Factor D-deficient mice were developed to assess the contribution of the alternative pathway in complement activation. They exhibit no obvious developmental abnormalities and have been widely used to test various disease models. These mice have been described in:

Xu Y, Ma M, Ippolito GC, Schroeder Jr HW, Carroll MC, Volanakis JE. Complement activation in factor D-deficient mice. PNAS 98(25), 14577-14582. 2001

UAB Reference: U2007-0017

For more information or to request a license, please contact:

Eve Vick, PhD
Licensing Manager
Email: eve@uab.edu 
Phone: (205) 996-4740

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