• Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression Core
    Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression Core

    Director: Eric J. Sorscher
    Email: sorscher@uab.edu
    Phone: 934-9640

    Director: Jeong S. Hong, PhD
    Email:  jhong@uab.edu
    Phone:  975-8929
    Website:  http://www.uab.edu/cfcenter

    The CFTR Expression Core facility assists researchers with the complex technology necessary to efficiently express the CFTR in experimental systems.  The Core maintains a repository of reagents for studying CFTR, including over 50 constructs containing mutations that lead to disease and CFTR plasmid molecules used as part of gene therapy protocols in CF patients in the past.  The core also assists with expression technologies using adenovirus and other technologies.

    If you have any questions please contact us at:  GFJCFRC@uab.edu

    Core Capabilities include:

    • Clone and express new CFTR constructs using:
    • Plasmids
    • Adenovirus
    • Vaccinia
    • Characterize CFTR by:
    • Immunoblotting
    • Immunophosphorylation
    • Plasmid reagents