Director:
Established: 1998
Mission
and Demographics
Chemoprevention relates to the intervention with chemical
agents that either abolish or delay the development of those processes that
lead to cancer. The difference in how
drugs are used to cure cancer versus how drugs are used to prevent cancer is
the basis for the Chemoprevention Center.
Chemoprevention involves the administration of one
or more compounds to prevent cancer and is a national research effort focused
on three goals: 1) identifying or
synthesizing chemicals to prevent the formation of carcinogens from precursor
substances, 2) halting the interaction of an active carcinogen with target
tissues, and 3) blocking the progression of precancerous cells to
malignancy. The Center currently
has three appointed faculty representing two schools and three departments at
UAB.
Center
Research
The Center’s basic research assists investigators in the
conduct of preclinical studies focused on the role of chemopreventive agents as
modulators of the carcinogenic process. Clinical trials have been conducted
at UAB to test the use of chemopreventive agents to prevent many cancers
including prostate cancer, breast cancer, dysplastic oral leukoplakia, cervical
dysplasia, and skin cancers. UAB was the first university to establish a center dedicated
to chemoprevention research.
Training
The Center assists graduate students from multiple
departments in their basic studies related to cancer prevention.
For additional
information:
Director: Clinton Grubbs, PhD
Email: Clinton.Grubbs@ccc.uab.edu
Phone: 205-934-6384
Administrator: MaryJo Cagle
Email: MaryJo.Cagle@ccc.uab.edu
Phone: 205-934-2081
Approved
by: Clinton Grubbs, PhD, Director
Date: April 3, 2008
Click here to return to the SOM
Research Web Site's home page.