to therapeutic development in the CF Research Center.
If you have any questions please contact us at: GFJCFRC@uab.edu
Core capabilities include: